| Entrez gene ID | | 5046 |
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| Official gene symbol | | PCSK6 |
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| Full name | | proprotein convertase subtilisin/kexin type 6 |
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| Aliases | | ,PACE4,SPC4, |
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| Gene summary | | The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] |
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| Location | | Chromosome: 15 Locus: 15q26.3 |
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| Gene position | | 102030187 - 101844133 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 186055 bp |
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| Gene sequence |
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| OMIM ID | | 167405 |
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