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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PGR (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5241
Official gene symbolPGR
Full nameprogesterone receptor
Aliases,NR3C3,PR,
Gene summaryThis gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q22-q23
Gene position101000544 - 100900355  Map Viewer
Gene orientationminus
Gene size100190 bp
Gene sequence
OMIM ID607311