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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3558 Official gene symbol IL2 Full name interleukin 2 Aliases ,IL-2,TCGF,lymphokine, Gene summary The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq] Location Chromosome: 4   Locus: 4q26-q27 Gene position 123377650 - 123372625  Map Viewer Gene orientation minus Gene size 5026 bp Gene sequence >IL2:complement(47920346..47925371):Length=5026 AGTTCCCTATCACTCTCTTTAATCACTACTCACAGTAACCTCAACTCCTGCCACAATGTA CAGGATGCAACTCCTGTCTTGCATTGCACTAAGTCTTGCACTTGTCACAAACAGTGCACC TACTTCAAGTTCTACAAAGAAAACACAGCTACAACTGGAGCATTTACTGCTGGATTTACA GATGATTTTGAATGGAATTAATGTAAGTATATTTCCTTTCTTACTAAAATTATTACATTT AGTAATCTAGCTGGAGATCATTTCTTAATAACAATGCATTATACTTTCTTAGAATTACAA GAATCCCAAACTCACCAGGATGCTCACATTTAAGTTTTACATGCCCAAGAAGGTAAGTAC AATATTTTATGTTCAATTTCTGTTTTAATAAAATTCAAAGTAATATGAAAATTTGCACAG ATGGGACTAATAGCAGCTCATCTGAGGTAAAGAGTAACTTTAATTTGTTTTTTTGAAAAC CCAAGTTTGATAATGAAGCCTCTATTAAAACAGTTTTACCTATATTTTTAATATATATTT GTGTGTTGGTGGGGGTGGGAAGAAAACATAAAAATAATATTCTCACTTTATCGATAAGAC AATTCTAAACAAAAATGTTCATTTATGGTTTCATTTAAAAATGTAAAACTCTAAAATATT TGATTATGTCATTTTAGTATGTAAAATACCAAAATCTATTTCCAAGGAGCCCACTTTTAA AAATCTTTTCTTGTTTTAGGAAAGGTTTCTAAGTGAGAGGCAGCATAACACTAATAGCAC AGAGTCTGGGGCCAGATATCTGAAGTGAAATCTCAGCTCTGCCATGTCCTAGCTTTCATG ATCTTTGGCAAATTACCTACTCTGTTTGTGATTCAGTTTCATGTCTACTTAAATGAATAA CTGTATATACTTAATATGGCTTTGTGAGAATTAGTAAGTAAATGTAAAGCACTCAGAACC GTGTCTGGCATAAGGTAAATACCATACAAGCATTAGCTATTATTAGTAGTATTAAAGATA AAATTTTCACTGAGAAATACAAAGTAAAATTTTGGACTTTATCTTTTTACCAATAGAACT TGAGATTTATAATGCTATATGACTTATTTTCCAAGATTAAAAGCTTCATTAGGTTGTTTT TGGATTCAGATAGAGCATAAGCATAATCATCCAAGCTCCTAGGCTACATTAGGTGTGTAA AGCTACCTAGTAGCTGTGCCAGTTAAGAGAGAATGAACAAAATCTGGTGCCAGAAAGAGC TTGTGCCAGGGTGAATCCAAGCCCAGAAAATAATAGGATTTAAGGGGACACAGATGCAAT CCCATTGACTCAAATTCTATTAATTCAAGAGAAATCTGCTTCTAACTACCCTTCTGAAAG ATGTAAAGGAGACAGCTTACAGATGTTACTCTAGTTTAATCAGAGCCACATAATGCAACT CCAGCAACATAAAGATACTAGATGCTGTTTTCTGAAGAAAATTTCTCCACATTGTTCATG CCAAAAACTTAAACCCGAATTTGTAGAATTTGTAGTGGTGAATTGAAAGCGCAATAGATG GACATATCAGGGGATTGGTATTGTCTTGACCTACCTTTCCCACTAAAGAGTGTTAGAAAG ATGAGATTATGTGCATAATTTAGGGGGTGGTAGAATTCATGGAAATCTAAGTTTGAAACC AAAAGTAATGATAAACTCTATTCATTTGTTCATTTAACCCTCATTGCACATTTACAAAAG ATTTTAGAAACTAATAAAAATATTTGATTCCAAGGATGCTATGTTAATGCTATAATGAGA AAGAAATGAAATCTAATTCTGGCTCTACCTACTTATGTGGTCAAATTCTGAGATTTAGTG TGCTTATTTATAAAGTGGAGATGATACTTCACTGCCTACTTCAAAAGATGACTGTGAGAA GTAAATGGGCCTATTTTGGAGAAAATTCTTTTAAATTGTAATATACCATAGAAATATGAA ATATTATATATAATATAGAATCAAGAGGCCTGTCCAAAAGTCCTCCCAAAGTATTATAAT TTTTTATTTCACTGGGACAAACATTTTTAAAATGCATCTTAATGTAGTGATTGTAGAAAA GTAAAAATTTAAGACATATTTAAAAATGTGTCTTGCTCAAGGCTATATTGAGAGCCACTA CTACATGATTATTGTTACCTAGTGTAAAATGTTGGGATTGTGATAGATGGCATCCAAGAG TTCCTTCTCTCTCAACATTCTGTGATTCTTAACTCTTAGACTATCAAATATTATAATCAT