Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ITPKA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3706 Official gene symbol ITPKA Full name inositol 1,4,5-trisphosphate 3-kinase A Aliases ,IP3-3KA,IP3KA, Gene summary Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region. [provided by RefSeq] Location Chromosome: 15   Locus: 15q14-q21 Gene position 41786122 - 41795747  Map Viewer Gene orientation plus Gene size 9626 bp Gene sequence >ITPKA:12576679..12586304:Length=9626 GGAAATGACCCTGCCCGGGGGCCCAACGGGCATGGCGCGGCCGGGGGGCGCGAGGCCCTG CAGCCCGGGGCTGGAGCGGGCCCCGCGCCGGAGTGTCGGGGAGCTGCGCCTGCTCTTCGA GGCGCGCTGTGCGGCGGTCGCTGCGGCCGCCGCCGCGGGGGAGCCCCGGGCCCGCGGGGC CAAGCGGCGTGGGGGACAGGTCCCCAACGGGCTTCCGCGGGCTCCCCCGGCCCCGGTGAT CCCTCAGCTGACCGTGACAGCCGAGGAGCCCGACGTGCCCCCGACCAGCCCTGGGCCGCC GGAGCGGGAGAGGGACTGCCTCCCGGCAGCGGGCTCTTCGCACCTGCAGCAGCCGCGCCG CCTTTCCACCTCGTCGGTCTCCTCCACTGGCTCCTCGTCGCTGCTCGAGGACTCGGAGGA CGACCTGCTGAGCGACAGTGAGAGCCGGAGCCGCGGCAACGTGCAGCTGGAAGCGGGCGA GGACGTGGGTCAGGTACGGGCCGCGGGGGCGGGGCCAGCGCCGGGCGCGGGGGCTGCACG GGGGACCTGGCTGGGTGCTCCCGGAGGACCCGCTCCTGTCCATGCTCCCTCCAGCGGAAG GTCCTGTTCTCGCGGTTTAGGAGGAATCTGGGGGTCAGAGGGAGGCGCCTGGCCGACCTC TCGCCTGGGCAACTTTCACCTCGGCTCCGCCGGCGGGTCGTGGCGCTGGCCCTGGGGCGT CTAAGAAGCGGGGCGAGGAGCAGGCGACCCGCCGCGGGGACTGGGCGAAGCGGGGGTAGC GGACCTTGTTGGCTGTGGGTTAGGACAGGAGGGATCGGAGGGGCTGAGCCTTGCCGGGTG AACCCTCGGAAGGAGAGAGGCGAAGGAGAGTTTCCCTTACCCCCCGCCCCCTCTCCGGTG CCGCGGCCGCACCCCCGCCGTTGCCACGGTTTCCCTCTCCTGAGTGGGAGTGGAGCGGCG CTCCAGGCTCTGCTCGGGAGCCGCTGCCGTCTGCTCCCAGCGCCCGCACGAGGCGTGGAC GCAGGGGAGGGAGGGGCGTGGGCCTGGGAGCTCTGGCTGGGAGCGGAACGCAGCCCACCC AGTGCGCGCCCTGCCTCCCATCTTCCCGGCTCGCCGCTCCTGAGCGCGGCAGAGAGGGGC GGTAAACTGAGGCTGCAAGGGGGCAGGATCACTCTGCTAGTCTCTGCCTCTGATAGCCTG GGTGTTCTGGGACCAGGTCTGACCCTCGGAAAACACAGCCCTGGGCACTGTTAAGTCATT CCTGACGCCCGCCACTTAGGGATGTGCGGCTCCCGGGACACCCTCCTTGTTCCCCTCGTT TTAACCAAGGCCAAATACCTTGAATAACTGTCCGTGGTCAGCGCGAAGGACTTTCTTTAG ATCCACGTTTCGCAAGTGTCCCTGAGGCCGAGGAAGAGGCGAGGGGCGCCCCCGGCCTCG GGCGTCTGGGGCCTGCCCATAAGTCCGGGTCGGCGCGGCGGGGCGGGGAGAGCTGTGGCC GCGCGCCTGCTCCGCCGCACAATCGGCTGGGACAAGGCAGGGAAGCTGTGGCGACCTGCA