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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ID4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3400 Official gene symbol ID4 Full name inhibitor of DNA binding 4, dominant negative helix-loop-helix protein Aliases ,IDB4,bHLHb27, Gene summary Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 [PubMed 7665172]).[supplied by OMIM] Location Chromosome: 6   Locus: 6p22-p21 Gene position 19837617 - 19840915  Map Viewer Gene orientation plus Gene size 3299 bp Gene sequence >ID4:19777617..19780915:Length=3299 AGGCGCGGTTGTGAGTAGTACCGGGAGTGGGGTGATCCCGGGCTAGGGGAGCGCGGCGGC CGCGATCGGGCTTAGTCGGAGCTCCGAAGGGAGTGACTAGGACACCCGGGTGGGCTACTT TTCTTCCGGTGCTTTTGCTTTTTTTTTCCTTTGGGCTCGGGCTGAGTGTCGCCCACTGAG CAAAGATTCCCTCGTAAAACCCAGAGCGACCCTCCCGTCAATTGTTGGGCTCGGGAGTGT CGCGGTGCCCCGAGCGCGCCGGGCGCGGAGGCAAAGGGAGCGGAGCCGGCCGCGGACGGG GCCCGGAGCTTGCCTGCCTCCCTCGCTCGCCCCAGCGGGTTCGCTCGCGTAGAGCGCAGG GCGCGCGCGATGAAGGCGGTGAGCCCGGTGCGCCCCTCGGGCCGCAAGGCGCCGTCGGGC TGCGGCGGCGGGGAGCTGGCGCTGCGCTGCCTGGCCGAGCACGGCCACAGCCTGGGTGGC TCCGCAGCCGCGGCGGCGGCGGCGGCGGCAGCGCGCTGTAAGGCGGCCGAGGCGGCGGCC GACGAGCCGGCGCTGTGCCTGCAGTGCGATATGAACGACTGCTATAGCCGCCTGCGGAGG CTGGTGCCCACCATCCCGCCCAACAAGAAAGTCAGCAAAGTGGAGATCCTGCAGCACGTT ATCGACTACATCCTGGACCTGCAGCTGGCGCTGGAGACGCACCCGGCCCTGCTGAGGCAG CCACCACCGCCCGCGCCGCCACACCACCCGGCCGGGACCTGTCCAGCCGCGCCGCCGCGG ACCCCGCTCACTGCGCTCAACACCGACCCGGTGAGAGGCCGGGCGCCGGCCGTGGGCGGA CGCCGCGGGGGATGGGAGGTTGGTGGCGTGGTGGCGGGACGCGGGCGCTCACCGTCCTCC GGGCAGGGGCGGGCCAGGAATGACAGCCCCCTCCCCCTGCTCCTCCGGGCTCCCCCGGGC CGCCAGCAGCCGGCCGGGCTCGGCGAGCGCGGGTCCGGGAGAACGCGCAGGGCGGGACTC GGGGCTGTGGGCGCCCTGGGCTGTCAAGTCCCGCCTGAGCCCGGAGGGGCCCCCCCGGCT ACAGGCTGGGGTGGGGGCGTCGGCGCGCCAGCCTGATTTCCGAGGACAATCCAGGACCGT GTCGAGCGCGTTGTTTGCGCCTGCTAACCTTTCCCTTGGTGTTCGGTTGCTGTTCCAGGC CGGCGCGGTGAACAAGCAGGGCGACAGCATTCTGTGCCGCTGAGCCGCGCTGTCCAGGTG AGCGCGCATTTCCCGTCTCGGGTGGCCGGTCACCAGAGACGCCCGTCCCCGAGGGCTTCC GGGGCCAGGCACCGCGGTGTTCTTTGCCCCCAGCGTTTCTGAGAGCAAACTCCCAAGGAA