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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LUM (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4060 Official gene symbol LUM Full name lumican Aliases ,LDC,SLRR2D, Gene summary This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq] Location Chromosome: 12   Locus: 12q21.3-q22 Gene position 91505542 - 91497232  Map Viewer Gene orientation minus Gene size 8311 bp Gene sequence >LUM:complement(53640538..53648848):Length=8311 ACAGTGAGCTTCCTTATTTGAAGCAGGACTCAATTCTTGGTTAAAAGCTATGGTATTTGA GCTAGTTAAACACATATCTCTCTCCCATTCCATAGGGAATGAGCTGGGCTGTCCTTTCTC CCCACGTTCACCTGCACTTCGTTAGAGAGCAGTGTTCACATGCCACACCACAAGATCCCC ACAATGACATAACTCCATTCAGAGACTGGCGTGACTGGGCTGGGTCTCCCCACCCCCCTT CAGCTCTTGTATCACTCAGAATCTGGCAGCCAGTTCCGTCCTGACAGAGTTCACAGCATA TATTGGTGGATTCTTGTCCATAGTGCATCTGCTTTAAGAATTAACGAAAGCAGTGTCAAG ACAGTAAGGTAAGTGCTGTTTTAACTATTGCACTGGGGATGTTAACTGTTTGGGACAGCG TTTTTTGTAACAGGAACAGGAAAAATTCCAGAGCAATTTTGCCAATTGCTATTCAACAGC AAATCCACAGTTCTGAGCATTTAGTTTCACATTTTGTTAATATGTTTTCCATGATTTATA GATTTGAGATTTTATACAGTATATGCTGTATTGCTTGGCAAGAGAAGTTATAAAAAGTTT CAAGGTTAGAATGAGAAAATAGTTAAAGTAGACACAGTGAAAAAATATAGAAATTAATAT GTTTGTTATGTATGCTAGTTAGTTATATATGTTAGTATTGGACCCTAATACTGGAGCAAA GAAAAGTCATTTTAATCAGCATTCAAAATATCTTTTAATAAGCATATTGTGACAATTTGT TATAATTTACAATAAACGTTCTATGTTATAAAACATGAGCTAAAAGATTTAGGAACTCTT ATGGATTATTTATTTCTGTTTTGTTAATTTAAAAAATTTGTTTCTTGGATATATGCCTTA AGGAACGAGTTTTTTAAAAAGTTCTGGGAAATGATTTCGTTTTTGAAAACAGCATTTTCT CTATAGCCACAGGTATTTGAAAAAACTGAGGGTAGTACAGTGTGATTTTGCCTCATAGTG GAGTCATTATATGGTTGCAAACTCTCATTCAATTCAGCATCCTTGTTTTTACTTTGCCAA AAAATATGGAAGCATTTTTCATTACTATTTAATACTCACATTATAGTTGCCATATTTTGG TGTATAGTAAATTTAAAATAGCTTATTAATAAAGCAAGACAAATCTTTACAGTATTTACA TTCTATAACTTAAAATAACTCTGGGAATATGTCATCACGTTCTTTTTAGTGCTATGCAAT TATTATTATGGCCAAGTTCTGTCAGCAAAATTAAATGCCCCCATTAAAATCTTAGAGAGT AATTTACTGAGAATCTGGCTACATGTTACCTTATGTCAGCAATCAAAGTATTTCTAAAAG CTGTTTTATAACGTTCCATCTGATCTGAAATAAAGTGCCTTACAATTTCAAATTAAAACA AATAAAAGACGTTTTCAGTTTCTAACCCCAAAGATCCTGCTTATCCCAAACTACTTTGAT CCAAAAGCTTGTAATCATACTTTCATAGAAAGATATAATATTCTCAGTTATCTATTAGAA TGTAGATCTTTCGTCACATTAATGATTTATCTCCCAGGGCTACCAACTTTGCCTCAGCCA CAACTGTTCACTCTATAAAAGTCTAACTCTTATATTCCAATTTTCCCATATCTAAATTGC TGCACCTAAGACATTGAAATGTACTTTTTTGAGCCTCACCTTAGAAACATGTTCCTATGA