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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MCM6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4175
Official gene symbolMCM6
Full nameminichromosome maintenance complex component 6
Aliases,MCG40308,Mis5,P105MCM,
Gene summaryThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q21
Gene position136634011 - 136597196  Map Viewer
Gene orientationminus
Gene size36816 bp
Gene sequence
OMIM ID601806