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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDE11A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID50940
Official gene symbolPDE11A
Full namephosphodiesterase 11A
Aliases,FLJ23693,MGC133355,MGC133356,PPNAD2,
Gene summaryThe 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q31.2
Gene position178973066 - 178487977  Map Viewer
Gene orientationminus
Gene size485090 bp
Gene sequence
OMIM ID604961