GAAGATAACTGTTACACATTATTTCAAATTCATATTCTCAATTGAATAATTTACTAGATA GTTCTAACACCAGTATTAAATCCAAACTTTAAAAACATCACACCTCTCTCCCACCTCCAT TCTGTGAGGCCACTAAAAGCCAGATATGCAAACCATGGCATCTTCGATTTTGGCATGAAG AAAGTAGAGAACTTGTGAGTAATTGAGAGAGACTATAACTCTAATTGAAAACTTGGAAAA TACTATCTTTCTCTACCTGTTGAATCTCTTTCCAGAAAGAGAAACCTTCAGAATGTGTGA CATTTTCCTGATAAACATTAGCAATTATTAAATATTACTAATATTTTGTTTAGTAAATAG CTAATTTATGAAATATTAGTTCCAGAACACAGTTTTGCAATGTGCTTTAAAAAGTGTAGA ATGTTAAGCACAACATGAACTAGTATGCATGCACACCAGCACCAAGAATTCTGTTCTCCT TCCTCAGAACCAACAGTAACCAGACACTTTTAAAGGAATGTGCCTTCCATTTCCCTCCCA CATACAAGCAAAACCTCAGGTTGCCCATATTCCCGTAAGGATCTTCTTCATGAGTCATTT TAATGATGTCGAATGGTAGGGTAGAGTATACAGTTAAAAACTGTCTTCTCATTCTCTTTT TTTGAGAGATGATCTGAAGCAGTAGTCTAATTCGGTGGTCAATGAACACCACCCAGAAAC CTCTTACAGGAAGGCATTTCATTAAGGAAGAGCCTGGAGATTGACTGGAACAATTAGGCT GGGCTCGCCCAGAAGGGGGCGCACGTGTACGCAATCTAACCTGAAAGCTGCTCACTACAT AGTTGTAAACATACACCTTTGTCCTCATACCTAAATAAAAATTTAAAAGACGCTGTTAGA TGCACTAAAAATAGCTATAAAATAACAAAATGCACATTTTCTAATGAATTTAATGTTGCA AATTGAATGTCTTTTTCTTGAAAGTATATATTTTTTTAATTAATAAATGTTTCATCTTTA TTTAGGATTCAAACCATTTGCCAAAAATGAGTCTAAGTGCATTTACTCTCTTCCTGGCAT TGATTGGTGGTACCAGTGGCCAGTACTATGATTATGATTTTCCCCTATCAATTTATGGGC AATCATCACCAAACTGTGCACCAGAATGTAACTGCCCTGAAAGCTACCCAAGTGCCATGT ACTGTGATGAGCTGAAATTGAAAAGTGTACCAATGGTGCCTCCTGGAATCAAGTATCTTT ACCTTAGGAATAACCAGATTGACCATATTGATGAAAAGGCCTTTGAGAATGTAACTGATC TGCAGTGGCTCATTCTAGATCACAACCTTCTAGAAAACTCCAAGATAAAAGGGAGAGTTT TCTCTAAATTGAAACAACTGAAGAAGCTGCATATAAACCACAACAACCTGACAGAGTCTG TGGGCCCACTTCCCAAATCTCTGGAGGATCTGCAGCTTACTCATAACAAGATCACAAAGC TGGGCTCTTTTGAAGGATTGGTAAACCTGACCTTCATCCATCTCCAGCACAATCGGCTGA AAGAGGATGCTGTTTCAGCTGCTTTTAAAGGTCTTAAATCACTCGAATACCTTGACTTGA GCTTCAATCAGATAGCCAGACTGCCTTCTGGTCTCCCTGTCTCTCTTCTAACTCTCTACT TAGACAACAATAAGATCAGCAACATCCCTGATGAGTATTTCAAGCGTTTTAATGCATTGC AGTATCTGCGTTTATCTCACAACGAACTGGCTGATAGTGGAATACCTGGAAATTCTTTCA ATGTGTCATCCCTGGTTGAGCTGGATCTGTCCTATAACAAGCTTAAAAACATACCAACTG TCAATGAAAACCTTGAAAACTATTACCTGGAGGTCAATCAACTTGAGAGTAAGTAAAAAG CTGTTCCTGTGTTTGATGTGTGCTCAAGTGTTTAAATACCTGGGCTGCACAACACAGATA TTGCATCTGGCTCCATTAAAAAAACAAAATGTCGCCCGGGCGCTGTGGCTCATTCCTGTA AATCCAGCATTTTGGGAGGCCGAAGTGGGCGGATCACCAGGTCAGGAGTTGAGACCAGCC TGGCCAACATGATGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGT CGCACTTCTGTAATCCCAGCTACTCAGGAGGCTGAGCCAGGAGAATTGCTTGAACCTGGG AGATAGAGGTTGCAGTGAGCCGAGATCGTGCCACTGTACTCAAGCCTGGGCAAGACAGCC AGATTCTGTCTTGGAAAAAAAAAAAATGTCCACAAAATATCCCTCTACTTCAAACAAAGA ATAATTCTAGCTCAATCATATATCCAATATCCAGCCTTTCTTTGGTGTATCCAGATAAGG AACAATTAAGGTCACAGAATTTAATATGTAAGTCTTCAAACTAAAAATTCCGGGCCAACT CATCCTGCTGTGTTACCTCCTCATATATATCTCTTATTATTTTCTCCTTTATGGCTTAGA TTTGTGTCCTACATTTATTTTTTGACAAGATCTAGATGAGGGAGGAAGAAATGAGTTCAA AAGTGGCACAGTTGGCAAACTCCATAGCCACAAAGAAGCCCATATTGTCCCTCCCTCCCT CCCTCTCTCTCTCTTTTTCTTTCTTCCTTCCTTTCTTTCCCTTTCTTTCTTTCTTTCTTT CTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTCTTTCTTTCTTTCTTTCTTTCT TTCTTTCTTTCTTTCTTTCTTTCTTTCCTTTCTTTCTTTCTTCTTTCTCTCTTTCTTTCT TTCTTTTTCTTTCCTTCTTTCTTTCTTTCGTTTTCTTTCTTTCTTTCTTTCTTTTTTTTT TTGACAGGGTCTCACTCTGTCGCCCAGACTGGAGTGAGGTGGTGCAATCTCGGCTCATTG CAACCTCCACCCCCCAGGCTCAGGCGATTCTCCCACCTCAGGCCACCACCACCACCAGGC TAATTTTTATGTTTTTAGTAGAGATGGGGTTTCACCATGTTAACCAGGCTGTTCTTAAAA TCCTGACCTCAACTGATCCATCTGCCTTGGCCTCCCAAAGTACTGGGATTACAGGCGTGA GCCACTGTGCCTGGCCCCATATAGTCTCATGGTCTTCCCTGACATCAACTACTTGGGACT CACCATGTTACTCTGCTGTCATGATCATCATCTGCCTCTGTTATCTCTGTTATGGTGTGT GGCCATCACAGTGCTCTGGAGGACTGTGAAGAAGATTAAAGAGAAAAAGAAATATGATGG GAGATTCTAACATCTTTTTTTTTTTTTTTTTTTTTAGAAGAAAAATAGTGTTACAGAGCT TTTTTTTTCTTGGGTACAATCCTGCCCCTCATTTGATATTTCCACACTTTCTCTTTCTCC TCTCTTTATTTTTCATTTATCTTCTGGATGAAGTTTGATCTGATGCATTTGGACTGCTTA TGCACTTATGTGGTCTTCAGGGACATTCTTCAACTTAAGCAGTATAGATTCCAATGGGAA ATTGAAATCCACCATTTCCTACCAGGATAACTCTGCCATTAATCTTTGGCAGAGCTTGGT AGAAGAGAAAAACCATGATTCACAGATAAGGCTTTCTAAATGAAAAAATCAAGCAGGAAA CATTGATTCACATATAAAGTAATAATGTCTGCAAAATAATCTATTGAATTTGAACATCTC TACATGATGAAAATTGGTTTTCTGGCCATGCTGAATAAAGGTATTGCTGTCAGAAAATAT TACAATATATTTTATGCATATGATGTTTGTTAATTCTGCCAGTTTCATATAACCTCTAGT AGGGTTAAACGTTTTCATAAAGAAGACCATACTCGCCAACTCTGAAGCTCCACATGTTCT TTGTTGTTTCTGAAAAGCAGCCAAGGTAAGGGTTGGTGCTGTTTGACTGTCACACAATAC ACAGTCAGGCTAACACAGCTAAACCCCTCTTGTTGTTTCCAGTGGAAAATTCACTATGTG GCCATATGTGATTCCTCATTTTAAACATATGTGGTTAGGAGGAAGGATACTCTCTGACAG ACCAAAATGCTAAAGGAATTTACGATGCTTAAGGGATGACGGAGTACATTAGATTTGGTG GGTAGAGATTATTCGTAAGAGCAGGGCTACTTCTTTCTCTGAAACAAAGAAGGATACAGA AGTAGGCACATTTGAAGGTATACATTGCATGAGTAAAGGATGGAAGAGAGGTCTATGGGA GAAAGGCCAACGGCCTGTCAGTGCCAAGCTGAGATAGAAACCACAGTGCCCAGTACATAG TGGTCATTTGAAAAGGTAACATAATAGTTTCCTTTCTTTCTTCCTTATCTTTGTACATTT