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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL1RN (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3557
Official gene symbolIL1RN
Full nameinterleukin 1 receptor antagonist
Aliases,DIRA,ICIL-1RA,IL-1ra3,IL1F3,IL1RA,IRAP,MGC10430,MVCD4,
Gene summaryThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q14.2
Gene position113875470 - 113891593  Map Viewer
Gene orientationplus
Gene size16124 bp
Gene sequence
OMIM ID147679