Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GLA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2717 Official gene symbol GLA Full name galactosidase, alpha Aliases ,GALA, Gene summary This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq] Location Chromosome: X   Locus: Xq22 Gene position 100663001 - 100652779  Map Viewer Gene orientation minus Gene size 10223 bp Gene sequence >GLA:complement(23949087..23959309):Length=10223 AAACAATAACGTCATTATTTAATAAGTCATCGGTGATTGGTCCGCCCCTGAGGTTAATCT TAAAAGCCCAGGTTACCCGCGGAAATTTATGCTGTCCGGTCACCGTGACAATGCAGCTGA GGAACCCAGAACTACATCTGGGCTGCGCGCTTGCGCTTCGCTTCCTGGCCCTCGTTTCCT GGGACATCCCTGGGGCTAGAGCACTGGACAATGGATTGGCAAGGACGCCTACCATGGGCT GGCTGCACTGGGAGCGCTTCATGTGCAACCTTGACTGCCAGGAAGAGCCAGATTCCTGCA TCAGGTATCAGATATTGGGTACTCCCTTCCCTTTGCTTTTCCATGTGTTTGGGTGTGTTT GGGGAACTGGAGAGTCTCAACGGGAACAGTTGAGCCCGAGGGAGAGCTCCCCCACCCGAC TCTGCTGCTGCTTTTTTATCCCCAGCAAACTGTCCCGAATCAGGACTAGCCCTAAACTTT CTCTGTGTGACCTTTCCTGGGATGGGAGTCCGGCCAGCGGCCCCTGTTTCTTTCTCTCTC TCTCTCTCTCTCGTTCTCCTTCTCTTTCTCTTTCTCTTCTTTCCTCTCTCTTTCTCTCTC TCCCTGCCCGGTTCTCTTTTTTCACTGCTCCTTGCAGAGCAGGGCCACCCCATAGGCAGT GTGCCCAAAGTAGCCCTGCCCGGTTCTATTCAGACCCTTCTTGTGAACTTCTGCTCTTCC TCTGCCGGGTGCTAACCGTTAGAACATCTAGGGTGGGTAGGAGGAATGGGGAACTAAGAT TCGTGCCATTTTTTCTCCTTTTGGGGTCGTGGATTTCTCGGCAGTATCTCGAGGGAGTTA GAGAGACCATAAGGTCGCTGAGATCTCTCCCACCTCGCCCATGAGCGTGGCATCAGGCTG GAAGGTTGACATGGAGGAACTTTATACATTTACACCTTTGCGTGAGGGTTGAGGCTGGAT TAGATAGGTATTGAACATATCTGACCCTCACAATCCTTATCTGTAAATTGGGATTACAAC CTTTTAATTTCAGGGAGCTGACAAAAAAAATCTGAAAAATAGTTCTTATCTCACACAGGT GAGTTTTCAAGGAGATAACCTATTTAAAGTACATAGCACAGCGCTTGACCATTCAACTGC GCTTACAGAGCAAATGTTCAATGGGAAAATGAATGTAAATCTACAAATCTGAATGAATAT GTGTATTTTTCTGGAGAGAGGATATTTACCTTTCTTCAAATTCTCAAAGGGCTCTGTGAT TTAAAAAAGGTTAGGAATCACTGATAGATGTTGGTAAAAGGTGGCAGTCACAGTACATTT CTGTGTCCATAAGTTATTCCTATGAATATCTTTATAGATAAAGTCAGGATGTTGGTCAGA CATCACAGAAGAAATTGGCCTTGTAAGTTTCATGTGACCCTGTGGTACAGTATGTGTGGC AATTTTGCCCATCACGGATTTTTTTTTATTGGTATTTGCATCTGATTATAAAACTAATGC ATGATCATTGCAAAAAATGTAGATAAAGAAGAGCAAAATGAAAATAAAGATTTCCCCCCA CCGTTCCACCACCCAGAAATAATCATGGTTTAAATGTTAATATACAACCTTACAATTGTT TTCTATATAAATGAAAACATAGATTTCTTTATTTCATTATTTTCCATAAAAAATGGATCA TGTTTATGTCATGTTTGGCTAATGGCAAGACCCTGGCACCCAGTCTGGGCTCAAATTCTG