| Entrez gene ID | | 50940 |
| Official gene symbol | | PDE11A |
| Full name | | phosphodiesterase 11A |
| Aliases | | ,FLJ23693,MGC133355,MGC133356,PPNAD2, |
| Gene summary | | The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| Location | | Chromosome: 2 Locus: 2q31.2 |
| Gene position | | 178973066 - 178487977 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 485090 bp |
| Gene sequence |
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| OMIM ID | | 604961 |
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