| Entrez gene ID | | 4893 |
| Official gene symbol | | NRAS |
| Full name | | neuroblastoma RAS viral (v-ras) oncogene homolog |
| Aliases | | ,ALPS4,N-ras,NRAS1,NS6, |
| Gene summary | | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). [provided by RefSeq] |
| Location | | Chromosome: 1 Locus: 1p13.2 |
| Gene position | | 115259515 - 115247078 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 12438 bp |
| Gene sequence |
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| OMIM ID | | 164790 |
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