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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NRG1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3084
Official gene symbolNRG1
Full nameneuregulin 1
Aliases,ARIA,GGF,GGF2,HGL,HRG,HRG1,HRGA,NDF,SMDF,
Gene summaryThe protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq]
LocationChromosome: 8   Locus: 8p12
Gene position31496820 - 32622558  Map Viewer
Gene orientationplus
Gene size1125739 bp
Gene sequence
OMIM ID142445