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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for INHBA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3624
Official gene symbolINHBA
Full nameinhibin, beta A
Aliases,EDF,FRP,
Gene summaryThe inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p15-p13
Gene position41742706 - 41728601  Map Viewer
Gene orientationminus
Gene size14106 bp
Gene sequence
OMIM ID147290