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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP15 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4324 Official gene symbol MMP15 Full name matrix metallopeptidase 15 (membrane-inserted) Aliases ,MT2-MMP,MTMMP2,SMCP-2, Gene summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq] Location Chromosome: 16   Locus: 16q13-q21 Gene position 58059282 - 58080805  Map Viewer Gene orientation plus Gene size 21524 bp Gene sequence >MMP15:11673481..11695004:Length=21524 ACGACTCTTTGATCCCTCCCCTAAGACCTCCTTCCCGTCCGCCTAGGCCTCGGTATCCCC CACCAGGTATGAGAAGGAGGAGTCTTCATTCTTCCCAGGCGGGGAGACCACGCCTTCCCT GCCTCCTCCCTCCGCGGGGGGTCGCGTTGGAGGTCACCCCCGCCCCCTAGGCGCTGGGTT GGGAGTGACGCGGGGTGGGCTGGAGAGGTTTCCTGCCGTCTGGGAAGCGTAAACGGACCG CCCACCTGTCGGGCCTCGGCCGCCCGCACCTGCTTGTGAGAAGCCTGCGGCTGGGGCACC GCCCCCGGTCCCCGCCCGGGTCCGCGCATTGGGAGCACACTGGCCCTTTAAGAGCGCGGC GGCCGCGGCGCGCGGGGAGGAGGGCTGGGAGCGCCCGGAGCCGCGCTGAACTCGCCGGGG ACGTCGGGCGCCCGCTCCTTGGCTGGCTCGCTTGCTCTCTCGCTCGCTCTCTCGGGTCGG CTCCCTGCGCCTCCTCCCGGGACTGCTTGGGGACCCGGGCCCGGTCGGGCGCGGCGGCGA GCAGAATCCCCGTGCAGGAGGCGCGCGCTCCGGGCAGCGCCCGGCCCCGGGCATGGACAG AGGGAGCTGGGCGCGCAGGGAGCGCCGCGGGACCGGGCGGCCGGAGCGCTGAGCCAGACA AAGGCTCCGGAGTTGCGCTTGCTCTCGGGAGCCGGGCCCCAGGCGCTGGGCGCCGAGGCT GCGGAACCTCGCCGGGGGCAGCTCCGGTCGGCCCCCTTTCCCGCCGGCTGGTTCCGAGCT CCCGGACCTGCCCTGCCCGCTTCTCCTCGGGCTTGGGAATTTGCCGAGGCGACCTAGGCG GCTCCGGCGGGGACCGGGAGCCCGAGGTCCGCGGCGCGCCTGCCGGGCCAGGAGCCAGGG AGCGTCGCAAGTTTCCAAGGCGCGTGCGAGGATCCGGCGTGCAGTGTTCCGAGCTGGGCT GGGCGCCGAGAGCATGGGCAGCGACCCGAGCGCGCCCGGACGGCCGGGCTGGACGGGCAG CCTCCTCGGCGACCGGGAGGAGGCGGCGCGGCCGCGACTGCTGCCGCTGCTCCTGGTGCT TCTGGGCTGCCTGGGCCTTGGCGTAGCGGCCGAAGACGCGGAGGTCCATGCCGAGGTAAG ACCCCCGCCCTGCCCTTTGGCTGCGGGCTGGGGGCTTGGAGGGAGAGGCGCCACGTCCGC AGGCTGGGACTTGGAGGTGGAGGGAGCGGAGACGCGCCCCCTGTTCTGGGCCGTGGCGGG GAAGCAAGCGGACTTGGCAGTCTGCCCCTCCCCAGCTCGCCCTCTGCAGCGCACCTCTTC GCAAACCCTTGAGGGCGCAGGGCCTCGCTCTCCTCCCCGCTACTCCTACAGCCCTGTTCT GGGCACTGAGCCCCCACCCCGACCCCCTTACATTCAGCCTGTGTCCCGGGAGCCGCTTCC GCCGCCCCCAGCCCTTGCCTCCCCTCCTTCCTTCCCTCCAGGGCAGCCGATTCCTCGAGA GCCCGGCTGGCGCGCAGTGGCGCTCTTTGCGAGTGGGGAGGGGGCTGCTCTCGGGGACAG CCACAGGCGGAGCAAGAGCTGGGCGGCTGGGCAACTGCGCTCCTGCCCAGGTGGCCTCCC GTCTGGGTGATACCGAGCCGCGCACGGCGGGCCAGGATGGAGGCGGGGGGATGGGTGCAA ACGGCTGAGGCAGCGGACTCGGGTTGCGGGGGCGCTTTGGCGACTTTCTGCGCTTTTGCG AGGAAGCCTAGGCACGCCCGGGCGGGGTCCTAAGGACGGACCCTGCCTCCCACAGCGCTT CCTCCCAACAGCGCCCCTACGTCGAAGCCCTGGATTCGAGAGGGTGGACCCCGCGCCTCT CTTCGCTAGGAGCCCGCTTGGCGTCCCTCCCGGGGCCCCGCTCTGGATGGGTCCCGCGGG TGACCAGGCGCGACATCCCGGCGTAGAGCCGAGTCCAGCCAGCGCCCCAGCTCCATGGTG TCTCCCGAGCGAGGACACCGAAGGCGCCAGCTTTCTTGCCCCAGAGCAAGAGCAGGGTCC ACTCTTCCCCGACTTCTAAGACCTGCGCCCTGCCCCAGATAGGCGGGGAGAGGACTTGGG CGGGGAGTAGGGAGAAAGAACCACCCCGGAGCCGCTTCTGAACGGTGCTCAGGCCTTGGT GCCCTTGGGCTGCCCGGGCTGCGGGCCTGAGCGCCGTTTCTATTTGCAGCTCAGCTGGTG