AGTCAGGTATTCTCCTTGTCTTTTTATGTATCACCTCAGTTTAGGTTATTTTGCCAGATA ATAATCAACTATATCAACATTTCACATTCACTTAATACAGAAAGTTCCCCTCAATGTTTT TTTCTAATATTAGGGAATATATAGCCAAAACAAACTGTTTTCTATTTCAAACTTGCAACT CTAAGCATTAGCCCAATCAGAGATCTTCCTAGTGTAGAGTAATTTAGAAAGACAGCAAAA TCAAAAGGATATTAGTCATTATTTAGGACATACTATGTACTAGTATTGTGTGAAGTGCTC TACACAACTTAATTTAATCTTCATGCAACACGGTAAGATAGATGTGTTATTTCTAACAAG ATCAGATAAGTGTTCCAGTGTTGCCCACCTGGGTAAGTGGCAGAGGTAGAATTCCAAGAT GGGACTATGCCCATCTTCTTTCCATTTTTCCTCACTTTCTCAAATGTTGGTACCATAGAA AAATCCCTGGAATTAACTGATGAGTTATTTTAAAAAGCATGTGTGTTTGGGGTTCCACTG AAGTCTTTGTTAACTAGAGTTTGAAAATGAAAACAAGATAAAGGACTTGAAAATGTTAAT CTAAAATAGACATAGGCAAACATAGTTTCTGTGTATACACAGGTCAGTCAATTCAGTAAC ACTCTTGGTTTCTATTACAAAGTAAGTCAGTGTTTCATTTGTGGCAGCTTTTTGACCATG GACAAAAATAAACAAATAAACAAAAACATGAGTTCAGATGGTGGACATGCCATGATTAGG TTTTTGCCTTAGAATTTTGATCATTGCTATGGTGTGTGATTGCTGGAATGATTTGGTTTT TGTCTTGGAATTTTTATCATGGTCATGGTATGTGGTTGCTAGAAAATTCTTTATAGATCA TCTAGTTAACCCTTCTTATTTTTAGATGTAAAACCAAAGAGTACTTATACTGAGATTGTT CATACAACAATGGGATCCATTTATATTTCTTCAGGTTATACTATTTCAAAAAAGTTGTTA GATAATATGACACACTTATTGAATGCCTTTTTAAAAACAACTTCTAGTAATAAAATAAGT TCTGTTATTTAAAATATTCCACTGAATATCTTGATCTACCATGATTACTCTTTACTAAAT GTTACTGTGCCATTTTGGTAGCCTGAAATATGCCTTTAATGGTTGCAAATTCAAACATAT ACTATATTATGACTTTTCTAAATGGGAAGAGGTCCTATTTTATAATATATTAAACATAAA TTTTTTGTATTGTTTTGAGCCAGTGTACTGAAAAATGATTAATGTTTTCTATTCTTTAAT TTTTAGAGTTTGACATAAAGAGCTTCTGCAAGATCCTGGGGCCATTATCCTACTCCAAGA TCAAGCATTTGCGTTTGGATGGCAATCGCATCTCAGAAACCAGTCTTCCACCGGATATGT ATGAATGTCTACGTGTTGCTAACGAAGTCACTCTTAATTAATATCTGTATCCTGGAACAA TATTTTATGGTTATGTTTTTCTGTGTGTCAGTTTTCATAGTATCCATATTTTATTACTGT TTATTACTTCCATGAATTTTAAAATCTGAGGGAAATGTTTTGTAAACATTTATTTTTTTT AAAGAAAAGATGAAAGGCAGGCCTATTTCATCACAAGAACACACACATATACACGAATAG ACATCAAACTCAATGCTTTATTTGTAAATTTAGTGTTTTTTTATTTCTACTGTCAAATGA TGTGCAAAACCTTTTACTGGTTGCATGGAAATCAGCCAAGTTTTATAATCCTTAAATCTT AATGTTCCTCAAAGCTTGGATTAAATACATATGGATGTTACTCTCTTGCACCAAATTATC TTGATACATTCAAATTTGTCTGGTTAAAAAATAGGTGGTAGATATTGAGGCCAAGAATAT TGCAAAATACATGAAGCTTCATGCACTTAAAGAAGTATTTTTAGAATAAGAATTTGCATA CTTACCTAGTGAAACTTTTCTAGAATTATTTTTCACTCTAAGTCATGTATGTTTCTCTTT GATTATTTGCATGTTATGTTTAATAAGCTACTAGCAAAATAAAACATAGCAAATGGCATC ACTGTGTTTGACTTCTTGTGAAATTTCTGTACTTTGTATATAAAATACATAAAACAATAG ATTAGAAATCAAAAGATATCTCTGGCCTGCA OMIM ID 600616