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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3574
Official gene symbolIL7
Full nameinterleukin 7
Aliases,IL-7,
Gene summaryThe protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q12-q13
Gene position79717758 - 79645005  Map Viewer
Gene orientationminus
Gene size72754 bp
Gene sequence
OMIM ID146660