CTCCCTCCCTGGCCCACGGCGGCTTTCCCACCTCTCCGGGCTGCCTGGGAGATTTTTCCG ATGGAAGCTTGCCCTTCCCCGCCCTACTTTAATAAAAGCATAGAGGAAGGGCAGGGAATT CCTCCTGGGCTCGAGTTACACCTCCCAGCCATTTCCCCACCTGCTCTGCCCTCCCTCCCT GGCCTGGCCAGGGAGAGCTGAAGGAGGAGCCAGGCCCTGGTGGGAGGCAGGATAGGAGCC CCGCCCCGACCCAGTCTGGCCACCCTCCCCCACCCCATTCACACAGGCAGGAGGAGCTTT AGGGGGCTCCTGTTGGTGAGGATTACCCCTCAGCCTGTGACCCAAGTACTGGGCGGAGAG TGCCATTTGGGCCCACCTGCCACTCTGGGCTGGAGTGCCAAAGAATTTCAAGTCACAGTC CCACCATTGAGTTTCTAATCTACTTAGGGATGGCGTCAATACATAGGAAGCAGTGATGGA ATTCAATGGCCGTGCATTGCTAATGGCATCCTAGCTGGCCAGGAGCTCAGGGGTGCAGGG ACCTGTAGTTGGAGGGGCTTCACTCTCTCTCTCTTCTGCTTTTCCAGTTCCATCTCACCC CTACCCCAACTCCCCAGCTCAGGGAGTGCCCACAGCTCGATGCCGCCAGGGAAGAAGCCA TGGTTGCGTTATCACAAACCGTGCTCCTGATCTGGAGGTTGTGACTGTCCTGGAGCCCTA CTCCTGGGGAAACACTTGGGTTGGACCTGGGCAGTGACTGGAAGAGACCCCGGAAGGTTT AAGGAGCCTTGAATGTTGGCAGCCATGCAGATAGAGGGCTAGAGACAGGTGGAGTGTCCC AGCTCCTACAGTTGGCTTTGGGTACAGGCTGCTTCTAGGGTCCCATCAGGTCTGGCCACA TGTGGGCCCAAAGAGTCAAATGGCCTCAGCAGCCAGCCCATCTGCCGGGGGCTGTGGCCT CAGACTCCTGGGCCTGGCCTACACCCTGTGTTGAGCCTCCCTTCCTTGGAGAAGGCTGGC TCTCTCATCCTCACCCCAGCATCCACACAGCCTCAGGCCTCCAGTAGGGTCACAGCTGGG ACCTTCTCGGAGCAGCTTGGCAGCTGAGCCAAGGCCAGCCTCTCTCCACTTCCTCTCTCC CCTCCCAGGGTGGAAGCCACAGGACTTTCACGAGGCTGAGACATCAAGGAGCCTGGCATG TGCTAGGAACTGACAAACACCTGCAACCTGCCAGGCCCTAGCCCACCACTGAGCTGCCAC GTCCTATCCCACATTCTCCCTTGGATGTCCAATCCCAGTCTGTAGCCATTCCGGGCCAGA TCCCCACCTGGCTGAGGTGCTCACTGTTGTTCCTGCCCTGCAGGGCTGAGAGTCTCCAGG CTCACCGGGGGAGCTCTTATCTCACCTGCCTCCCCCTACCCCCTCCTCCCAGGCACAATT CAGGTCCTCAGCCTGCTCTGTGGAGGTGACTCAGGCTGCCAGAGTTCACAGGGGTGGTGC CACCACCACCAAAACCGATCCACCCGCCTTTCCTCAACAGGCCCACGAGTATCTTCCTAG CCCCTACCCAGCCACTGAGTAGATGAGGCAGCGGGGGTGGGGGCGTTGGGAGGGGGTCAG CGTGAATTACCATTTTGACCTTCAGGTGAGCCACAGTCTTGGGCTTCCTTAGCTTCAGTC TCTACTAGCACTTCCATGCTGGCTCCGGGGGGGCCCCACTGGTCCCCTCTTTCTTTTAAA CAGAGCAAAACTACAGATGCCATCTGTGCCCACCAGCTAAGAAAAGGGAGTTAATAGCGG GGCCTTGTCATTGGGAATCTGCAGAAGCTGAATCTTCTCCCCCTCCCCTCTTGTCTCTGC TTTTTACTCTGTTTTCTTGCTAGTAGTAAATCACTCCTCTCCATGCTCTGTCAAGACCCA GAGAGAACTGGTCTGATTGGCACAGCCAGGGACCTAGATCTCATTGGGCCATGCCCTTCA CACCCAGCCCTTGCCATGTTTCCGAGTTGGGGCTGCCCTTGGGTCCAGCCAGTCATCTGT CTCCTTGCAGAGAACAGCCCAGTGTAAGCTCCTTGTCTGAGCAGTGTATTGGCCTGACCT TCCCATTGTGACCTCTGAACATAAATACCTCCTTTGCCCCACCCCAAGGGATGTTGATAC TTAAAAGATATCCATGAATGTGGAGAGGAGCAACATGGAAATACACGCTATCCCCACCCC CAAAAGAAGACTTTCCCCAAAAGCCCAGTGCCCACTGCTATCTCTTATGCCCATTCAGGA TGGCTACACTGCAGGCGTGGAAAAGCCCCTCCCTGCCGAGCGGTTTGTTCTGCTGTCCCT CTGTGGCCCTTTTGTTGTTTGGTCCAGATGATCCCTTCCATCATCACCTCTGCCCTGCTG GGAGTTTGACCTCTGCCTCAGGCTAGCTGTGGTGGTCACTATGAGAACCACTACTTTCCA GATCAAATCAGAATGGGTATCCTCCATATCATCCCAAGGCTTAGGTGGCTCCCTGTCTTG GACACTCCAGCAGGAGCAATGCTTTGGTCCTGGAGATGTGTTTTCTGAGTCAGCAAAGAC AGAGAGGGGTTGTGGACTCTGCCCTTATCTTTCTCCTTTACAAAGCGGGTCCTGGGAGAA GCCCACCATTGAGTGTGAGGACCGGGACCCTGAAGGCGGCTGAATGCTCCAGACCTGAGA CACAGTAGGCACCATCTGGCTGGACAGCTCTGAGTGACGGCTCAGATAGGGCTGCTCCAC AGTCAGACACAGGTTCCAGGGATTCCTGAGACCAGAGGCCATGGAGCTGGGCCTGGATCC