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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NME1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4830 Official gene symbol NME1 Full name non-metastatic cells 1, protein (NM23A) expressed in Aliases ,AWD,GAAD,NB,NBS,NDPK-A,NDPKA,NM23,NM23-H1, Gene summary This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq] Location Chromosome: 17   Locus: 17q21.3 Gene position 49230920 - 49239450  Map Viewer Gene orientation plus Gene size 8531 bp Gene sequence >NME1:14505072..14513602:Length=8531 GCAGAAGCGTTCCGTGCGTGCAAGTGCTGCGAACCACGTGGGTCCCGGGCGCGTTTCGGG TGCTGGCGGCTGCAGCCGGAGTTCAAACCTAAGCAGCTGGAAGGGTAAGAGGTGTTCGGG ATCCTGAGAGGAAAAAGAAAGGAGTGTAGTCGCGGGAGTGGGTTAGGTGAGGAGTTAGTG AAGAGATGAGTTCAGCTCTAAGAGGCGGCGAGGAGGATCGGATGGGAGGAGGGGCAGGGA GCGCCTGTGGACAAGTGCAGACCGGTCGGCGCACGTCCCACGCCACGTGGACTCGCCTTT GTCGGTGGCCGCCTTTCTCGTCAGGCCGCGACGACAGGGCTGTGCCTTATTTGTGTCTGT CGAGAGCAGTGCCGGGCACGGAGTTGGCGCTCTGTAAGTGCTTGCTGAATAAATGACGGG TGTGTGTGTCATTCATTCAGCAAGCACTGAGTGCTTACTGTTGTGTCACCGGGACCGATG TGGAGGGACATTTTTAGGGTGTATTTCTGGCGCTTTAGTCCTGTTTTCTCCTGGACAATT TATGCTTGCCCCGCACCCCATCGTGCGATTCTCCGCAGTCTTTGGGCTTTGTCTCTCTCT CTTTTTTTTTTTTTGGAAGTTGCAGAATGGTGATAAATGATTTTCTTTGCTCCTATTGAC TGCTAGGCCCTGTGGCTAGGTACCATAGAGTCTCTACACAGGACTAAGTCAGCCTGGTGT GCAGGGGAGGCAGACACACAAACAGAAAATTGGACTACAGTGCTAAGATGCTGTAAGAAG AGGTTAACTAAAGGACAGGAAGATGGGGCCAAGAGATGGTGCTACTGTCTACTTTAGGGA TCGTCTTTCAAGGCGAGGGGCCTCCTATCTCAAGCTGTGATACAGGGTAGGTCATGAGCG CAGTCTTCTGTAAAATGAGGGATCTGGACGGAATAGTTACTCTCTAGGCTTCCTTTCAGT ATGATGTCCCGTATCAGATATTCCTAATGTCTGTAGTTCTCCCACACCCCACCGTTTATT GGCTAGTCAAAATATTCTTTGCATTGTAAAGTGTAGCATAACATTACAAGAATGGATTAA TGGGTTGGGAATGCTGGGTTTTGGCCTTCATTCTGGTGCTGTGGTCCTGTTTCCTCATTT GTAAAATGAAGGGGGTTGTAAAGATATATTCTCTAAAACCCCTAATGCTATGGCTGTGGC ATTAAGTCAAACTATTATTTCTTACTGCTTTGTACCGGACATCACTTTCACATTAGTAAA ACTTTTCATCAGTGTAGTTTCTCCCAAGCTTGATTATTGAGAAAGATAGTGCCTTGTTTT TAACATCCTGTATCCTAGTTCCACCGCAGTGTTTGGTACACAGTAGATGTTTAAAAGAAG CTTATTAAATCAAATGGTGGCCAGGCTCATGGGGCTCACGCCTTTAATCCCAGCACTTTG GGAGGCTGAGGTGGGCAGATTACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACATG GTGAAACCCCATCTCTAGTAAAAAAAAATACAGAAATTAGCTGGGTGTGGTGGCACGCAC CTGTAGTCCCAGCTATTTAGGAGGTTGAGGTAGGAGAATTGCTTGCCTGGGAAGTGGAGG TTGCAGTGAGCCAAGGTCGCACCACTGCACTCCATCCTGGGCGAAAGAGCAAGACTCCAT ACCAAAAAAAAAAAAAAAAATCAAATGGGGCTGGGTGTGGTGGCTCATGGCCATAATCCC