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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LTBP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4052
Official gene symbolLTBP1
Full namelatent transforming growth factor beta binding protein 1
Aliases,MGC163161,
Gene summaryThe protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p22-p21
Gene position33172369 - 33624576  Map Viewer
Gene orientationplus
Gene size452208 bp
Gene sequence
OMIM ID150390