| Entrez gene ID | | 3557 |
| Official gene symbol | | IL1RN |
| Full name | | interleukin 1 receptor antagonist |
| Aliases | | ,DIRA,ICIL-1RA,IL-1ra3,IL1F3,IL1RA,IRAP,MGC10430,MVCD4, |
| Gene summary | | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq] |
| Location | | Chromosome: 2 Locus: 2q14.2 |
| Gene position | | 113875470 - 113891593 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 16124 bp |
| Gene sequence |
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| OMIM ID | | 147679 |
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