| Entrez gene ID | | 29127 |
| Official gene symbol | | RACGAP1 |
| Full name | | Rac GTPase activating protein 1 |
| Aliases | | ,HsCYK-4,ID-GAP,MgcRacGAP, |
| Gene summary | | Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM] |
| Location | | Chromosome: 12 Locus: 12q13.12 |
| Gene position | | 50419307 - 50382945 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 36363 bp |
| Gene sequence |
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| OMIM ID | | 604980 |