| Entrez gene ID | | 4199 |
| Official gene symbol | | ME1 |
| Full name | | malic enzyme 1, NADP(+)-dependent, cytosolic |
| Aliases | | ,HUMNDME,MES, |
| Gene summary | | This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq] |
| Location | | Chromosome: 6 Locus: 6q12 |
| Gene position | | 84140938 - 83920108 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 220831 bp |
| Gene sequence |
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| OMIM ID | | 154250 |
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