| Entrez gene ID | | 26357 |
| Official gene symbol | | Abcg2 |
| Full name | | ATP-binding cassette, sub-family G (WHITE), member 2 |
| Aliases | | ABC15,ABCP,AI428558,BCRP,Bcrp1,MXR,MXR1 |
| Gene summary | | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. [provided by RefSeq] |
| Location | | Chromosome: 6 Locus: 6 B3|6 28.5 cM |
| Gene position | | 58546666 - 58642445 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 95780 bp |
| Gene sequence |
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