GGGGTTCACAAGCCCGGAGGCCGATGGGGTTTGTCAGTGACACCAGAGGGGAAAAGCCTC ACAGAGCAGGAACACCCCCCGCCGCCAGGTGCTGGGTGCGCCGGCTCGGTCACTAGCCTG CCGCTTCCCCTTCTTCCCCGGTGGTCAGAGCAGCCCCGGACCCAGGATCGTTTCTGGGGT AACCCTTGCCTAGGTCGGGGGGCGGATGCCGGGGCTTCCCAGGATGTGGAGTGTGGGGCA GTGAGAGGCCCCCCGCCCCGCCTCTTCGGAAAAGCCTGAGCAGCAGCTCCCGGGGCGCGG AAGCTCTGACACCTGAGAGCCGGTGCAGGCGAAAGGGCGCGAAGCGCGGGCGCGTCCCGC TTCCCTCTTCCGCCCGCAGGGACTCGGCGAAGTGCCTGGGAGAGGGAGTGCGCTAGGAGG AGGTCCTGCGGCCCAAGCCTGGGTGTAGAGACCGCCCCGGCTAAGGTCAAGCCTCGGGGA CCTGGGCGACCCCGCCGCCCTCCGAGCCGTCGGGAGCCGGTGCAAATCGCCGCTGAGGGC CCTTCCAGCTCCAAGGCTGCGGCTTCCAGGCCTTCCCCACCCCCAGGCCCGCCGGGGCCT CCCCGAAGTCAAACAGCCACAGCGGCGGCAGATAAGCCAGGGGCTGTTGACAGAGGCTGC CTGAGTCCGTGTGGAAGGGCCCAGGGCGGACTTTGCCTCGCCGCAGGTCCCAGAGCCGCA CAGCGCGCCGGCCCAGGCCAATTTAGGGCTTCCCCAGGCAGGAAGCAAGGCTGGTCCGGC TGACCGTGAAGGATGCACGTGGGCCGGACTCTAGGACTCCCGGCTTACCAGCCCCTTACG CGCGGCCCAGGCAGGCCGGAGCCCAGGAAGTTTCTGCCTGCCTGCCTGCCTACCTCTCTG CCTGGGGCATACGTAGTCCCCTTCACCTCCTAGGAGCCCTCTCCAGCCTGCCCAGAGCAG GGAAATTGAAACTGGGCAGCCTCACTCCGGCAGAGGAAAAAGTCACAGGCAGGCTTTTCC TAACCAGCCAGGGGAGAAGTTGGAGGCCCACCCGCAAGGTCAGCTGCATGACTCTATGGC CTTGCCTGCCTCCTCAAACAATTGTGGGGTATTGCTGGAGGAAAAGAGAGGGTGTTTGGC TCCTGTTCATCTGGTTTTCTTCTTTCTGTGCTCCAGGATAGGTAAGGAGACCTGGATGCC ATCCCCTCCTGGACTCAGAATTCCCACACATCGCTTTCCACTAATTATAGAGCAGAATTT AGGTTAACAGACTTCCTTTTTAAACAGCTAATGCCCATGGGAAGGTGAAGTCGTGGGTCA CTTATACCTTAGTGCAAATCGTTTTATAAATTTAAACTGATTGCTCTTCCCACCACCACG ACCACAGGGAGTGCTAGTTTGATAGGGCAATTGGAACATGGGGAGGGTATTGGGCTGGTA GAGAGCTTCAACCAGAGCCTGGATGACTGGAGGCAGGGAGCAAGGGTGAGTGCCAAAGAC AGAGCACTCACCCACCTGCTGGTCTGCTCCAGCAGAAGATACACTGTGTATCTGGCATGA GCAGGTGTCTTCAAGGCTTCCGAATGGAGCTTAGACAAAGGAGGGTCTGAGGCTAGTATC CAGCCAAGCCCTGCCCAGAGAGAGGTACTCCCTGTTCAGCCCTAGGAGTGAGGAATTATC AGAGGGCCCTCCTGTGACTTCATTAAAGTCTCTCACACAGTCAGCAATCCTAGCCTTTGC CTCAAGATACCCAGGTAGCCTCTGGCTGTGTGTTAGTCTCCCAGAGAGGGCACCTTCATG GAGGGAGGCCCGAGCCAGAGGATGTTCAAGCTTCTCCCGGGTTCAAGCGATTCTCCTGCC TCAGCCTCCCGAGTAGCTGGGATTACAGGCACCTACCACCACACCGGCTAAGTTTTGTAT TTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGCTGCTCTCGAACTCCTGACCTCAA GTGATGCATCTGCCTTGGCCTCCCAAAGTGCTGAGATTACAGGTGTCAGCCACCGCGCCT