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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Abcb11 (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID27413
Official gene symbolAbcb11
Full nameATP-binding cassette, sub-family B (MDR/TAP), member 11
AliasesABC16,Bsep,Lith1,PFIC2,PGY4,SPGP
Gene summaryThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt transporter in humans and mice. Mutations in the human gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq]
LocationChromosome: 2   Locus: 2 C2|2 38.4 cM
Gene position69180673 - 69076339  Map Viewer
Gene orientationminus
Gene size104335 bp
Gene sequence