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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MACC1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID346389
Official gene symbolMACC1
Full namemetastasis associated in colon cancer 1
Aliases,7A5,SH3BP4L,
Gene summaryMACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]
LocationChromosome: 7   Locus: 7p21.1
Gene position20257013 - 20174278  Map Viewer
Gene orientationminus
Gene size82736 bp
Gene sequence
OMIM ID612646