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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDIA3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2923
Official gene symbolPDIA3
Full nameprotein disulfide isomerase family A, member 3
Aliases,ER60,ERp57,ERp60,ERp61,GRP57,GRP58,HsT17083,P58,PI-PLC,
Gene summaryThis gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q15
Gene position44038590 - 44064804  Map Viewer
Gene orientationplus
Gene size26215 bp
Gene sequence
OMIM ID602046