GGGCTTACATTCATTTTTAAAAGCGTGATGTTCTCTGGGGGAGGTATCTCCCTAAGGTGG AAGGTGGCAGTGATTTGAGTTCCATGACACTTGCACAACTCCTGCCATGCTTGGCCATAC CCATTACTGGCAGGGGGGCTAAATCCTGTCATAGCAACCTCAGGTGGTAGGACGGAGGAC TCAGATGAGATAATAGGTATGAAAATCTTTTGTAGGCTGGGAGCAGTGGCTCACACTTGT AATCCCAGCACTTTGGGAGTCCAAGGCGGGAGGATCACTTGAACCCCGGAGTTCGAGGCC AGCCTGGGCAACATAGCAAAATCCTGTCTCTACTAAAAATACAAAAAAAATGTCACGGTG GCTCACACTTGCAATCCCAGCACTTTAGGAGGCCATGGCAGGTAGATCACTTGAGGCCAG GAGTTTGAGACCAGCCTGGCCAACATGATGAAACCCCGTCTCTACTAAAAATATAAAAAT TAGCCAGGCGTTGGTGGTGCACGCCTATAATCCCAGCTACTCAGGAGACTGAGGCAGGAG AATCGCTCAAACCTGGAAGACAGAGGTAGCAGTGAGCCGAGATCGCACCACTCAAATAAA TATGTACATACATACATACAAAAATACAAAAAATCAACCAGGCATGGTGACTCACATCTG TAGTCCCAGCTACTCTGGAGGCTGAGGTGGGAGGATCACCTGAACCCTGGAAGTCCAGGA TGCAGTTAGCTGTGATCGCACCACTGGACTCCAGCCTGGACAATGGGAGTGAGACCTTGT CTCAAAAAAAAAAAAAAAAAAAAAGTATTTTGTAACCTGCTAGCTAGGACTGGCCTTAGT TGCTGCTGCTCTTGATTCTTATGAGATGCAGAAAACCAAGGTCAAGAGAGTAGGTGATGA CACCATTTTACCCCTGCTTGGGAGCAGGTCCATCAATCAAATGGTAGTAGCCCAGGTTTT TAGACACACATCAAATCCTCTTCTGCCAGGCCCACCTGCCAGCCCTCCTCACTGTTTCTG CACAGTTCTAAAAGGATGGTTCAGTTCCCTCACCCTGCCTAACCCAAGGCAAGTTTCCTC TTCACTAAGTCCATTCTGGTCCCACTATCCCCTAAATTCTTCTAGCAGGTCCCTACAGCC ATTAAACTCATTCTTTTGGATAAAGGCAAAGGTGGCCATCCAGTAGAGAAGGGCCCCCAG GCAGGTCTCAGTGTTCCCCAGAAGTCAAAACTCAGACTGCCTTATTGCTGCACATCACTT CACCACGCACAAAGCACTTTCTCAGGCCACATCCCATTTAACCCCCAAAGGGAGGCAGGA TGGTAGCATCCTGCTGGGGATACTTTGGAACCTGCTGGGGCAGTTGGAACTTGGGGAGGG AGGATGGGCTGATAGCTTCAGCCAGAGATTGGGAGGCTGGAGGCAGGGCATGAGGGGATG TAACTCCCCTTGATTTCCTTCTGTAAAATGGGAATGATACCACTTCACGCACTTGCTATG CATGTGCATTCATTATGGCTCTCAAACTGAGTGTGGGAGAAGGGGGTACAGGATGGTGCT GCTGAATATACATGGCACATACATCATCTTCCTGGAATTTTACTTGAGGGTTTGGAGGTG GTGAGTTTTATAATAAAACTTGGATTTATTATGCAGCAGAATGCAAACCTGGTGTGTATT TAAAGATTTTAAAAGGAGTTTTGAAAGTGATGTCATGCTTCTAGTGGGCTGCTTCTGGCT ACACCCCCAGATCCCTGGGGATTGGGCACGTGATCACACCCTAGTGTGCCATGTAAGGGC TTCAGTAGGAAAGTGGGAGCAATGCTGCCTGATGGAAGATGAGAAAGTGCCTGACATGCA ATAGGCAGGTAGCATTTGATGGTTCGTGTTACGGCAGCAGCTATGTCCTCCCAGGGGAAA CAGGCCCACACAGATGGCAGTACTTGGTTGGGTTCACTCAGCTGGAAGGTGACACAGCCA TGACTGGAACCAACTACTGACTTCCCACCCAGTGCTCTACCATAACTTCCATCTCCTCCC