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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LTA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4049 Official gene symbol LTA Full name lymphotoxin alpha (TNF superfamily, member 1) Aliases ,LT,TNFB,TNFSF1, Gene summary The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis. Location Chromosome: 6   Locus: 6p21.3 Gene position 31539876 - 31542098  Map Viewer Gene orientation plus Gene size 2223 bp Gene sequence >LTA:3049492..3051714:Length=2223 AGTCGCCTGAACCCCCAGCCTGTGGTTCTCTCCTAGGCCTCAGCCTTTCCTGCCTTTGAC TGAAACAGCAGTATCTTCTAAGCCCTGGGGGCTTCCCCGGGCCCCAGCCCCGACCTAGAA CCCGCCCGCTGCCTGCCACGCTGCCACTGCCGCTTCCTCTATAAAGGGACCTGAGCGTCC GGGCCCAGGGGCTCCACACAGCAGGTGAGGCTCTCCTGCCCCATCTCCTTGGGCTGCCCG TGCTTCGTGCTTTGGACTACCGCCCCGCAGTGTCCTGCCCTCTGCCTGGGCCTCGGTCCC TCCTGCACCTGCTGCCTGGATCCCCGGCCTGCCTGGGCCTGGGCCTTGGTGGGTTTGGTT TTGGTTTCCTTCTCTGTCTCTGACTCTCCATCTGTCAGTCTCATTGTCTCTGTCACACAT TCTCTGTTTCTGCCATGGTTCCTCTCTGTTCCCTTCCTGTCTCTCTCTGTCTCCCTCTGC TCACCTTGGGGTTTCTCTGACTGCATCTTGTCCCCTTCTCTGTCGATCTCTCTCTCGGGG GTCGGGGGGTGCTGTCTCCCAGGGCGGGAGGTCTGTCTTCCGCCGCGTGCCCCGCCCCGC TCACTGTCTCTCTCTCTCTCTCTCTTTCTCTGCAGGTTCTCCCCATGACACCACCTGAAC GTCTCTTCCTCCCAAGGGTGTGTGGCACCACCCTACACCTCCTCCTTCTGGGGCTGCTGC TGGTTCTGCTGCCTGGGGCCCAGGTGAGGCAGCAGGAGAATGGGGGCTGCTGGGGTGGCT CAGCCAAACCTTGAGCCCTAGAGCCCCCCTCAACTCTGTTCTCCCCTAGGGGCTCCCTGG TGTTGGCCTCACACCTTCAGCTGCCCAGACTGCCCGTCAGCACCCCAAGATGCATCTTGC CCACAGCAACCTCAAACCTGCTGCTCACCTCATTGGTAAACATCCACCTGACCTCCCAGA CATGTCCCCACCAGCTCTCCTCCTACCCCTGCCTCAGGAACCCAAGCATCCACCCCTCTC CCCCAACTTCCCCCACGCTAAAAAAAACAGAGGGAGCCCACTCCTATGCCTCCCCCTGCC ATCCCCCAGGAACTCAGTTGTTCAGTGCCCACTTCCTCAGGGATTGAGACCTCTGATCCA GACCCCTGATCTCCCACCCCCATCCCCTATGGCTCTTCCTAGGAGACCCCAGCAAGCAGA ACTCACTGCTCTGGAGAGCAAACACGGACCGTGCCTTCCTCCAGGATGGTTTCTCCTTGA GCAACAATTCTCTCCTGGTCCCCACCAGTGGCATCTACTTCGTCTACTCCCAGGTGGTCT TCTCTGGGAAAGCCTACTCTCCCAAGGCCACCTCCTCCCCACTCTACCTGGCCCATGAGG TCCAGCTCTTCTCCTCCCAGTACCCCTTCCATGTGCCTCTCCTCAGCTCCCAGAAGATGG TGTATCCAGGGCTGCAGGAACCCTGGCTGCACTCGATGTACCACGGGGCTGCGTTCCAGC TCACCCAGGGAGACCAGCTATCCACCCACACAGATGGCATCCCCCACCTAGTCCTCAGCC CTAGTACTGTCTTCTTTGGAGCCTTCGCTCTGTAGAACTTGGAAAAATCCAGAAAGAAAA AATAATTGATTTCAAGACCTTCTCCCCATTCTGCCTCCATTCTGACCATTTCAGGGGTCG TCACCACCTCTCCTTTGGCCATTCCAACAGCTCAAGTCTTCCCTGATCAAGTCACCGGAG CTTTCAAAGAAGGAATTCTAGGCATCCCAGGGGACCACACCTCCCTGAACCATCCCTGAT GTCTGTCTGGCTGAGGATTTCAAGCCTGCCTAGGAATTCCCAGCCCAAAGCTGTTGGTCT GTCCCACCAGCTAGGTGGGGCCTAGATCCACACACAGAGGAAGAGCAGGCACATGGAGGA GCTTGGGGGATGACTAGAGGCAGGGAGGGGACTATTTATGAAGGCAAAAAAATTAAATTA TTTATTTATGGAGGATGGAGAGAGGGGAATAATAGAAGAACATCCAAGGAGAAACAGAGA CAGGCCCAAGAGATGAAGAGTGAGAGGGCATGCGCACAAGGCTGACCAAGAGAGAAAGAA GTAGGCATGAGGGATCACAGGGCCCCAGAAGGCAGGGAAAGGCTCTGAAAGCCAGCTGCC GACCAGAGCCCCACACGGAGGCATCTGCACCCTCGATGAAGCCCAATAAACCTCTTTTCT CTG OMIM ID 153440