AGCACTTTGGTAGGCTGAGGTGGGCAGATCACTTGAGGACAAGAGTTCGAGACCAGCGTG GGCAACATAGCGAAACCCCATCTCTAAAAAAACCCCACAAAAACCAAAACAAATGAAAAT AAAATAAATCAAATGGGATAGAAATTATAGTCCTTGCTTTTGGATCCTTTCCCACATTGA CATATTAGTTCATAGATCAGGGGACTGGGGAGGAATTGGGTTTTTACCAGAGGGAGACCT GGAGCTGACCTGACAGATTTAAACCAGCTTTATGGGATAATCCGCTTGAGACGGATGACG CTGTAGGCAAGTGATTCACTGCTGTTTCATTCCTCTACCTGCCTATCCCCAGAACCATGG CCAACTGTGAGCGTACCTTCATTGCGATCAAACCAGATGGGGTCCAGCGGGGTCTTGTGG GAGAGATTATCAAGCGTTTTGAGCAGAAAGGATTCCGCCTTGTTGGTCTGAAATTCATGC AAGTAAGTGGACTTCATTGTTCCCATTTTGATTCCTTCATAGTATAGGAGAACACTGTGA TTAACCTGTTTCTCCCCGTCTTTCTTATTTAAAGTTCTCCACGGTAGAGTGAACACAAGT GTCTTGAGACCTGGAAACTCCTCAGTGCCCTAGCGTTTGGCTACATCTTGGAACAAACCA AGTTATTTAGGATTTTCCAAAATAGTCTCTGTAATAGGAGGTGCATTGCTACGGGAAAAG CAGTGCAGAGTTCCACATATGACTGCATCTCTGTAATTTCTGACTGAGAGCTGAGCATGT TTGAGTTCTTGGTCTTGAGCTTCCTGAGCAGATAATTTTAGAGAGATTTTTTTCCCCCTT TGAGACAGGTTGTTTTTTAGCAAGAAAGTCTTTCCATCATCAATTACTAGACACTAATAA ATGCTTATTGTTTAGCATATATTAGGTATCATAGGAGCTGGTGGAGGAAAACTATGGTTT TGGTTTTGGGGAGGTTCTTCAGAAACAGCAGAGAGCAGATGTACCTGCAAGCTACTTACA AAGCAATCTTTTGATAAATGCAAAGGATTGATTGACCAATAACCCTTCTTCAAACAAATT CTAGAGATAATCCAAATTCTCGGCTGGGTGAGGCATAGTGGCTCATACCTGTAATCCCAG CACTTTGGGAAGCCAAGGCAGGCTGGTCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGC CAACATTGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCATCAGGGTGGG TGCCTGTAATCCCAGCTATTCGGCAGGCTGAGACATAAGAATTGCTTGAACCAGCCAGGT GCGGTGGCTCATACCTGTAATCCTAGCATTTTGGGAGGCTGAGGCGGGCGGATCACCTGA GGTCAGGAGTTCGAGACAGCCTGACCAATATGATGAAACCCCGTCTCTACTAAAAATACA AAAATTAGCCAGGCGTGGTGGCATGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGACA GGAGAATCGCTTGAACTGGGGAGGTGGAGGTTGCAGTGACCGAGATCGCATCATTGCACT CCAGCCTGTGCAACAAGAGCAAAACTCCATCTCCAAAAAAAAAAAAAAAAAAGAATTGCT TTTGAACCCAGGAGGCGGAGGTTTCAGTGAGCCGATATTGCACCACACTGCAGCCTGGGC AACAGAGGGAGGGAGACTCTGTCTCAAAAAAAAAAAAAGAATTCCAATTCTCAAATCAAA TAGGGGATAGTATGTTTTCTAAAAGGGAATCAATTTTGGACCCTTCTAGTGCATTTTAAA ATTTAGTTTGACTTGCAATTTACTTCCTATGTGATATTTTAGAAAAACTGCTTTAGGGCT GGCACAGTGACTCGCCTGTCATCCCAGCACTTTGGGAGGCTCCGTCTCCAAAAAAAAAGA AAAAAAAGAAAAGAAAAACTGCTTTAATGTAAAAGAGGGTAGACTGATGTTCATGCTGAG AGGAGAATATGGTGTCCAAGGTCAAGGAGCTGGCATCTAATGAAGGTTTTCTTGCTGTAT CATCCCATGACAGAATGGAATAGCAAGAGAGTGCAAGAGTGAGAGAGAGCAAGAGGGGGC TGATGTTGATTTTATAACAAACCCACTCCTGAGATAAGACATTAATCTGTTCATGAGGGT GAAGCCCTCATGACCTAAACACCTCCCATTAGGCCTCACCTCCCAACATTGTTGCATCGA GGATTAAATTTCCAACATACGAACTTTGGGGGACACATTCAGATCACAGCAGAAGGTAAC