CATGGGAAAGGGCTTTATGGTCAGCAGCCCTCTTCTACTTAGGCCACCTCCTCAGTTCTC TCTCTCCCTCTTAGAACTCCCTCTTGTCAGGGAGGTGTATTCCTCTGGGGGTACAACATG TGTAACTGTGCTAAAAGGCAAGTGCCTCTGTGGGGAGGCGGCAGACACAGTTGACATGAG CCAACCTGTGTACTTCAGAGAGGACACAGGGCTGCCGAGTTGCGGGTGGTAAGAGGAGAG GTCCAGAGGATGGGATGCTCTCAAGATTAGCTGGAGGCTAGAAGAGATAAGGGGCACACC AAAAAAACAAAAACAAAAAACAAAAAACAAAAAACAACCCTCGTCTCCTTCCCAGGTTTG TCTAAGTTGACAGGCCCTCAGGTTTGCACCTTATTTTCTTTCTTTTTCTTTTTTTTGAGA CGGAGTCTCACTCTGCTGCCAGGCTAGAGTGCAGTGGCTCGATCACAGCTCACTGCAACC TCCACCTCCCAGATTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACCACAG GCGCATGCCACCATGTCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATG TTGGCTAGGATGGTCTTGATCTCTTGACCTTGTGATCCGCCCACCTCAGTCTCCCAAAGT GCTGGGATTACAGGCATGAGCCACCTCGCCCAGCCCGGCATCTTATTTTCATGGCTTAAG ATTTCTAGGTCCAGATAAAAACCAAGGGTGCCCTGGGCCTTGCCAGCTAATGAGTGCATA GAATCCAGGGATAGCAAGAGAGGCTTGGAGAGCCTTTTCTTTCTCCAGCCCTGTTCTTTC TCCAGGCCCTGCCAGGCTGGCCTTCCTGCCCTGGGCCTGTGTACAGGTTTGTTTCTGTGT ATGTCTGTCTCCCTAAATGAGAGGAACCAAGGTCCTGAGTGAAGGAATCAGTGATTGAGA TTTGTTCAGCTTCTGCCTCATACCATGGAATGGGATGGGGGAGCTGGGCGCCTATCATGC TTAAGCCTTATGTACTACTCACAGCAACCCAGTAAGGATAGTTATTTCCTCATTTTATAG ATCTTTTTCTTACAGATGCACAGAGGCTTGTTTCTTGGGCCCTGGAATCTTTTGAGGCAT TGGTAGTAATAAAAATTTGGGGGGCCGGGCCTGGTGGCTCACACCTGTAATCCCAGCAGT TTGGGAGGCTGAGGTGGGTGGAACACCTGAGATCAGGAGTTGGAGACCAGCCTGACCAAT ATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATAGTGGTGTGCAC CTGTAGTCTCAGCTACTCGGGAGGCTGAAACAAGAGAACCGCCTGAACCCGGGAGGTAGA GGTTGCAGTGAGGCCAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCC ATCTGAAAAAAAAAAAAAAAAAAAAAAAAAATGGCCCTACTCTAGACCAACTTAGAACAT CCCTGCGGTAGGCCTGATAATCTGCAATTTTTAACAAGGGTGACCATCAGGTAATTCCGA TGTTCACAACAGTTCAAAAACCTCGACAGAGCATTTTCGTAACCTGCCCACGCGTTCTTC AGTGGCAGAGCTGGAGCGCAAACCGGGGGCTTCAGATGCTAAGTCCAGGCTCTTGACAGC TCACTGGAGACGCTGGAATCACCTTCACTGCGCCTGTATCAGCACCCGCCACACAGGCGC ACAAATAAACCTTCCCAGAGTGAATGAATGAATTAATGACTCATCCAGCCCCAGCTGCTT CCGGTGGGTCGGGGGCGTGGCGAGACCCTGTTTCAGTGGAGGGAGGGCTTATGCATTGCC GAGACGCCGATTATCAGACCTTGACCCTGTCGCTTTCAGAAAAACCACTGGCAGAAGATC CGGACCATGGTCAATCTGCCGGTCATAAGCCCTTTCAAGAAGCGCTACGCCTGGGTGCAG