CCTCATTGTTACTTAGCCCTGTGACATTGGGTAAATTACACTTTTTTTTTTTTTTTTTTT TTGAGACGGGGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCAC TGCAAGCTCCGCCTCCTGGGTTCACGCCATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGG ACTACAGGCGCCTGCCACCACGCCTGGCTCTTTTTTTTTTTTTTTTTTTTTTTAGTACAG ACGGGGTTTCACCATGTTAGCCAGGGTGGTCTCAATCTCCTGACCTCGTGATTCGCCCGC CTCAGCCTCCCAAAGTGCTGGTGTGAGCCACCGTGCCCAGCCTTACTTTTTTTTTTGAGA GGGGGTCTCACTCTGTCACCCAGGTTGGAGTGCAGTGGCGCGATCTCTGCTCAGTGCAAA CTCCACCTCCCGGGTTTAAGCAGTTCTCCTGTCGTAGTCTCCTGAGTAGCTGGGATTACA GGCACACCACCACGGCCAGCTAATTTTTGTATTTTCAGTAGAGACGGGTTTCACCATGTT GCCCAAGCTGGTCTCGAACTCCTGGCCTCAAGTGATCTGCCCGCCTTGGCCTCCCAGAGT GCTGGGATTACAGGTGTGAGCCACCGCACCCGGCCTCTTTTTTCTTTTTTAGTCTATCAT ACCTTGCAAATACAGTGGTTCTTCCTATGTGTTGGTTTTGATATTTATGTAATCAAACAC ATCAGTTTTTCCTTTCTGATTTCTGACTTTGGGGTCATGCTGAGAAAGTCCTTTCCTACC TGAAGATAATACAGTATATACGTTTCTTACTAGTATTTTTGTGGATTTTTAAAATATTTA AATCTTTAGTCCATCTGAACTTTGTTCTTCTATCAGAAATGCCACATTTAATAAATAATA AGTCCCATGGTATCAGATGGCTGGAAGGACCTCTTTCGAAACTTTGTTTAATTCCATTAA TCTGTGTATTCTTATTCTAATGCTAATAGTTCCACACTAGCTTCCTTTATCTTTTTTTTC TTTTTTTTTTTTTTTTTGAGCTGGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTACAATGT CACGATCTCGGTTCACCGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCATC CTCGCGAGTAGCTGGAATTACAGGCATGCGCCACCACGCCTAGCTATTTTGTATTTTTAG TAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCCAGCCTCAGGTGATC TGCCTGCCTCGGCCTCCCAAAATGCTGTTATTACAGGCGTGAGCCACCACGCCCAGCCTT CATCTTTTAATGAATGTACATGTATGTAATCTTTTAGGTGAACTTTTTGTAATGTTGTGC CAAGTTCCTTAAAAAGCCCTTTTGGAAGCTGGGCAGGTGGCCCACGCCTGTAATCCCAGC ATTTTGGGAGTCTGAGGCAGGTGGATCACTTGAGGCCAGGAGTTCAAGACTAGCCTAGCC AAAATGCAAAACCCTGTCTCTACTAAAGATACAAAAATTAGCCGGATGCGATGGCACATG CCTGTAATCTCAGCTACTCGGGAGGCTGAGGTAGAAGAATCGCTTGAACCGGGGAGGCAG AGGTTGCAGTGAGCCAAGATGGCGCCACTGCACTCCAGCCTGGGTGACAGAGGGAGACTC CATCTCAAAAAAAAAAAAAAAAAAAAAGATAAAAAGGAAACCTAAGTACTCTTGGGCTTT GTTAAGGATTTTGTTAAATATACAAAGGATTGCAGGGAAAATTAACTTATTTTTAATATT GAGTATGCTTATCCAAGAGCAAAATAATATTTCTCCATTTATTCAAATCATTTAGGAGCA TCATAGTTTTAACATATGGGCCTTGCACGTATCTTAAATTTATCTCTAGGCATTTTAGGT TGTTCAGTTGTTCTTGTGAATGGGATCTTTTTCTCCAAATAGGATTATTGTTGATATCTG TTGATTATGTTAACTTTGTAGTTTCTGACTTTACTGAACTGTCTTCTTAGATCTAATACT CTTTTCAATTTCATCATATATTTCTCATTCCTATTTTGTTTGGGGTTTTTAGGGCGGGAA