CAGAGGCAAAGAGGGATGCCTCTTCCCTAATCCCATGGCCCTCGTGGGAATGGAAGAAAA AGTGGGAAGAGACCCAACTCAGCCTCCAGTATCAGGACAGGTGGATAAGCCCCTGGTACC AGCCATTAGCCAGCCCCTGGAGATGCCCCCCATCCTGCTGCCATCGGCCGATGGTGATGC AGGCCAAGGTCTAGATCACCTCTCCAGGGCACTGGCACTGGCACTGCCTTGTCCTTCCCC TAGGAGTGACTGTCACCCTGTAGGGGTGAGAGTCCAGCTCCACGTTCAGCGTTTCTGAGC ATGGCACTTGATACATAGTGCACAACACGGTGGCCTACACCCTGTGTCCAGAGCCTCCCT GGCAAAATAGTGCAAAACAGTGACAGAAGCGAATGGCATTTACTGTTGGGCAAGTCACTG AATCTGTATGAACTTCAAGATCTCTATAAAAAGGGAATAGCAATGGTCTATCTGCTTGAT GGAGTTACGGGGAGATTCATTGCATTTATGTGCAAAACACTAAACGCTATGCACAATGCC TGGCACAGGGGGCCTAAGGAGGCGCAGGTGTTATTTTTGAGCACCTTCAACATACTTGTG TCTGTTGTGGACACAGACTAGGGATGTTTTGTAAGCGTTTTCACATTTAATCCTTGTATT AACTCTTCAAGTGTAGATGCTGTCATTACTCAATCTACAAAAGAGGAAACTAATACTGTG AGTTGAGAGAAATGACCCCCGCATTCCATAGCCAGGGAGTGGCAGAGCTTGGATTTGAAC CCAGCTCAGTCTGGCCTGGAGCCCAAGTTCCCAACCCCCATGCGGGGTTGAAGGCTACAG GTCAGAGCCTAGGGTGCCATCCTGTGGAAATTCCACCAGGCAGAATTCTGCTGGGCCCGA TCCAGGTGGGAAAGAGGTTTCTGAGGTGGAGCCAGGGCTGCCTGAGCTGTGTGAGCCAAA AGCCCTCCCCCGGCCCACCCAGCCTTGCCCCCATCTGTCCAGCCACCCAAGCTCTGCCCT GTGGACAGCCCCGTCTAGGAGTCAGCACCTGCAGGGAGGTTTCCAGGTGAGGACCCAAGG CCGGGCCCCCAGCCAGGCCCGAAACTCCTGGCTAACAGAGGCCTCTTCACCCCGCGCGCT GGCCAGGGAACCCGGTTGTTTTTTCCTCCAAGTTAAGGAGTGTGGGGCAGGCTGGAAGGC TGCTGGGTAAAGAAGTGGTCAGACCTCAAGACGTCTTCCTCCTTCCTGCTTCTCCTGCTG GACTTCCCCACCACCCAGAGTCCCAGCCCCCACCTGCAACTCGCTTAAAGACCCATGGGA GGGAGCAGATTTAATCCCAGACTAAGCATGTGTGTCCTAGAACTGCTGAAATGTGGAACA TGCTGCCTCTAAAGGTAGTGAGCAATCCTCCAAGGAGGACCTGGCTCGATGCCGCCTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTTGTGGCCCAGGCTGG AGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAGGCAATTCTC CTGCTTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCTGCCACCACACCTGGCTAATTTT TTGTATTTTTAGTAGAGACAGGGTTTCACTGTGTTAGCCAGATTGTCTCAGTCTCCTGAC CTCGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGAATTATAGGCGTGAGCTGCCATG CCCTGCCCATGCCACCTTTCTTTACTGGCCTTGGGGGTAGTTGCGCCATCGGCGCTCTCA ACGCTGCTTGGTGGGTCGGAGTGATGATCTTGGCCCTATTTTGCAGAGGAGGGAACTAAG GCTCAGAAAAGTTATCCTAGCCGTCTTCCGTTGCTGGGAGGCCTGTTGTGTGGACTAGCA GTCAGGACCAAGGGGCAGCCTTCCGGGGGCTGACTTCCGCTCAGCCTGAGGAAGAGCTAA CAGTCCTTGCTGTCCAGAGAGAGAATGGGGGGCCTTGAGTGGCAGTGAGCGCCCCCTGTC TGCAGGATACAGGCTGATGAGTTTTTGGCCAGCTGTAGTCCGTAGAGGCCTGGCGGGTGG CTGGGCTTGGTGGTATTGGGGCCACCCAGCTGGTGAATGGACTCTTGGCTCAGGTCCGCT GATCCAGGTGGGCCCTGTGGGCCTGGAGTGTGCACTCTGCCTTCTGCAAGCTCCCTGGCT CCTCCAGGACTCATCCCATTCAGCACAGGCTCTGTGCCTAGTGGCTGGGAGTACAGAGCT GGGCACAGCCTTGGCCTGCTCCCTAGAGCCCTCCATACCAAGACTATAGGGTAGGGGAGA TGGGCATGGTAAGGACCTCACAAGGCCACAAAAGGTCCGGGGGCTGGATCCATCGCTGGC AGCCTTGACAAGGCTTCTTTTGTGCCTGGCTGGGCAACTCTGCCTGGGTCTGCTCAGATT GCAGACAGAACCTGGGTGACAGAGACAAAGCAGAGCCCAGTGGAAAGTGTCCTTATCGCC TGGGGTCTGATAAGGGCCCCGGGGAGGGGGCTGCCGGCCAGCTCCACAGATCTGAGTGCT GGAGGAGCTGGAAGGGCCGGCTGGGGCGGCTGCAGCAGACGCTTGCCCCCTCCCCCACCC CACTCCCACTCCCCCACCGTGGCGGCTGCTCACTGCACAGTATTGATCTAGTGGCTTCTT