| Entrez gene ID | | 2762 |
| Official gene symbol | | GMDS |
| Full name | | GDP-mannose 4,6-dehydratase |
| Aliases | | ,GMD,SDR3E1, |
| Gene summary | | GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM] |
| Location | | Chromosome: 6 Locus: 6p25 |
| Gene position | | 2245846 - 1624041 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 621806 bp |
| Gene sequence |
| |
| OMIM ID | | 602884 |
|