AGAATGTGATTTTTATGCTTCCACATTCTAACTCATCTGGTTCTAATGATTTTCTATGCA GATTGGAAAAGTAATCAGCCTACATCTGTAATAGGCATTTAGATGCAGAAAGTCTAACAT TTTGCAAAGCCAAATTAAGCTAAAACCAGTGAGTCAACTATCACTTAACGCTAGTCATAG GTACTTGAGCCCTAGTTTTTCCAGTTTTATAATGTAAACTCTACTGGTCCATCTTTACAG TGACATTGAGAACAGAGAGAATGGTAAAAACTACATACTGCTACTCCAAATAAAATAAAT TGGAAATTAATTTCTGATTCTGACCTCTATGTAAACTGAGCTGATGATAATTATTATTCT AGGCCACAGAACTGAAACATCTTCAGTGTCTAGAAGAAGAACTCAAACCTCTGGAGGAAG TGCTAAATTTAGCTCAAAGCAAAAACTTTCACTTAAGACCCAGGGACTTAATCAGCAATA TCAACGTAATAGTTCTGGAACTAAAGGTAAGGCATTACTTTATTTGCTCTCCTGGAAATA AAAAAAAAAAAGTAGGGGGAAAAGTACCACATTTTAAAGTGACATAACATTTTTGGTATT TGTAAAGTACCCATGCATGTAATTAGCCTACATTTTAAGTACACTGTGAACATGAATCAT TTCTAATGTTAAATGATTAACTGGGGAGTATAAGCTACTGAGTTTGCACCTACCATCTAC TAATGGACAAGCCTCATCCCAAACTCCATCACCTTTCATATTAACACAAAACTGGGAGTG AGAGAAGGTACTGAGTTGAGTTTCACAGAAAGCAGGCAGATTTTACTATATATTTTTCAA TTCCTTCAGATCATTTACTGGAATAGCCAATACTGATTACCTGAAAGGCTTTTCAAATGG TGTTTCCTTATCATTTGATGGAAGGACTACCCATAAGAGATTTGTCTTAAAAAAAAAAAC TGGAGCCATTAAAATGGCCAGTGGACTAAACAAACAACAATCTTTTTAGAGGCAATCCCC ACTTTCAGAATCTTAAGTATTTTTAAATGCACAGGAAGCATAAAATATGCAAGGGACTCA GGTGATGTAAAAGAGATTCACTTTTGTCTTTTTATATCCCGTCTCCTAAGGTATAAAATT CATGAGTTAATAGGTATCCTAAATAAGCAGCATAAGTATAGTAGTAAAAGACATTCCTAA AAGTAACTCCAGTTGTGTCCAAATGAATCACTTATTAGTGGACTGTTTCAGTTGAATTAA AAAAATACATTGAGATCAATGTCATCTAGACATTGACAGATTCAGTTCCTTATCTATGGC AAGAGTTTTACTCTAAAATAATTAACATCAGAAAACTCATTCTTAACTCTTGATACAAAT TTAAGACAAAACCATGCAAAAATCTGAAAACTGTGTTTCAAAAGCCAAACACTTTTTAAA ATAAAAAAATCCCAAGATATGACAATATTTAAACAATTATGCTTAAGAGGATACAGAACA CTGCAACAGTTTTTTAAAAGAGAATACTTATTTAAAGGGAACACTCTATCTCACCTGCTT TTGTTCCCAGGGTAGGAATCACTTCAAATTTGAAAAGCTCTCTTTTAAATCTCACTATAT ATCAAAATATTTCCTCCTTAGCTTATCAACTAGAGGAAGCGTTTAAATAGCTCCTTTCAG CAGAGAAGCCTAATTTCTAAAAAGCCAGTCCACAGAACAAAATTTCTAATGTTTAAACTT TTAAAAGTTGGCAAATTCACCTGCATTGATACTATGATGGGGTAGGGATAGGTGTAAGTA TTTATGAAGATGTTCTTCACACAAATTTATCCCAAACAGAAGCATGTCCTAGCTTACTCT AGTGTAGTTCTGTTCTGCTTTGGGGAAAATATAAGGAGATTCACTTAAGTAGAAAAATAG GAGACTCTAATCAAGATTTAGAAAAGAAGAAAGTATAATGTGCATATCAATTCATACATT TAACTTACACAAATATAGGTGTACATTCAGAGGAAAAGCGATCAAGTTTATTTCACATCC AGCATTTAATATTTGTCTAGATCTATTTTTATTTAAATCTTTATTTGCACCCAATTTAGG GAAAAAATTTTTGTGTTCATTGACTGAATTAACAAATGAGGAAAATCTCAGCTTCTGTGT TACTATCATTTGGTATCATAACAAAATATGTAATTTTGGCATTCATTTTGATCATTTCAA GAAAATGTGAATAATTAATATGTTTGGTAAGCTTGAAAATAAAGGCAACAGGCCTATAAG ACTTCAATTGGGAATAACTGTATATAAGGTAAACTACTCTGTACTTTAAAAAATTAACAT TTTTCTTTTATAGGGATCTGAAACAACATTCATGTGTGAATATGCTGATGAGACAGCAAC CATTGTAGAATTTCTGAACAGATGGATTACCTTTTGTCAAAGCATCATCTCAACACTGAC TTGATAATTAAGTGCTTCCCACTTAAAACATATCAGGCCTTCTATTTATTTAAATATTTA AATTTTATATTTATTGTTGAATGTATGGTTTGCTACCTATTGTAACTATTATTCTTAATC TTAAAACTATAAATATGGATCTTTTATGATTCTTTTTGTAAGCCCTAGGGGCTCTAAAAT GGTTTCACTTATTTATCCCAAAATATTTATTATTATGTTGAATGTTAAATATAGTATCTA TGTAGATTGGTTAGTAAAACTATTTAATAAATTTGATAAATATAAA OMIM ID 147680