| Entrez gene ID | | 3574 |
| Official gene symbol | | IL7 |
| Full name | | interleukin 7 |
| Aliases | | ,IL-7, |
| Gene summary | | The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq] |
| Location | | Chromosome: 8 Locus: 8q12-q13 |
| Gene position | | 79717758 - 79645005 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 72754 bp |
| Gene sequence |
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| OMIM ID | | 146660 |
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