ACACCAACCCTCTCAGCAGCCAGTGGGGGAGGGTGGACTGAGATGGCCCAGCGCCCAGAC CCGGCCGGAGATGTCGGGTGTGGGGAGGATTAGGCACCCTTCCCCGTGCTGTGCTGGGCA CTGCTCCTGAGAAAGGTCCAGTGTCCCCAGCCTGAGGCCAAGAGGAGCTGGTGATACTTC AGAAGCAGCCTGGTCCGATAGCCCCAGCTCCAGCCCAGATCAGCTCTGGGACCCTGGGTG AGGCACTCACTATCTCTGAACCTTGCCGTCTGTATTATGGGAATGGTCACAAATCTACCC TTCAGGAGTGGCTGTGAGCATTCAGTGGGGGCTGGAATGGGTGGCTGGCCCATGCCAGAC TCAGGTGCTGCGGTTATGACCTCTCCTGTGTGCCAGGGGCCAGGAACCACCCTTCTGACT CCTGGTGGCCCATATCTCCTTGCCACTTACCTGAAGTGTCAATAAATACGAATGGGATGG GGTCTGGAAGTCAAGAAAGAAATTGGCCAGGCGTGGTGGCTCCGCCTGTAATCCCAGCAA TTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAGTAGTTCGAGACCAGCCTGGCCAC CATAGTGAAACTGTGTCTCTACCAAAAATAGAAAAATTAGCTGGGCATGGTGGCACATGC CTGCAGTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAATCGCTTGAACTCAGGAGGCAGA AGTTGCAGTGAACCGAGATCATGCCACTGCACTCCATCCTGGGTGACAGAGCGAGACTCC GTCTCAAAAAAAGAAAAGAAATGGCTGAGAGAACCACAGTGGCAGGTGCCCCCCACAGCA GCCCACACCCGAAGCTGCAGAAGGGAGGGGCCCTCATGGCCCCAGAGCTCTCCTTCCCTC CCATTGGACAGTGGCCTTGGTGGCAGAAGAAACCAAGTCCTGCTTCAAATTCTGCCGTAC TCTGCCACTTACAAGACTTTCTGAGCCTCAGTTTCCTCACTTGAGAAGCAAAGCTTCACC CGCTTGGCTCACCCCACCTGTGACTCTAGGTGACAGGAAGAGATTCCTTGTATTAGGGAC AGTTTTTACAGTCACCAGGAGGAGCAGCAAGGGCTTGAACACTGGGATTGCGAGTCATGA CCTAGGGACTCATCTGCGCCTTTTGCCCAGTGGCAGCAGAGCAGTTCAGCAAGCTCCCCA CGCTGCCCACCTGCAGGCAGCAGCACCTCTGGCCCCACCCCCGCGTCCCCGCCCCCTGCT GTCTCTTCCCTCCTGTGTTCCCCTGAGCTTGTCCCACTTAGTGTGGCAGGAAGGTGCCAG GAAACTTCTTCCTGGACCCTGGGGAAAGGAGGAAGCTCACAGTCCTATGGGTGGTATTGC TGCCACCCGGGCAGATTTTTGGGCACTTGGCGTTCAGTCACCCTGAGCACACTTTCACCG GTCAGGCACGCTCTGCCAGCTTCGCCTTGTTATCCAGAGGTTTGAGTGGTCTGCGCCAAG GCCGTGTTTCTGCCTACCACCCCCCAGCTTCCCCAATCACTGCCCAAGGGGTGCCCCCAT CCTCAGCCTCTGGCTCTTCACCCCAGGTGGCTGAGGGTTCAAGCTTGGCTGATAGCGAGA TGGAAGCTCTTGACTTCCCTGGAACTCAATACTGTTTCTCTGTGTGGAGGGTCCATAGTG CCCTTGGGACCCTCCTGGCAGCCCCTGAGCTGGCCCCGGGGTTGAAGGGGCCCCTCTGCC GGTCTCTGGAGCTCTTCACTGCAGACAGGCCAGCTCCCTTGCTTTCCTCCCCAGGGCCCC AGCCTGATCCTCCCCCACCCTCCCCTCCTGTCGCTCCGCAGATACCGCTAATCAGCCCCT CCATGGCCCATGATTGCGCTCCCAGAGATATTTTTACCTTATGCAAATAGGTGATGTAGA GGTGCCCTCATCTGCCGGCAGCCAGTCCCCCGCCACTCCCCCGGCCTCCAGCTGCATTCC CTTTGCCGTTAGAGCTGGCTGAGCATCATGGCCTCGCCTTCTAGATCTCCCTAAGCACCT TCAGGGAAACTGTCCTTTAAGGATGGTGGATCTGCTGCTCCACACCTTCCAGCACAGGAG CCTTGGGAGAGGTTTCCCGTGCTTGGGAAGAACAGGGAGGGTACCCACGACATTGCCAGT ATCTTATTGAGCTGTGGGAATGCGCCCTGGGCCAGAGGTGAGGAGTGCTAGTGGAGGGGC CCTAGGGGCCTCCTGCCTCCCTCCACTCTGGGGTCCTGGTGGAGCCTGGCCCATCACCAG TCTTGGGAAGTCCAGACCCATCAGCCTTCTTGGTCAATGATGGGTCAAGGAGGCCGAAGG CTGCCTGCCCCAGGGACAACCACACAGGCCTCTGGTCTCTGTCATTTGCACGTTTGTCGA GCACCATCTGCTGCACAGGGTGGTGTCAGGCACTAGCATGCACTTTACGATTCCTCCTCA CAGGAACCCAGGAGATGAGGCAGGTCCTGGTGCAATCCCCCTTTTACTGATGACCGACAG AGATAAGGAGGTGGAGTGACACCTCGGAAATAGCCAAGCCAGGGTCTGCCTAGCTCCACC TGTCCCCAGAGCTGGTGGTGGTTTCTCAGCTCTGCATTTCCACCTCATTGCTCTGGGGCT GTTTCCCGGGTCCTGAGAGGCCTCAAAGCTGTGGCTGCGCATCCAGTCTGCGACCCTGGC