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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SIRT3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 23410 Official gene symbol SIRT3 Full name sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) Aliases ,SIR2L3, Gene summary This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq] Location Chromosome: 11   Locus: 11p15.5 Gene position 236362 - 215030  Map Viewer Gene orientation minus Gene size 21333 bp Gene sequence >SIRT3:complement(155030..176362):Length=21333 GCGAGTCCGGAGGACTCCTTGGACTGCGCGGAACATGGCGTTCTGGGGTTGGCGCGCCGC GGCAGCCCTCCGGCTGTGGGGCCGGGTAGTTGAACGGGTCGAGGCCGGGGGAGGCGTGGG GCCGTTTCAGGCCTGCGGCTGTCGGCTGGTGCTTGGCGGCAGGGACGATGTGAGTGCGGG GCTGAGAGGCAGCCATGGGGCCCGCGGTGAGCCCTTGGACCCGGCGCGCCCCTTGCAGAG GCCTCCCAGACCCGAGGTGCCCAGGGCATTCCGGAGGCAGCCGAGGGCAGCAGCTCCCAG TTTCTTCTTTTCGAGGTATTTTGGGCAAGGACAAGCACTTCTTGCGTGTTCGTTGTCGAC ACCTCGCCCACTCTTTCTCACCTTGCCGTGTTTCCTTTGCGGCATGTCTGGGAGTTTACG TGCGTTCCAACACCGGGGCCTCCGTCTTTATGCTGATCTGTGGACGTCACTTATGGGGGT TTTGTCGTTTATTTCACCATTCCCTCATTGAAATACGTTCTAACCTTTAGTTATTGTGCA TCATGCTGTGGTGAATAACCTTGTTGGCACCTCACTGTTTGCATAAATTCCTAGTACTGG GATTGCTAGGTCCAAAAGTATATGCATTTAACGCTTTAATGATCCCTCATAAATGTTGTG CGGTTAATACTCCCACTGGCATGTGATCGTACCCGTCTCCATAGTAATTGCATCTAAGAA CTGAGGCTACATAGGAAAAAATCTTAAGGTCCATGGTTGTTAGGTATCAGATGCCCTATA ATGGATGAATATTTAAGTAAATAATGGCACATTGACTTGCTGTCTGACACAACTGCTGAA AATGTTGGTGAAAAGTGAGTCTCGAAGTGGTAGCTCACACTTGTAATACCAGCACTTTCG GAGGCTGAGACGGGGATCGCTCGAGGCCAGGAGTTCAAGAGCAGCCTGGGCAACATAACG AGACCCCCATCTCTACCAAAAATTTAAAAATTAGCCGGGCATGGTGGCGCAAGCCTGTTG TCCCAGTTACTCCTGAGACTAAGGCAAGAGGATCCCTTGAGTCCAGGAGTTCAAGGCTGC AGTGAGCTATGATTGAGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTTATCTA CCTGTGGGAAAAAAAAAAGAAAAAAGTTTAATAGATCCTGAAGAGTTGGCCGGGCGCGGT AGCTCACGCCTGTAATCCCAGCACTTTGGGAGGATGAGACGGGTGGATAACGAGGTCAGG AGTTCGAGACCAGCTGGGCCAACATGGTGAAACCCCATTTCTACTGAAATTACAAAAATT AGCCGGGCGTGGTGGCGGGCGCCTGTAATCCTAGCTACTCAGGAGGCGGAGGCAGGAGAA TCACTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCCGAGATGGCACCATTGCACTCCAGC