TATTAACGGGATAAGAGAGACAAAAGAAAATCTGGAAAAACAATTCATTTTACCTTACAT TGCTTGTGATTACTACCACACTATTACTGGGTTGGAAAAAATTGTGAAATCCCAAGGTGC CTAATAAATGGGAGGTACCTAAGTGTTCATTTAATGAATTGTAATGATTATTGGAATTTC TCTTTCAGTGAGAAGCTCTTCATGGAGATGGCAGAGCTCATGGTCTCAGAAGGCTGGAAG GATGCAGGTTATGAGTACCTCTGCATTGATGACTGTTGGATGGCTCCCCAAAGAGATTCA GAAGGCAGACTTCAGGCAGACCCTCAGCGCTTTCCTCATGGGATTCGCCAGCTAGCTAAT TATGTGAGTTTATAGATAATGTTCTTGTTCATTCAGAGGACTGTAAGCACTTCTGTACAG AAGCTTGTTTAGAAACAGCCCTCATGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAAC ACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAAGAGTTCAAGACCAGCCTGGCC AACATGGTGAAACCCCAACTCTATTAAAAGTACAAAAAATTAGCTGGGCATGGTGGTGAA CGCCTGTAACCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGT GGAAGTTTCAGTGAGCTGAGATCACGCCATTGCACTCTAGCCTGGGCAACAAAAGAGAAA CTCCATCTCAAAAAAAAAAACAAGGAAAAAAAGAAACAGCCCTCATGACACTTAGAAAGT AGAATAGCTGGCTGTTATCTGAACATTGAATTGTAAGGCTTATCAGGTGGACTTTGCATT CCATCAGCAGACAATTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCATTCTGTCTCCC AGGCTGGAGGGCAGTGGTGCGATCTCGGCTCACTGCAAGCTCCACCTCCTGGGTTCATGC CATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGCACCCGCCACCATGCCCAG TTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAAGATGGTCTCGA TCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGA GCCACCGCGCCTAGCCTACAAATGTTTTGTAATAGCTCTTGAGGCCCATCTTGGAGTTCT CCTTTTGCTAAAACCACTGAACTCTCTAGGAGGAAAAAGGAACTTGGTTCTTGACATATG TGTGCATGTATTTCCATATAACCTTTAGGAAGCTATTGCAATGGTACTATAAACTAGAAT TTTAGAAGATAGAAGGAAAATATTCTGGAGATCATTGAAGAGAAATGGAGTCCAACACTA GTTAAAGATGATGAAGACAGATTTTTTTTTTTGACGGAGTCTCGCTCTGTCGCCCAGGCT GGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCCTCCACCTCTTGGGTTCAAGTGATT CTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCACACCACCACGCCCGGCTAA TTTTTGTATTTTTAGTAGAGACAAGGTTTCACCATATTCGCCAGGCTGGTCTCGAACTCC TGACCTTGTAATCCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCAC CACGCCCGGCCGATGAAGACAGATTTTATTCAGTACTACCACAGTAGAGGAAAGAGCCAA GTTCAATTCCAAATACAACAAAGACAGGTGGAGATTTATAGCCAATGAGCAGATTGAGGG GGTCAGTGGATGGAATATTTAAGAAGACATCAAGGGTAGGGAGCTTCTTGCTAAAGCTTC ATGTACTTAAACAAGAAGGGTGGGGGATGAGGGAAATTGATCAGATATCAATGGTGGCAG TATTGACTTAGCAGGATTCTTGCTAAGAGGTCTTGCTAGGACAGACATAGGAAGCCAAGG TGGAGGTCTAGTCGAAAAGAAGGCTCATCAGAGAAGTCTAACTAAAGTTTGGTCAAGAAG