AGCTTCTCCATGCTGCCCCTCCTTGGGTCAGCAGCTGCTCCGTCTATTGGCAGCCTGGGT ACCACTGAGCTGGCCTGCCCAGCCACACCAGGGACCTGGCCGGGTGCCAGGGCTGGGCTG GTGGATGGTACCAGAAAGCAGGTGCCTGAGGTATTAGATGTAACACTGGTGGCAGGCAGA TATGTGAGTGTGATCTGGCCGGCCAATATGGCTGTCAGCCTAAAGCAACCACCGTGTCCA GCTACTGCCCTGCTGCCTGGGCCCTCGGGGTGCAGCCCTCACCTCCCAGAGCACTCAGAG TGCCAGCCTTAAGGGCTTCTCACTCTGGAGACCCCCAGAGACCCAGACAAGTCAGACACA GACACTTGCAGTGTCCAAGGTCCAGGGCAGCCCCTGGCCTCTGCTCACTGCCTCCCATGG CGGTCACCGTGCTCTTGAGGGCTTGAGGACATGAAGCAGGCAGGGCAGAATCCCCTCTCT ACCACAGCTCGGCCTGTCTCTGCCCTCTGGCTTGGCCGTGCAACCTGTGGGGTGTGGGTT CCTTGTTTTGTAGGTGTGTTGGGTCTCCCAGGGAGACTGTAAGTTCCTGAAGGCCAGGAT GCCTCAGCCTAGTCCTCCCATGGCCCCCAGCTGGCACAGAGGGTGTTGAGAAACATCTGG CAGGGTGGGTGGTGGATGGATGAGAAGACTTGCCAAGCAAGCCCTAGAAAGGGAAGGGCA CACCCATTGTGTACCAGCTTTTTCCAAGGCTGTTTTCCTCAAACCTCACCCCTCAGCAGC CCATGGTTCCCCATTCTATAGGTGAGGAAGCTGGGGCCCAGGGAGAATAAAGAGTTTGTA GCAGAGCAGGGACTGGGCTTCAGGCTTCTGTCCTGCCCTTGAGCCTGGATGGGTACCTGC ATCTGTCTACTCCTTCCAGGAGATTTAAGGTCTTTGGGGAGCAGTGCCAAAGAGTAAGGC CTCAAGAGGTCCTGAATCCTTTTGGGTCCTTGGCCTGGTAGGGGCCCACCCCAGAGGGGC TAGTGCAGTTGTCAGCTACTGTGGACACAGCTTCTGTCCTAATGGGGGAAGACAAATAGC AAACACCTAATTGAAATGTACAGTGCATCAGATGGGTGATAAGCATGGGAGGAAGGAGGG GGTGCAGGGTATAGCTGATGGGGCCTTTTTAACGTGTCAGAGAAGACCTCTTAGATAAGG TGGTATTGAAACAGCGACCTGAAGAAAATGAGGATGAAAGCCTCTCAGTTGTCTGGCGGG AGAGTGCATCAGGCAGCAGAGGCAGGAAGTGCAAAGGCCCTGCGGCAGGAGCATGCCCGG CTGGGGTGGATGGTGGTGAGGTCCAGCTAAGGTGGGGTGACAGTGAGGGCCTTGTGGCTC TTGTACAAATGGCTTTTCCTTTGCAATGGGAAATCTTCAGAGGGTTCTAAGCAGAGGATT GACCAGACCTGACCTGGCCTTTGTTCTGGCTCTTATGTGAGGAGAGATGACAGGGAGGAG GGTGCTGAGGCTCACACGGTCACCTGGGCAGGAGGTGATGACGGCTCAGATAGAGCAGCG GTGGTGGAGGTGGTGGGAAGTGGTCGGCACAGGCTGTGCATGTTTGGAGGTAGCAGTGCC AGGACCTGCTGACAGAGTTGCGGCTTCTTTGCAGAACTGGCTGCGGCTTTATGGCTACCT GCCTCAGCCCAGCCGCCATATGTCCACCATGCGTTCCGCCCAGATCTTGGCCTCGGCCCT TGCAGAGATGCAGCGCTTCTACGGGATCCCAGTCACCGGTGTGCTCGACGAAGAGACCAA GGAGTGAGTTCCCCCCACCATCCACACCCCACAGGCACCTGCCTTCCATCTGGCCTGCTC TCAAGAGGGCTCAGCATGTGGAGTTTCCAGAAAAGAGTGGCCTAGATAAGAGATGCCAAA TGGTTTGGTCCTCCATGTCACTTCTGATTGGTTGGAGTGGCTGCCCAAAGCCTTGTATTG AGAAAGCTCCAGGGGCAGAATCCAGGCCTTAGCAGTAAGAAGCACAGTGATTGATTAGTG ATGTCTGACATGGCCAGGGGAGTGTGGAGGTACAGTACAGGAGCTGTGGAAGGGAAATCG TAGCTAGGCATGGCTATGAATCTAACAAGTGACATGACCTAAAGCCATGTCCCTGAAAAC AATGCACAGAGCATAACGTATCCAGGACAGAAGGCCTTGAGCGAACCCTCCATTACTGGG TGATAAGGAGAGAAGGGCTCACCTTGACTGAACCACTCCTGGGCACTCAGTCTTCCAATA CAGGCATTTTGCCCATTTTACTGGAAGTTGAAGCTGAGAGTCCCCCATCCCCACTGTGTC ATAGGAGGGGCGGCTGGGAAGCCCGGAAGTGGCGGAAGTGGCAGTGCCAGAACAGGCAGG TGTGTGGAGGGGAGGCTCCGTGCTCACCCCTCTGTGTCCATGTCCCAGGTGGATGAAGCG GCCCCGCTGTGGGGTGCCAGACCAGTTCGGGGTACGAGTGAAAGCCAACCTGCGGCGGCG TCGGAAGCGCTACGCCCTCACCGGGAGGAAGTGGAACAACCACCATCTGACCTTTAGGTA GGGGGCTCAGCTGCCCAGGGAAGCATCTGCCCCTCGGCAGGCCGAGCCTCAGACCTCCTT TCCCAGAGCCCACCTCGGCGCCCAGCCTTAACAGTCCAGCCCGCTTTCACGCTGATGAGA CCAGCCACACACGCCAGGCAGTCTCCCTCGAGGGAAGGTCAGGACACTTCAAGCTACTTC