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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LAMA2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3908
Official gene symbolLAMA2
Full namelaminin, alpha 2
Aliases,LAMM,
Gene summaryLaminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q22-q23
Gene position129204286 - 129837711  Map Viewer
Gene orientationplus
Gene size633426 bp
Gene sequence
OMIM ID156225