| Entrez gene ID | | 4017 |
| Official gene symbol | | LOXL2 |
| Full name | | lysyl oxidase-like 2 |
| Aliases | | ,LOR2,WS9-14, |
| Gene summary | | This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq] |
| Location | | Chromosome: 8 Locus: 8p21.3-p21.2 |
| Gene position | | 23261722 - 23154410 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 107313 bp |
| Gene sequence |
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| OMIM ID | | 606663 |
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