CACCCTGTCCTTCCCCACCCCCCACCTCCCTGCAGGCAGGGGCTGGCCTCACTGGGCACA GCTGGGCTACTGCCCCAGCACAGACTGCAGCAAGGGATGGGGGATGGCTGGGGTGCAGGA ATCCAGGCATCCATCAAGTGAACAGGCAGCAAGTCACCTGCAGAATCCTTGGATCAGGGG CCCTCATCCTTTTTGCTGAGTTCTTGAGCAAGAAAACCCTCCAGCCAAGTGTGCCTTGAG CCATGTGGTTGTCCCCAAGGGCTCCCCTTCTTGTTCCAGTCTGGCTCTGTCCTGACTCCA AGCTCCATCTCCCAAGGAAGAGTGGTTCCCATGGTCACTTAGACCTCAAGCCCCCAGAGT GAATTCAAGGTCCAACCAGCTAAAATATTCCCTTCAGGTTTAATGTCTAGCACACAGAGC TGAATCTGATTTATATAGGTAAGAGCAGGCCTCACCATACGTCATCAAATGCAGTCTCTG GCTACAACTTACTTCCTCTAATCCTCACTGGAACCCTGTGAAGAAAGTACCACACACACA CTCTTTTCTAACTTAACAGATAAACTGGAAATCGGCCAGGCACAGTGGCTCACACCTGTA ATCCCAGCACTTTGGGAGGCCAAAGTGGGTGGATCAGCTGAGGTCGGGAGTTCGAAACCA GCCTGACCAACATGGAAAAACCCCGTCTCTACTAAAAATACAAAATTAGCCAGGTGTGGT GGTGCATGCCTGTAATCCCAGCTACTTGGGAGGCCGAGGCAGGAGACTCACTTGAACCCG GGAGGTGGAGGTTGCAGTGAGCCGAGATTGCGCCACTGCGCTCCAGCCCGGGTGACAGAG CAAGACTCCATCTCAAAAAGAAAGAAGGAAAGAAACTGGAAATCAGAGAGTCACTTACCC AAGGTCACACAGATACTGTTAGAGCCAGGCCTTGAACTCAGGTCTGCCTGACCCTGGAGC TCAACATTGAGAACTGCTCAGCCTGTTTCCCAAACCTCACTCATTTGCATCCCATTTTCT AGGTCTTTCCCCCAGCCACATAGCACCTGTATTTTAGTTTACTTAATGTCTCTCTTACTT AAAATCAGTTTATTTGCCACAATGCAATCTTAATTTAATGATATCTTCATGATCTCCTGG ATTTGACAAATTCAAATTATGATTTACATCAAAGCAAACTGCCAGTTGATAATGACGGGC TTGTTGGTGACCTTGCGTGCACTCTTGGGAACATGCCAGCAGAGGATAGTAGGCCCTTGG CCCTGCATCCGCTCACTCATCTCCCACCCACCCCCAGCATCCAGAACTACACGGAGAAGT TGGGCTGGTACCACTCGATGGAGGCGGTGCGCAGGGCCTTCCGCGTGTGGGAGCAGGCCA CGCCCCTGGTCTTCCAGGAGGTGCCCTATGAGGACATCCGGCTGCGGCGACAGAAGGAGG CCGACATCATGGTACTCTTTGCCTCTGGCTTCCACGGCGACAGCTCGCCGTTTGATGGCA CCGGTGGCTTTCTGGCCCACGCCTATTTCCCTGGCCCCGGCCTAGGCGGGGACACCCATT TTGACGCAGATGAGCCCTGGACCTTCTCCAGCACTGACCTGCATGGTGAGGACAGCTGGC CAGGGTGAGGGGCAGGGCAGGTGGCCCCGGAGCTGGGCAACAACACCCTGCTGAGTGGGT TCAGCAGCCGCGGGGCTGGGAGGAGAGAGTTCCCCTGTGTTTGTCTCCAGATCACTACAC TCAATTTCAGTCTGTTGTCCCACCATCTCCAAGGGGAGGCGAGAAAGGATGATTGTACCC ATTTCTCAGATGGGGTTGTTGTAGGCCGAAAGAGCTCAGCCTCTTCCAAGAGGGAAGCAA GGGCAGGCTCTCTGGCAGCCTCAGCCTGGAGGGTCCAGGGTGATTGGGTCCTGGGACTGG CCACAGCTGACTGTGCTGCCCTCCTTCTCTCCCCAAAAGGAAACAACCTCTTCCTGGTGG CAGTGCATGAGCTGGGCCACGCGCTGGGGCTGGAGCACTCCAGCAACCCCAATGCCATCA TGGCGCCGTTCTACCAGTGGAAGGACGTTGACAACTTCAAGCTGCCCGAGGACGATCTCC GTGGCATCCAGCAGCTCTACGGTGCGTGGGCTGTGACCAGCGGGCTCTGCATGCCGCTCT CAAGTCCCTGGCCAATGAGGAGTAGGCATTGCTGCCATCCCCATTTTGTAGATGAGGAAC CCAAGGCTCAGTGAGGATTAGTGACTTGCCCACATCATTTGGGGAATAAATGGTGGTACT GGAAATGAAACCCAGGGCAGGCTGCCTCCAGGGCCTGGGCCTCACTCGAGGCTGTGGCTG CAGGCTAGAGGCCTTGAAGGGACACAGGTTCTTCATGACCCTCCTCTCCTCCTCACCCTT GGCAGTATTCTTACTAGACCACAAGTGCCTGGGGGATCCCAGGACCCGCCCCCTTCCACC GTCACTCCCAGCCTGAGCCTGTCACAGCTCTGTCCACAGTGCTGCTGGTTTGTCACTTCC CAGTGGCTTTGAGGAAGTGCCACCCCCCCACCCAGGGCCCACCCGAGAAAGTCTCCAGCA GTGAGGTCCCCTGGGCCAGTTCGGTGGGCCAAGTCCTGCACTCTGTGCCCACACCGAGCC CTCCTCGGGGCTGGCAGCTCCTGCCGTGCTGGGCACTTGACGGGCACCCCTTGCTGCATC CCCAGCAACTTGGAAATGCAGAGTCCAAAACGCCTGAAGCCAGGGCCTGGAGCCTCTGCT GGAGCAGGCTGGCATCCCAAGGGGAATGTCCCCAAGGGGACATGCAGGCAGACACCCTCA