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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PAX2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5076
Official gene symbolPAX2
Full namepaired box 2
Aliases,-,
Gene summaryPAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q24
Gene position102505468 - 102589698  Map Viewer
Gene orientationplus
Gene size84231 bp
Gene sequence