ATGAGATGGATGTGTTGTTGATCAGGCATTTACCATATGCTGGGCACATATGTTTTCTGA TTTAGTCTTCATGCCAGCCTTGAGAAGTACTTACTCCTGTTCTCGTGGTTGTTAGTGATG AGCAACCTAAGGCTTGGAGAGGTTCAGTGATGTGCCTGATAGCATACAGTGATGCCACTG GAATTTTAACTTGAGTCTCTCTGACCCCTGAGTGCAGATACTTTCTCCTTTACATTGAAT TTCCTATTAAGGATATATGGGTTTGGTGAAGAATGGACGGAAGGATAGCTGCCATGACTC TAAAGGGGCATTTAAATCTGGTGTGGAGGCAGGAAGCAAGGGAGAACTTGAGGTTCCCAA CCCCCAAGCCCTTAAAAAAAGCCCGTGATCTGTTTTGCAGACTAAAGATAATCAGTTAGG GCCTGGCGTGGTGGCTCACACCTGTAATCCCAGCATTTTGGGAGGTCAAGGTGGGTGGAT CATCTGAGGTCAGGAGATGGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTA AAAATACAAAATTTAGCTGGGTGTGATGGCGCATGCCTGTAGTCCCAGCTACCAGGGAGG CTGAGGCGAGAGGATGGCTTGAACTCGGGAGGTGGAGGTTGCAGTGAGCGGAGATCGAGC CACTGCACTCCAGCCTGGGTAACAGAGCAAGACCCTGTCTCAAAAAAAGATAATTAGCCG GGTGTAGTGGTGCACACCTGTAGTCCTAGCTACTGAGAATCTGAGGCAAGAGGATTGCTT GAGCCTGGGAGTTTGAGGCCGCAGTGAGCTATGATCATGCCATTGCACTCCAGCCTGGGT GACAGAAAGACCCTGTCTCAAAACAAACAACAAAACCAACAAAAAGATAATTGGAACCAA TTAATAGAATTAAAAAAGTATTCTGATAAGGGAAGGTCACCTCAGGGTCTGTTAGACTTC CACAACAAAAGTCTTCCATTTGGATAGGAAAGGACAGGGCGAGGGTTGGATCCCTACCAC GGAGTGATTATATGGCCATGTAATTTTACTTTGGCAAGTGATGATAACTGGTGGCTGAAT GATGGGGCTTCTGGGCAGCCAGTCTCCACATCTGTGTGTGTCTCTGATGTGTGTGATATG CGTCATACAGTGCAGTACCACAGAGCTGGAAAAACCATGGGACCCTGTTAGATTTTAACA AGCGTATATGCAGTACAAGAGAGAACACAGCCAAACTGAGTTGAAACTGCTAAGCAGATG GTTTGTTCTCTAGCTAACTTGATTCGTTCCCACATATTAGCCTTGCAGTATGAGAGGTTC TAATTCATTTTTCAGCAAAATTATTTATTACTAGATGTCATGCACTTTTGGGTGATTTGC AGATACCTTTGGTAATCACATGGTCATCACTGCTGGGCTTTTATCCTCTGAATAAACGTG AAGCATCCCTGGGTAATGGCCTGGTTTAGTTTGCTGCTCATTAAATGCCAAGACTTGCTT CCTGGTGTCCTTCTAACATTTTATTTGGGGTTTGCTCTGGGAATGGAAATTTATTGTATT GTTGATTTTCCTGTCTAAAATGAGATAGTTGAGGGCCAGGCATGGTGGGTCACGCCTGTA AGCCCAGCACTTTGGGAGGCGGAGGCTGGAGGATCACTTGAGTCCAGGAGTTTGAGACCA GCCTGGGCAACATAGTGAGACCCTATCTCTACAAATAATTTTTTAAAATTAGCCAGGTAT GGCTGGGCGCGGTGGCTTACGCCCGTAGTCCCGGCCCTTTGGGAGGCCAAGGCAGGCAGA TCACCTGCGGTCACCTGAGACCAGCCTGGCCAACATGGCGAAACCCTGTTTCTACTAAAA ATACAAAAATTGGCCAGGCATGATGGCCGCCACCTGTAATCCCAGCTACTTGGGAGGCTG AGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGGTTGCAGTAAGTCAGGATCACGCCAC TGCACTCCAGCCTGGGTGACAGAGGGAGACTCTGTCTCAAAATAAATAAATAAATAAATA AAATTAGCCAAGTCTGGTAGTGTGTGTCTACAGTCCTACCTACTCGGGAGTCTGAGGCAG GAGGATCACTTGAGCCCAGGAGTTTGATTTTTTTTTAAATGAGATAGCTGGATTTAATTT TAATGTTCTGTGGTTTTATTATCAGTCAGTGCCAATAGGGAGACAACTGATATAAAATTG GAGAAGTACATTTAGTCCTGTCACTGCTCCCTTCCAGTGTGGAGAATGAATTGGGTTATA