AGTCTTTGTCAAGGTAAATCTATCATTTCCCTCAAAAGGTAATTTTCAGGATCCCATCAG GAAGATTAGCATGGCTGCTAGCTTTCTCCTCAGTTCTGGGCTATAGCTCACATGCCTAGT TTGAACTAGCTCAGCAGAACTGGGGGATTTATTCTTTGTCTTCCAACAAACTCATCTGGA TGATTTTGGGGGTTTGTGGGGAAAAGCCCCCAATACCTGGTGAAGTAACCTTGTCTCTTC CCCCAGCCTGGAATGGTTCTCTCTTTCTGCTACCTCACGATTGTGCTTCTACAATGGTGA CTCTTTTCCTCCCTCTCATTTCAGGTTCACAGCAAAGGACTGAAGCTAGGGATTTATGCA GATGTTGGAAATAAAACCTGCGCAGGCTTCCCTGGGAGTTTTGGATACTACGACATTGAT GCCCAGACCTTTGCTGACTGGGGAGTAGATCTGCTAAAATTTGATGGTTGTTACTGTGAC AGTTTGGAAAATTTGGCAGATGGTAATGTTTCATTCCAGAGATTTAGCCACAAAGGAAAG AACTTTGAGGCCATGGTAGCTGAGCCAAAGAACCAATCTTCAGAATTTTAAATACCCTGT CACAATACTGGAAATAATTATTCTCCATGTGCCAGAGCTCCCATCTCTTCTCTTTCAGTT CATTAATTAATTAATTAATTCATGTAAAATCCATGCATACCTAACCATAGCTAATATTGT GCACTTATAATTCAAGAGGGCTCTAAGAGTTAATTAGTAATTGTAACTCTCTATAACATC ATTTAGGGGAGTCCAGGTTGTCAATCGGTCACAGAGAAAGAAGCATCTTCATTCCTGCCT TTCCTCAATATACACACCATCTCTGCACTACTTCCTCAGAACAATCCCAGCAGTCTGGGA GGTACTTTACACAATTTAAGCACAGAGCAACTGCCTGTCCCTGCTGCTAGTTTAAACATG AACCTTCCAGGTAGCCTCTTCTTAAAATATACAGCCCCAGCTGGGCATGATGGCTCATGC CTGTAATCCTAGCACTTTGGGAGGCTGAGGCGGGTGGATTACTTGAGGTCAGGAGTTCGA GACCACCCTGGCCAACATGGTGAAACCCCATCTCTAGTAAAAATACAAAAATTAGCTGAC TTTGGTGGCACATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGACAGAAGAGTCACTTG AACCTGGGAAACAGAGGTTGCAGTGAGCCAAGATCGCACCACTGCACTCCACCCTGGATG ACAGACTGAACCCCATCTCAAAAAATTAAAATAAAATAAAATAAAATAACTATATATATA GCCCCAGCTGGAAATTCATTTCTTTCCCTTATTTTACCCATTGTTTTCTCATACAGGTTA TAAGCACATGTCCTTGGCCCTGAATAGGACTGGCAGAAGCATTGTGTACTCCTGTGAGTG GCCTCTTTATATGTGGCCCTTTCAAAAGGTGAGATAGTGAGCCCAGAATCCAATAGAACT GTACTGATAGATAGAACTTGACAACAAAGGAAACCAAGGTCTCCTTCAAAGTCCAACGTT ACTTACTATCATCCTACCATCTCTCCCAGGTTCCAACCACTTCTCACCATCCCCACTGCT GTAATTATAGCCTAAGCTACCATCACCTGGAAAGTCATCCTTGTGTCTTCCCCTTTATTT CACCATTCATGTCCTGTCTATCAACAGTCCTTCCACCAGTATCTCTAAAATATCTCCTGA ATCAGCCCACTTCCTTCCATCTTCACTACATGCACCCTGGCCTTCCAAGCTACTATCGGC TCTCAACCAGACTGCTGGGACCACCTGATCTCTCTGCTTCCACTCTGTCTCAACCCCCAT CTATTTTCCAAGCAGCACTAGAGTTATCATATTAAAATGTAAATATCAGTTTTTTTTTTA AAGAAAAAAACCCTGAGACTTAACAGAGTTATAAAAAATATAAATGTCATCATCAGTTCC CTGCTTAAAACCCTTAACTCGCTTCCAATTGCACTTGGAATGAAACCAAACTGCACTGAT CCAGCCCTTGCCTGCCTCCCCAAAGTCCAAGGGGTCATGGCTCTTTCCCTGGCTACACTG GTTTTCTTTCTGTCCCTCAACACTGCAAGCCTATTGCTGCCCCAGGGCCTTTACACTTGC TTTTTTTCTGCCTAGAACAGTTCTTCCCCAAAGATTTTTAAAGGGCCGGGCTCCTTAACA