| Entrez gene ID | | 5027 |
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| Official gene symbol | | P2RX7 |
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| Full name | | purinergic receptor P2X, ligand-gated ion channel, 7 |
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| Aliases | | ,MGC20089,P2X7, |
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| Gene summary | | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq] |
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| Location | | Chromosome: 12 Locus: 12q24 |
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| Gene position | | 121570622 - 121624354 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 53733 bp |
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| Gene sequence |
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| OMIM ID | | 602566 |
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