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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GMDS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2762
Official gene symbolGMDS
Full nameGDP-mannose 4,6-dehydratase
Aliases,GMD,SDR3E1,
Gene summaryGDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM]
LocationChromosome: 6   Locus: 6p25
Gene position2245846 - 1624041  Map Viewer
Gene orientationminus
Gene size621806 bp
Gene sequence
OMIM ID602884