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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ME1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4199
Official gene symbolME1
Full namemalic enzyme 1, NADP(+)-dependent, cytosolic
Aliases,HUMNDME,MES,
Gene summaryThis gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q12
Gene position84140938 - 83920108  Map Viewer
Gene orientationminus
Gene size220831 bp
Gene sequence
OMIM ID154250