CCGGGCGAAAGAGCAAAAACTCCGTCTCAAAAAAAAACAAAGATCCCGAAGAGTCAGTCG TTCATCCAAGAAGCCCTGACTGAGCTCTTATTCTGTGCCAGACTCTGTTCTAGGTGCTAT GGATGGAGCAGGGACCAGGACCTACAAACACGTGGAGCGCATTCTAATATCTGTGATACT CTGCAAAACTGTTAAAACAAATCCTTGCGGCCGGGCGCGGTGGCTCACGCCTGTAATTCC AGCACTTTGGAAGGCCGAGACGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGC TAACACAGTGAAACCCCGTCTTTACTAAAAATACAAGGAAATTAGCCAGGCGTGGTGGCG GGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAG GCGGAGCTTGCAGTGAGCCGAGATCGCGACACTGCACTCCAGCCTGGGCAACAGAGCGAG ACTCCGTCTCAAAACAAAACAAAACAAAACAAAACAAAAATCCTTGCTACCACTGGCCCT AAAGCAGGAGGCATAGGGCTGCGTGTGAGGAGTAGTCCATTGCATGGGCTTCCTCCAGTT TGGCTTTGGATTTTTGAGCTCTCTGAATTTGTTGTTTGTGTCCTTTGCACAGTGTCCCTC CCAGGTTGCACCCATGCCTGCCCCTCAGGGTCCCCCACTCCCAGTGAATTTCACACCATG CAGCATGTACTTTAAGCCATACATCTTACGTATGTTCCAGACATTTGGTAAAACGCCGTT TATGTGTTTTTCAGTGACTCACAAACATTTTATTTACGTAAATGAGGAATGTACTCAGGC ACCCTTCGTGATACCTTGCCCTCAGCAGGCACTCAACAGCAATAATAACTTTCATTCCTT TTGTGCTTCTCTTAACAGTTCGTGTTTAGTAGGAGCACAGTAGCTGTTTGGGGAACGACC TTAAGTGAATAGATGTCTGAAATGCTGTGTGAAGTGGGGCGCTTAATAGGTGGTGAGATG GTTTTAGAACCAGGGTTTTCCCTCTTTGCTTCTTGACTCCTTAACCAGTTTTCATTAGGA GACCCCTTTGGAGGTTTGCAGTCAGTCAGAGTTGAGTGCCTACTGAGTGTACTGAATTAT GAAATGAGCACAGTTCCCATTAACCTGAATTTTTTGCTCCCAAGTAAGTCTTGATTTCTG ATTTATGACTGCTTTTTGTTGTACCCCAATAGTCGTCTAAGAAAGGTGATTATTTTGAGA GGCCTGGGGAGACACACATGCTCATTCTCGAGGGTGGCGGTGGTGCAGAGGGCAGAGCCA TGCTCGTTCTTGCTATCCTGAGATTGGTTGCTATCTGTTTCCTTTGCTGCTGTGTTTTTT TCTGTCAGTATTAAAGGTGGAAGAAGGTCCATATCTTTTTCTGTGGGTGCTTCAAGTGTT GTTGGAAGTGGAGGCAGCAGTGACAAGGGGAAGCTTTCCCTGCAGGATGTAGCTGAGCTG ATTCGGGCCAGAGCCTGCCAGAGGGTGGTGGTCATGGTGGGGGCCGGCATCAGCACACCC AGTGGCATTCCAGACTTCAGGTACTGCCCACAGTCCCACCTGCCTTCTGCGCTCCCCTCC CCTGACTCCTGCCCTCCCCACTGCCCAGTTTATTCCACTTCCCTGTCCTCTTCCAAAGGC CTCAGAGCCTTTCTTCTCTCCCTGCAGATCGCCGGGGAGTGGCCTGTACAGCAACCTCCA GCAGTACGATCTCCCGTACCCCGAGGCCATTTTTGAACTCCCATTCTTCTTTCACAACCC CAAGCCCTTTTTCACTTTGGCCAAGGAGCTGTACCCTGGAAACTACAAGCCCAACGTCAC TCACTACTTTCTCCGGCTGCTTCATGACAAGGGGCTGCTTCTGCGGCTCTACACGCAGAA CATCGATGGGCTTGAGAGAGGTGAGCCCTCTGTGAGTCGCACACATTCTTTTTCTCCCAC GGAGGCTCGGGTGCCTGTTTCTCCCAGGGAGGCTCGGGTGCCTGTTTCTCACAGGGGATG