| Entrez gene ID | | 3623 |
|
| Official gene symbol | | INHA |
|
| Full name | | inhibin, alpha |
|
| Aliases | | ,-, |
|
| Gene summary | | The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. [provided by RefSeq] |
|
| Location | | Chromosome: 2 Locus: 2q33-q36 |
|
| Gene position | | 220436954 - 220440427 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 3474 bp |
|
| Gene sequence |
| |
|
|
