| Entrez gene ID | | 4437 |
| Official gene symbol | | MSH3 |
| Full name | | mutS homolog 3 (E. coli) |
| Aliases | | ,DUP,MGC163306,MGC163308,MRP1, |
| Gene summary | | The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq] |
| Location | | Chromosome: 5 Locus: 5q11-q12 |
| Gene position | | 79950294 - 80172634 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 222341 bp |
| Gene sequence |
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| OMIM ID | | 600887 |