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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PEPD (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5184
Official gene symbolPEPD
Full namepeptidase D
Aliases,MGC10905,PROLIDASE,
Gene summaryThis gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.
LocationChromosome: 19   Locus: 19q12-q13.2
Gene position34012799 - 33877855  Map Viewer
Gene orientationminus
Gene size134945 bp
Gene sequence
OMIM ID613230