GTAAATCCCCTCTCTCCCTGCCACCTAAGTAGCAAGTAAACCCGTACTTAGCCTTAGAAC TCGAGGTTCAGTCTCGGTGGAGACGGGTCAGCCCTTGTCCCCGCCGTCCCCGTGTTTTTT CTGGTGGTCAGCGGGCTCTTCTGCCTTCCCTAGTTCCCGAGGGAGGGCACCCTCGTGGGC ATGGGAGCTGCCCCGGTGTCCTCCCGTGCAGTCTGTCACCCACAAAGGGGGACGCGGGCA GGGCGCCGGAGTGGGTCCCCTCTCCGGGCTTCCCGAGGGCCGCAGCTGCCTGCTCGGCGC CTGGCCCGGCCGCGGGCGGGTGTTGTCTGACCTGGTGGTTTGTTTTGGGTTGTTGATCAA GCATGTCTTGAGTTTGGTCGGTGGCGCCAGTTAGTCTGCAGCGAGAAGGTTCACACACCC CCTCTATTCATTCCTCTTCCACAGGTGTGCGGCCGCCTGAGCCCGAGCCAGGAGCACTAG AGAGGGAGGGGGAAGAGCAGAAGTTAGAGAAAAAAAGCCACCGGAGGAAAGGAAAAAACA TCGGCCAACCTAGAAACGTTTTCATTCGTCATTCCAAGAGAGAGAGAGGAAAGAAAAATA CAACTTTCATTCTTTCTTTGCACGTTCATAAACATTCTACATACGTATTCTCTTTTGTCT CTTCATTTATAACTGCTGTGAATTGTACATTTCTGTGTTTTTTGGAGGTGCAGTTAAACT TTTAAGCTTAAGTGTGACAGGACTGATAAATAGAAGATCAAGAGTAGATCCGACTTTAGA AGCCTACTTTGTGACCAAGGAGCTCAATTTTTGTTTTGAAGCTTTACTAATCTACCAGAG CATTGTAGATATTTTTTTTTTACATCTATTGTTTAAAATAGATGATTATAACGGGGCAGA GAACTTTCTTTTCTCTGCAAGAATGTTACATATTGTATAGATAAATGAGTGACATTTCAT ACCATGTATATATAGAGATGTTCTATAAGTGTGAGAAAGTATATGCTTTAATAGATACTG TAATTATAAGATATTTTTAATTAAATATTTTTTTGTAAATATTATGTGTGTGTTTTTTTT TAATCTATGGGAATATTTCTTTTGGAAAATCATTTTTCAGCTCAATTACAGAGCTCTTGA TATCTTGAATGTCTTTTCTGTTTGGCCTGGCTCTTAATTTGCTTTTGTTTTGCCCAGTAT AGACTCGGAAGTAACAGTTATAGCTAGTGGTCTTGCATGATTGCATGAGATGTTTAATCA CAAATTAAACTTGTTCTGAGTCCATTCAAATGTGTTTTTTTAAATGTAGATTGAAATCTT TGTATTTGAAGCATACATGTTGAAAATACACCTTATCAGTTTTTAAGTACAGGGTTTTAT AGTGTAATATATACAGAGTAAGTGTTTGTTTTTGTTTTTCAACTGAGGTCAAAATGGATT CTGAATGATTTTGCATATGGGATGAGGAAATGCTTGGATCCTTAAGGAGTTTACGAAATC TGCTGTTTTATCAAAGTGAAAAAAAATTGCTTATTACTCTTCATTTTACACTAAAGCTTA ATGTCACTAAGTTTCATGTCTGTACAGATTATTTAAATCATGGAAATGAAAAAAATGTTC TCTGCTTGCTACCAAAGGACAAACTCTTGGAAATGAACACTTTCTGCTTTCCTTCCTCCA AAGAATTAATAGGCAACAGTGGGAGAAAAAAAAGGCATAATGGCAAATCCTTCAAGCAGG GATAAAAGTCGATCTTCAAACATTAACTTAAGCAGACCAAAAATTCTGATGACCGCATCT AGATTATTTTTTTATAAAAATGATTTTCACTATAGCTATGTTACGCTAAGCTACTGTCCA ATCTCTTGTGATGTGTAACTTTTACATGTGAATATTAAAGTAGATTTCTCTGTCTTGTA OMIM ID 600581