ACAGAATCAGTGAGCCCAACCGCTCATGTTTTACATAGCAGGGTGGATGAGGGGAAATTA AATGGATTATATGTCCTTAGATGGTTTGGGGGTTATTCTCATTCTCTGTCCTGTTGAATA GGCTTCCGAAGATCTTCTCAAGGAACACTACGTTGACCTGAAGGACCGTCCATTCTTTGC CGGCCTGGTGAAATACATGCACTCAGGGCCGGTAGTTGCCATGGTGAGTGTGCCTGTGTG GGATACTCCAAGTATGCATTGCTTGTCATCTGTGCTAGGCTCTCTTCTAGACACTGGGGA TACAGCCATGAATGAGACCAAATAGATACCTGTTTTCATATACCAGCTAATGGTTAGTGA TAGGCTTCAGAAATGAAATATGCCCAGAAATGAATAGGAGTAGCAAATGATCACTTTAGA TTGGGTGATCAAAGAACGCAATTTTTAAGCTGTGATCTGAATGACAAGAAGCAGCGATCT GAATGACAAGAAGCAGCCAGCCATGTACAGAATCACAGTGAAAAACATTTCCAGCCAAGC AAACAGCATGTGCAAAGGTCCCAGGGTGGGAATGAGCTTGGCTTTTTGAAGTACGGGAGG AGAGTTGAAATGCCCGAAGCCTGATGGGTGGGAGGGAAGTTGGGAGGTGAAGAGTTCAGA GGCATGGGCAGGGGCCTTCTCTCTTAGGGGTGTGTTGACCATATACTTCCTGAGTGCTGG GAAGCTATGGGACACTTCACACTTGGCATTTCTTTTTTTTTTTTTTTTTGAGACGGAGTC TTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCCATCTCGTCTCACCGCAAGCTCCACC TCCCGGGTTCACGCCATTCTCCTGCCTTAGCCTCCTGAGTAGCTGGGACTACAGGCGCCC GCCACCACGCCCAGCTAATCTTTTCGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAG CCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACTCCCCTCAGCCTCCCAAAGGGCTG GGATTACAGGCGTGAGCCACTGCGCCCTGCCCACACTTGGCATTTTAAGGAGGCTGCTCT GGTTGCTGTATGGAGAATACATTGTAGAAAGGCAAGCATGAGGGCAGGGAGATCAGGATC CTCAGTGCTGGAATAAGTGGATATACTCTATAAACATTTGTTCAGTGAATGAATATAATC TTAAGGGGCCTTTTTATTTTTCCTTTTTTGAATTAATAGTTGCCAGATTTTCTGCTGTGA TTGGTTTTCTTCTTTGACCATATCTTCTTCTGTCCTTGGAGGTCTGGGAGGGGCTGAATG TGGTGAAGACGGGCCGAGTCATGCTCGGGGAGACCAACCCTGCAGACTCCAAGCCTGGGA CCATCCGTGGAGACTTCTGCATACAAGTTGGCAGGTGAGATTTTGGTATTTTTCCCCCTT TTCCAAAATCTGATTTAGTTGCCACAAGGATTTGGGTTTCCGAGGCTGGAGGTAGACATG ATACCATATGCAGGTTGATTTTATCGGAGTTTATTGTTTTCCTCCCTCTTAAGTTGGCGT TTGGCTTTGGTTGTTAACATCACTTAGTCGTACCTCTGTTACACGAAGTGTAGAACCTGG TACAACACACTTTGCTGGCCAGTCTTTCCTGAAGGCTCTCACTGTTTGCACCAGCGTGGC CGGGAGGGCTGGATGTGGGGAGGGCATTTTTCAGCCTTAAGTGAATGGCCATTGTAGGCT TTTTCTTTTAACATGGTCTAATGTCCATGGAGCTTCAGCTTTTATGCTGCTGTGGCTGTA GATTTCTGGCAATGGGCGCATTTTAATCCTTCTGGTCTTGGTCATGTGACTATCTCTTTC TCCACCCAGGAACATTATACATGGCAGTGATTCTGTGGAGAGTGCAGAGAAGGAGATCGG CTTGTGGTTTCACCCTGAGGAACTGGTAGATTACACGAGCTGTGCTCAGAACTGGATCTA TGAATGACAGGAGGGCAGACCACATTGCTTTTCACATCCATTTCCCCTCCTTCCCATGGG CAGAGGACCAGGCTGTAGGAAATCTAGTTATTTACAGGAACTTCATCATAATTTGGAGGG AAGCTCTTGGAGCTGTGAGTTCTCCCTGTACAGTGTTACCATCCCCGACCATCTGATTAA AATGCTTCCTCCCAGCATAGGATTCATTGAGTTGGTTACTTCATATTGTTGCATTGCTTT TTTTTCCTTCT OMIM ID 156490