TTGAAGTCGCAGACCAAACGCCACATATGCAGACAGTTCTTCTCTAACTACTTTAAAATA GCCCTCTGTCCATTCATTCTTCATCACATTAACCTGTTTAATTTTCTTCTCAGAGCTCCA CACTATTTGGAAGTATTTGTTGACTTGTTACCATGTCTCCCCACTAGAGTGTAAGTTTCA TGAGGGCAGGGACCTTGTCTGACTTTGACTGTATCTCTCGCATATGGTTAAGTGTTGAAT AGTTATTTATGGAATGAATCCCTATTATTCCCTCATTATCTCTGCAAAATAGTCTTTTTT CTCAACATCTTAAACCTGATATCCCACCTGCCTATCTACAAACTTTTTTTTTGCGACAGA GTCTCACTGTCACCCAGGCTAGAGTGCAGTGGCGCCATCTCGGCTCACTGCAACCTCCGC CTCCCGGGTTTAAGCGATTCTCTTGCCTCAGCCTCCCAGTAGCTGGGATTATAGGCGTGC GCTACCACATCTGGCTAATTTTTGTATTTTTAGTAGAGATGGTTTCACCATGTTGGCCAG GCTTGTCTCGAACTCCTGACCTCAGATGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGG ATTACAGGCATGAGCCACCGTGCCCAGCCTCTACAAACTTTTTATTCCATTAACAAACTA TATGCCTGGGATTTAAGTTTTCTTAATACTTGATGGAGTCCTATGTAATTTTGCAGCTTT TAATTTTACTAAGACCATTTTAGTTCTGATTATAGAAGTAAATTAACTTTAAGGGATTTC AAGTTATATGGCCTACTTCTGAAGCAAACTTCTTACAGTGAAAATTCATTATAAGGGTTT AGACCTCCTTATGGAGACGTTCAATCTGTAAACTCAAGAGAAGGCTACAAGTGCCTCCTT TAAACTGTTTTCATCTCACAAGGATGTTAGTAGAAAGTAAACAGAAGAGTCATATCTGTT TTCACAGCCCAATTATACAGAAATCCGACAGTACTGCAATCACTGGCGAAATTTTGCTGA CATTGATGATTCCTGGAAAAGTATAAAGAGTATCTTGGACTGGACATCTTTTAACCAGGA GAGAATTGTTGATGTTGCTGGACCAGGGGGTTGGAATGACCCAGATATGGTAAAAACTTG AGCCCTCCTTGTTCAAGACCCTGCGGTAGGCTTGTTTCCTATTTTGACATTCAAGGTAAA TACAGGTAAAGTTCCTGGGAGGAGGCTTTATGTGAGAGTACTTAGAGCAGGATGCTGTGG AAAGTGGTTTCTCCATATGGGTCATCTAGGTAACTTTAAGAATGTTTCCTCCTCTCTTGT TTGAATTATTTCATTCTTTTTCTCAGTTAGTGATTGGCAACTTTGGCCTCAGCTGGAATC AGCAAGTAACTCAGATGGCCCTCTGGGCTATCATGGCTGCTCCTTTATTCATGTCTAATG ACCTCCGACACATCAGCCCTCAAGCCAAAGCTCTCCTTCAGGATAAGGACGTAATTGCCA TCAATCAGGACCCCTTGGGCAAGCAAGGGTACCAGCTTAGACAGGTAAATAAGAGTATAT ATTTTAAGATGGCTTTATATACCCAATACCAACTTTGTCTTGGGCCTAAATCTATTTTTT TCCCTTGCTCTTGATGTTACTATCAGTAATAAAGCTTCTTGCTAGAAACATTACTTTATT TCCAAAATAATGCTACAGGATCATTTTAATTTTTCCTACAAGTGCTTGATAGTTCTGACA TTAAGAATGAATGCCAAACTAACAGGGCCACTTATCACTAGTTGCTAAGCAACCACACTT TCTTGGTTTTTCAGGGAGACAACTTTGAAGTGTGGGAACGACCTCTCTCAGGCTTAGCCT GGGCTGTAGCTATGATAAACCGGCAGGAGATTGGTGGACCTCGCTCTTATACCATCGCAG TTGCTTCCCTGGGTAAAGGAGTGGCCTGTAATCCTGCCTGCTTCATCACACAGCTCCTCC CTGTGAAAAGGAAGCTAGGGTTCTATGAATGGACTTCAAGGTTAAGAAGTCACATAAATC CCACAGGCACTGTTTTGCTTCAGCTAGAAAATACAATGCAGATGTCATTAAAAGACTTAC TTTAAAATGTTTATTTTATTGCC OMIM ID 300644