| Entrez gene ID | | 25367 |
| Official gene symbol | | Adarb1 |
| Full name | | adenosine deaminase, RNA-specific, B1 |
| Aliases | | Adar2,Red1 |
| Gene summary | | This gene encodes a double-stranded-RNA-specific adenosine deaminase that is involved in editing pre-mRNAs by site-specific conversion of adenosine (A) to inosine (I). Substrates for this enzyme include ionotropic glutamate receptors (GluR2-6) and serotonin receptor (5HT2C). Studies in rodents have shown that this protein can modify its own pre-mRNA by A->I editing to create a novel acceptor splice site, alternative splicing to which results in down regulation of its protein expression. Additional splicing events result in transcript variants encoding different isoforms. [provided by RefSeq] |
| Location | | Chromosome: 20 Locus: 20p12 |
| Gene position | | 11616717 - 11747293 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 130577 bp |
| Gene sequence |
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