CTGGCAGGGCACACTGGTGAGCAGTGGGGCGGGTGGGCGGGTGCCCGCGACGGGAAGGGG CTGGGCGGCGCTGACGGATGCCGGTCCTCAGGGAGTTTTAAGGCGGCGGGCACCAGCGGG CTGATCCTGAAGCGCTGCTCGGAGCCGGAGCGCTACTGCCTGGCGCGGCTGATGGCTGAC GCGCTGCGCGGCTGCGTGCCTGCCTTCCACGGCGTGGTGGAGCGCGACGGCGAAAGCTAC CTGCAGCTGCAGGACCTGCTCGATGGCTTCGACGGACCTTGTGTGCTCGACTGCAAAATG GGCGTCAGGTATGCGTGCCCTGCCAGGTCGGTTGGGGGGATCAAGTAGGGGTCCGGGGCC GGGACAGCTGCTTGAGGGGGACCCGGGGCGAGTGCTCGAAGGGGTCTCCGTGTGCGCCCC CTCATGCCCTGGCCGCTGCCTGCGCCCCCACAGGACTTACCTAGAGGAGGAGCTGACCAA GGCCCGTGAGCGGCCCAAGCTGCGGAAGGACATGTACAAGAAAATGCTGGCGGTGGATCC TGAAGCTCCCACGGAGGAGGAGCACGCGCAGCGCGCCGTCACCAAGCCGCGCTACATGCA GTGGCGGGAAGGCATCAGCTCCAGCACCACCCTCGGCTTCCGCATCGAGGGCATCAAGGT GAGGCAGGCGCGCTTCGCTGGCACCGCCGCAGCCCCACTGCGCGCTGTCTTTCCCGATCC CCCGCTCCCGCCCCGCCTGCCCCTCCGCCCTCTCCCACCGCCTCGCCGTCCCCTGCAACT GGGAGGTACCGCTGCTCTACGCTGTCCTCTTCCCCACTGGCGGGCCCGGGGCCCCTGACA CTCCTGTCCCACATCCAGAAAGCGGACGGCTCCTGCAGCACCGACTTCAAGACTACGCGA AGCCGAGAGCAGGTGCTTCGCGTCTTTGAAGAGTTTGTGCAAGGAGATGAGGAAGTGCTG GTGAGAGCGGGATCCCAAACCCTGAGGTGTTGGGGAGCCTGAAGCCGAGGACTGCCCCTG TCATCTGGCCCAGTGCCCTCGGCTGTGTCCCCACCATGGCCCTCACCGCGCTGGCTCGCA ACTGCTCTACGCTCCTTCCCTTCTGGGCCACGCTGGGCGGGGCCCTGGGTCCTCCTCCTG GCGGCATTTGCCAAGCACAGCGTGGGTCCCGGCTCCTCATCGTTAGCAGGGGCTCATTTG GCGTTTAGTTAATTTGCCCTCCTCTCCCACCCCACCCTCTGCAGAGGCGGTATCTGAACC GCCTGCAGCAGATCCGGGACACCCTGGAGGTATCCGAGTTCTTCAGGAGGCACGAGGTAA GCGGCGGCTGCCCGGGTGCCCGGGCCGCGAGGGCTAGGGCGGGAACCCGGCAAGGGCGTC TCTGGGCAGGGCCGCGGCCTGACGGTGCGGGGCTCGCAGGTGATCGGCAGCTCGCTCCTC TTTGTGCACGATCACTGCCATCGCGCCGGCGTGTGGCTCATCGACTTCGGCAAGACCACG CCCCTCCCCGATGGCCAGATCCTGGACCACCGGCGGCCCTGGGAGGAGGGCAACCGCGAG GACGGCTATTTGCTGGGGCTGGACAATCTCATTGGCATCCTGGCCAGCCTGGCTGAGAGA TGAGGCTGGACTCCTGTCCCCGCGGGCCGCTCACCTGACATGTGGACCTGCAGCTTTGTC CCCACTGTGCATGCCGGCTTGAGACTGGAGCCCCGCGGTGCAGGGCAGTTCACCGGGTCC TGCAGGACCAGGTGCCAGCCACTAAGGGGGGGCACCGCCGATGCCAGGGGTTTTGCCCAC CCGGGCCCCAGCGTTCCCAGAGCCAAATGACACTAACTTATAGAAGGGGAGGGGGCAAAG GGCTTCTTCCTCAGGCCAGCTCTTCTGAGGAGGCTCTGCCCTCTCCAGAGGTGCCAGACC GCGGATTTTATTTAGCAAGCCCAGACCTTCCGGTCTAACGTCTCACACCACGACGGACTC CCCTTCCTAATAAAACTCAAAGACAA OMIM ID 147521