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Gene information for ITGA5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3678
Official gene symbolITGA5
Full nameintegrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Aliases,CD49e,FNRA,VLA5A,
Gene summaryThe product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q11-q13
Gene position54813050 - 54789045  Map Viewer
Gene orientationminus
Gene size24006 bp
Gene sequence
OMIM ID135620