GGAGCACAGTGACCCAAGGTCAGTGTGGGGAGATCGAGGAGGGGCTAGAAGGAGGAGGAC CCAGGTCCCACCGAGGATGGAGGCAGGTGTTGGGGAGGGGTCTGCTGTAGATGGACAGGA TTTTACTTTCCGCGTGGGTGGGCCTGTGCTGGGGGCCCCGGGGCCCAGGGTTCTGAGTAG GAACACAGACCTCACTTCTGAACCCCTGCCTCTCTGCAGGTACCCCAGACGGTCAGCCAC AGCCTACCCAGCCTCTCCCCACTGTGACGCCACGGCGGCCAGGCCGGCCTGACCACCGGC CGCCCCGGCCTCCCCAGCCACCACCCCCAGGTGGGAAGCCAGAGCGGCCCCCAAAGCCGG GCCCCCCAGTCCAGCCCCGAGCCACAGAGCGGCCCGACCAGTATGGCCCCAACATCTGCG ACGGGGACTTTGACACAGTGGCCATGCTTCGCGGGGAGATGTTCGTGTTCAAGGTCTGGC CCCGCCTCCCATGCCTGGCCCTGAGCCTTTTCCCTGGCTGCTCTGGGCCCCCTGTCCCAC CCTCACTCAGCAGGCCCCGGGGAGCCATTAAGCCCTCAGCTCTAGATGGGGAGGAATCCA GCCCAAGAGGTTGAGGGACTTGCCCAGGGTCACACAGCAAGCCCTGGTGCCAGCTCCCCA GCTCAGGGCTCTGTTTCTGTGCAGCCCTGGCTTTCCAAGCCACTGCCTGCCTCAGTATCT CAGTGTCCTCCCCTTGGGCCCACCCTCACCTGGGAAGGGGTGGTTTGAGGATGGCACCTC TCCCGGCCAAGGCAGCTTGCCTGCGCTGCCCGCTCACACTATGCCCTCCCCAGGGCCGCT GGTTCTGGCGAGTCCGGCACAACCGCGTCCTGGACAACTATCCCATGCCCATCGGGCACT TCTGGCGTGGTCTGCCCGGTGACATCAGTGCTGCCTACGAGCGCCAAGACGGTCGTTTTG TCTTTTTCAAAGGTGAGCAGAGGTAGGGTTAGAGGGTTGGGCACGCCTCCTGCCATGACC TCTGACCCTGCTGGATCTGAGAGAAGAGGAGGTGAAGGGTTGCATTGCATGTCTGGTCCT GTGCCCCCACTGTGGGCTCACTCTGGGAGGATGAGGACACAGCAGCAAGGCAGGACGGGA GGAAGATAGAGGCTGGAGGCAGGGTTGGACCTGCAACCCGGAAGTGCCTGGCCACCTTGT GCAGCACAGGGCTCAGCCCTGCTTCCCTCTGTCCTTGCCTCTTTGCCTCCTGCAGCCCCA TCCTCATAAGAACAGGTGCCCCCAGCCCACTCCGGGGCCAGATTTCTGTGGTCTGTCTGC AGAGACGAGGTCTTGCAGGGCAGCGCCCCGTGATGGATCCACCAGGGCTCTAACCCCACT GTCCTGAGCTTCAGTGAGGCAGGAGCTCCCTGAGGACAGGGCTGGCACCAAACTAAAAGC AGGGAGCCCTGGGCCACACACTGTGAGGGCTGCAGGTGTGCTCCAGGGACACAGCCCCCA GACCCAGAGGCCAGGCAGTCCCCTCCCCATACAAGAACTATATGTGCGGGGGTGGATGTG CACATGGAAGCGAGGGCTGTGGGTGGCATGTGGCGTGTATGGGTGTGAGCGGGTGACTCT TGCTCACGGGAACAAGTGTGCCTCAGGTATCCATGAGTGCAGCATGTGATGTGCGGGTGA CCTCATTGTATGTTGTCTTGAATATGTAGAGGGGTGTGAGTGTGATTTTGTGGGCCCAGA AGAGCATTCTTTTCCCGCACACACCCCTCAGCCCCAGGCCTGACCTCACTGTGCCTGCCA CCCCTCCTGTAGGTGACCGCTACTGGCTCTTTCGAGAAGCGAACCTGGAGCCCGGCTACC CACAGCCGCTGACCAGCTATGGCCTGGGCATCCCCTATGACCGCATTGACACGGCCATCT GGTGGGAGCCCACAGGCCACACCTTCTTCTTCCAAGAGGACAGGTGAGCAGTGCGTCCCT CCCCTAAGGGGAGAAGGCCCCATCTAGGCCCCCCTCAACCTCAGGCCTACCCAGAAAGAA TCCACTGCCTGTGGGGAACGGGTCCTGGCCCAAGCAGGATCTCTAGGTCCACAGCCTGGT GCTTTTGTTCACAGGTACTGGCGCTTCAACGAGGAGACACAGCGTGGAGACCCTGGGTAC CCCAAGCCCATCAGTGTCTGGCAGGGGATCCCTGCCTCCCCTAAAGGGGCCTTCCTGAGC AATGACGCAGGTACCTGGCCAGCCCCTCCCAGTTTGCCCAGCACCTAATATCCCCTGCTA CACACACCACAGGGCAGGGCTTGCCCAAGGTCACCCGGCACTGTGATGGTGTGTATGGGT GACAAGCTGTGTCACGCTCTGGGCTGGGAGCTTACCTAGCTTGACACCCTGGTCCTTCCT GCATAGTTAAAATTCCCTTTTTACAGACAGGCAAACTAATAAACCAGAGAGCTTGAGCAG AGTGCCCCAAATTCCACAGCCAGGAAGGTGCGGCGTCAGGATTCCAGGCCAGTCCTGCCT GCGTCCGGAGCTGGAGCTTGGAACTGCCCTGATGCCCACAGAGTCCAGCCACCCCCAGGC AATCCCAGGGGAGCCTTGAGCCTGAGTGGGGCAGGCTTGGCTCAGAGTGTTAGGGGTGAA AATCCTCCCAGGGCATCACTCATCTACCTACAAGGAAAGCCCTGTCTCTGTCATTATAAC CAAGAGACAGGGAGCTGTGCCTCTTCTGTTTCTCTAGCAAGGTCTCTAGTGCATTTAAGA