| Entrez gene ID | | 346389 |
| Official gene symbol | | MACC1 |
| Full name | | metastasis associated in colon cancer 1 |
| Aliases | | ,7A5,SH3BP4L, |
| Gene summary | | MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM] |
| Location | | Chromosome: 7 Locus: 7p21.1 |
| Gene position | | 20257013 - 20174278 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 82736 bp |
| Gene sequence |
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| OMIM ID | | 612646 |
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