| Entrez gene ID | | 23435 |
| Official gene symbol | | TARDBP |
| Full name | | TAR DNA binding protein |
| Aliases | | ,ALS10,TDP-43, |
| Gene summary | | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq] |
| Location | | Chromosome: 1 Locus: 1p36.22 |
| Gene position | | 11072679 - 11085549 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 12871 bp |
| Gene sequence |
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| OMIM ID | | 605078 |
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