AAAACCAGCCAGGTGTAGTGGCTCACGCCTGTAATCCCAGCTCTTGGAGAGGCCGATGCG AGAGGATCGCTTGAGTCCAGGAGTTCGAGACCAGCCTGAATAACATAGTGAGACTCTATC TCTACAAAAACAATTTTAAATCAGCCAGGTGTGGTGACTTGCACCTATAGTCCCAGTTAT TTAGGAGGCTGCGGTCGGAGGATTACTTGAGTCTGGGAGGTCAAGGCTGCAGTGAGCTGT GATCGCGCCACTATACTCCAGCCTGGGTGACTCAGGGGGGACCTTGCCTGCTTTGCCAGT GCTCAGGCCAGTTACACAGCTTCTGTATGTGAGCTTGGCACTCTGCAGCCGCTCTGATCT CTTGTGCTCACCCCTTGATTGAAACCTGGCCCTGCCTGGTATTGATGGGATGCTGGCAAG GTGCCCAAGGTCAGAGAGCCAGCCCAAGGCAGCACCAGGTTCCTTCCGCTCTAGAACAAC TGCGGGGTGCTGTGTGGCCTTGAGCAAGACCCCAAACCTCTGTGGTGTGAGGTGAAGCCA GTTCTGGGAAGGGGCAGCAGGATCCCTGACTGCAGCCCCCAACCCAGCAGGCTATAGGAC CCTTCCAGGCCCTTCCCCAGCTAATGTCAGTCTGGTCAGGAAGCCCAGGGTTCTAGTCGT ACCCTTAGCCCAAAGCCCTCTGAGCCTCAGTCTGGCTCCTGCAAGTTGAGAAGGGGCAGA TTTGAAAATACTCAGGGAAGCAAATGAGAAGAAGGGTGTTTTGAAGCCCTCAGCATGTCC TGGCCTTTGATGGTTCTCACTGGTGGTTCGGCTCAACCTGAAGCCACTCTGGCCTCCTTG CCCCTGCAGCCTACACCTACTTCTACAAGGGCACCAAATACTGGAAATTCGACAATGAGC GCCTGCGGATGGAGCCCGGCTACCCCAAGTCCATCCTGCGGGACTTCATGGGCTGCCAGG AGCACGTGGAGCCAGGCCCCCGATGGCCCGACGTGGCCCGGCCGCCCTTCAACCCCCACG GGGGTGCAGAGCCCGGGGCGGACAGCGCAGAGGGCGACGTGGGGGATGGGGATGGGGACT TTGGGGCCGGGGTCAACAAGGACGGGGGCAGCCGCGTGGTGGTGCAGATGGAGGAGGTGG CACGGACGGTGAACGTGGTGATGGTGCTGGTGCCACTGCTGCTGCTGCTCTGCGTCCTGG GCCTCACCTACGCGCTGGTGCAGATGCAGCGCAAGGGTGCGCCACGTGTCCTGCTTTACT GCAAGCGCTCGCTGCAGGAGTGGGTCTGACCACCCAGCGCTCCTGCTAACGGTGCTCAGG GGGCGCCTGTGGTTCTGAGATGGCTCCCAGGGGCTCCCTCCGCCCCCAGGTAGGGGCCCC TCTCAGCCCTCACACACCCTGTCTGCCCCGCCCTCATTATTTATGTCCAGGTGTTTGTTT TGTTTTGTTTTTGGCACCTTACTTGACCATTTGTTTCTGTTTCCCCGACTGGGGCAGGGT GTTTAGAATTTTCTAAATGTAGTTCTGCTCCAGACAGGGAATTAGGCCCCCATCATCCTC TGGCTTGGCCACAGCCAGGGGAGCAGAGGGGCAGAGGCCCACATTGGAAGAGCAGCACCT CCTCAGCCTGAACCCCAGGGCTGTAACTGCCAGGCTCTCTTTGCCCAGTTGGAGACTGTC TGGCCCCCCTGGTCCCCTCCTTCCCAAGTGAGTCTCTCTGGGCCTTAGGAAGAGCCTTCC ACCCAGGGGCAGCCCCAGGCCAAAGGGGACCTGGAAGGGAGGTGGGCCGTGGCCCTTGAG TCCCCATTGAGGCTTGGTTCCTTCCCAATCCAGTGGACTTCGCAGTCCACTTCTGACAGC CTCAGTGACCCTGGCTCCTTGTGCCAGAGAACCCAGCCCACCCCCGGCAGCAGCCCCCAG CTCCCACCTCCCCTTGGGCCCACACCTCCTTCCCTCTCTGGAGAAAGGGCCCTGGGCCTG CCTCACCACGGACCAAAGGGAGTCTGCCAGGGCCCCTCTCCCCAGGGAAGCAGCAGCCTC GCCCCTGGCAGAGATGCCTCCCTGAGCTAGAACCCTCTGTTCCTTCCCTGTGCCTCCTCC CTCCCTCTCCGACTCACACCACTAGCCTCAGGGGTCTGAGCTCCAGCTCCTTTGGGCTTC AGCTGCCAGTGTCCTGAGCCCCAGGGAGAGGGGGCTGGTGGGTGCCTAGGCCTGGGCAGT GGATGGCCGTGAATGGGTGCCCACAGTGTCAGGCACTGGGCATGAGGGGTTCCTCCCCTC CAGCTCCCTGTGCCCCCAGGGTCCTGGGAGGAGAGACACTGGTGGGGATAGGCCAGCCGC GCATCAGACTGTGAACCCCACGAAGGAGCCCATTGTGGCCTAAGAGGCTGCCCTCCTGTG CTCAGCCCTGAGGACAGATGCCTCCTTCCTCTTTTCCTTCCCAAAGCAAGCAAGAGGCCG TGGCTGCTGTGGGAAATGGTACTGTACAGCTGGCTCTACTTCCCCATGGCCCTGAGCGAG TGGAGTCTGCCACCCAGGATCCCCAAGGCACTTGAGGGGGAAGGATTCTGCTGGCCTCTG CGAGTGGTTTCTTGTGCACTGGCACCAAGTGCGGGTCCGGCAGCTTCTGCCCCCTGCAGA ACCGGAGAGCCAGCTAAGGGGTGGGGCTGCGGGGGTTCCGTGTCCACCCCCATACATTTA TTTCTGTAAATAATGTGCACTGAATAAATTGTACAGCCGGCAAA OMIM ID 602261