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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GYPB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2994
Official gene symbolGYPB
Full nameglycophorin B (MNS blood group)
Aliases,CD235b,GPB,GPB.NY,GYPHe.NY,HGpMiVI,MNS,SS,
Gene summaryGlycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q28-q31
Gene position144940496 - 144917257  Map Viewer
Gene orientationminus
Gene size23240 bp
Gene sequence
OMIM ID111740