CTCGGGTGCCTGTTTCTGGGGACGGCCAAAACCTATCGCTTATGCTTCTTCCTTGGGACT TTTTTTGAGCCAACTAGTTAGGGCTTTGTTCCCAAGGAAAATGTCCTCTGGGTGTTTAAA GGCCACTGCTTGTTCTCCTGCATACCTGCAGAGCTGTGTATTTTGGGCAGAAGTTGACAT TGTTTTGCCAATCTGGTGTGATGATCTCTTTTTTTCTTCTCTCTTTTAAGAAGTGTATTA TGGAATTTTTTTGAGCACACACAAAGAGAGCAATGTAACGAACCGTCCTGTCCTCATCAC CAGCACACAGCCAGTTCTTCCTGCGTCCTCACCACCTTCTTCCAAATCCCCAGATTATTT TGAAGCAAATCTCTCACATCATGAATTTAATCTAGAAATAATCTATAAACACATGAATGG ATAGCTCTAGAGAATACTTTAAAAACAACTCCGGCCGGGTGCCGGATTACAGGTGTGGGA TCACACCTGTAATCCCAGCATTTTGGGAGGCCGAGGCAGGTAGATCACCTGAGGTCGGGA GTTCGAGACCAGCCTGGCCAACGTGGCAAAACCCCGTCTCTACTAAAAATACAAAAAATT AGCCAGGCGTGGTGGTGTGTGCCTGTAATCCCAGGTACTCGGGAGGCTGAGACAGGAGAA TCTCTTGAACCCAGCAGGCGGAGGTTGCAGTGAGCCGAGATCGTGCCACTTCACTCCAGC CTGGGCGACAGAGGGAGATTCTGTCTCAAAAAAATAAATAAAAATAAAAATAATTAAAAA ATAAAAACAACTCTGATAGTGATTCACACTGAAGAATCACTAGTAATTCCTTAATATGGT CACACTTAGTCTGTGGTGATTTCTTGACCGTATCCATATGGTGCCCAAACCAGCGATTCA CAGGTTGTGCCAACTTCTGGCCGTGCACCTAACGGAAGCACTTGGTGGGGCCTTTTCCTT ACGTGCAGTGATGCAGACAGGTGCTGGGACAGTCAGCTCTCCGGGAGCCAGGCTCCCGGA GAGACTGCTGATGTGTTGTCAGTTAAAAAGAGGTGGCACCTTGGCTCCAGGAATGTGTTT CCTTGCCAGAAGGATCCCCTGACTTGGAACCACAGAGGCAGCAGCGGATGCCCCATGTTG GTGGGCTCTTCTCCCAGAGGTGCAGCAGGGCAGGCCTTGTGGGAAGGTGGGAGCTCCTGG CTGTGAGATTCAGCACTGCTGAGTTAGGGCAGCGACAGGGACTTGGGAAGCCTCCTGCAG CTGGGACCCTGGCTGTGCCACCGCAGCCTTTCAGAACCAGTTAATACTAACACAACTTTC ATAAGAAGTCACTTTTTGTCTGTTTCTACCAAGCAATTCTTTTGGAATTTATGATATTTA TATCCTCATTTTAACTTGGTATCTGTAGAATAGAAGATATGTTCCTGGATATTAGATATA AATTTTTGAGACAGGGTCTTGGCTCTGTTGCCCAGGCTAGAGTGCAGTGGCATGATCATA GCTCACTATAGCCTGAACTCTTGGGCCGAAGTGATCCTTTTGCCTCAGCCTCTGGAATAG CTGGGACTACGGGCATGCACTACCATGCCTGGCTAATTAAAAAAATTTTTTAAGACAAGT CTCACTATGTTGCTGAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCCTCCTGCCTTGG CCTTCCAAAGCACTGGGATTACAGGCATGAGCCACTGCACCCAGCCTGGTATTAGGTGTA ATTTTTTTTTTTTTTTTTGAGACAGAATCTCGCTCTCTTACCCAAACTGGAGTGCGGTGG CACGACCTCAGCTCACTGCAACTTCCACCTCCCGGGTTCAAGCGATTCTCCTGTCTCAGC CTCCCCGAGTAGCTGGCACTACAGGTGCCTGCCACCACATCTGGCTAATTTTTGTATTTT TAGTAGAGGTACGGTTTCACCATGATGGCCAGGCCGGTCTTGAACTCCTAGCCTCAAATG ATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGGGCCACTGTGCCCGGC TGGATATAATTTTATTTGAGCTTTTATCAAATGGTTTTTCGTACTGAGTTTTGACAGGCT TTGTTTTAACCGTGATTTGGCTCCAGCTAGGTGCCCCTTTGCTCCCCTGCCTTATTCTGG TTGATGGCGCATGTAGGTGATACGGGCATGAAAACCAGGCTTGAGGACATCACAACCCCA AGGGGCTGTGCCTCCTTCCAGGAGTCCTGCCAAGCCCAGAAGTTGTGCTCTTGGCCTTGC GTGCTCATCTCGGAGGCGGCAGCAACACTTCGCTTTGGCTTGAATTTCAGTGTCGGGCAT CCCTGCCTCAAAGCTGGTTGAAGCTCATGGAACCTTTGCCTCTGCCACCTGCACAGTCTG CCAAAGACCCTTCCCAGGGGAGGACATTCGGGTGAGTTATCCTGCTGTTGGTTGTCCTTC TGCAGTTTGCTGTTGGGGTGATCTGGAAAAGTGGTATTTTATAAGCATTGTCTCGAAAGG ACAGTTGAACAATAATAGTGTGAAACATTTTATTTGTAAATTAGAAAATCAATACATGCT TGTAAAAAAATTTAAGACAATATAGAAATATGTAGGGAAAATGAATCTCCCTTCAGCCAA TTCCAGCTGCCCACTTTTTTTTTTTTTTTTTGAGATTGAGTCTCACTCTGTCGCCCAGGC TGGAGTGCAGTGGGCGATCTCGGCTCACTGCAACCTCCGTCTCCCGGATTCAAGGAATTC TTCTGCCTCAGCCTCCTAAGTAGCTGGGATTACAGGCGTGAGCCACCACGCCCGGCAATC AGATGGCCTTTTGTGCCGAGCTTATTTCCTGAAAATGTTTCTCGCTCCTTCGCCTTGTAG CTTGTGTTAGTATTTCATCCTGTTTCATGGCTAAATGTTCCACTGATGTATGCACCACAG TTGGTTTGTTTGTACATGGATGGGTGTTTGGGTTGTCCCACCTTTCTGCTCTTGTGTATA GTTCTGCTGTGGAGCATATGCAAGTATTCGTTTGAGAGTCCTTGTTTTTTATTCTTTTGA GTATGATACCTACAAGTATTGCTGGGTAACTCCACGTTTAGCTATATTTATTTATTTATT TTTTGAGACACAGTCTTACACTGTCACCCAGGCTGGAGTGCAATGGCGCGATTTCGGCTC AATACAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGAAGCTG GGATTACAGGTGCCTGCCACCATGCCCAGCTAATGTTTTTTGTATTTCTAGTAGAGATGG GGTTTCACCATGTTGGCCAGGCTGCTCTTGCATTCCTGACCTCAGGTGGTTCACCCGCCT CGGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCACCATGCCCTGCCCATGTTTAACT TTTTTGTTTGTTTGTTTTGAGACGGAGTCTAGCTCTTATCACCAGGCTGGAGTGCAGTGG CGCAATCTCGGCTCACTGTACCATCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGC TTCCTGAGTAGCTGGGACTACAGGCACACACCACCACGCCCGGCTAATTTTTGTATTTAG TAGAGTAGTTTCACCATGTTGGCCAGGATGTCTCGATCTCTTGACCTCGTGATCCGCCTG CCTCTTTCTCCCAAAGTGTGGGATTACAGGCGAGAGCCACTGCGCCCGGCCCGTTTTAAC TTTTTGAGGAACGAATATACTGTTATCTGCAGAAGCTGGACCATTTTACATTCCACCAAC AGTGGGCAAGGGTTTCATCTTTTCCACATCCCAACACTTACTTTCCATTTTTTAATTACA GCTATCCCAGTGGGTGGGAGGTGGTAACCCACTGTAGCACTGATTGGCATTTTCCTAATG ATTCATGATATCAAACATCTTTCCATGTGCTTTTTGGCCATTTGTATATCTTTGGAGATT GAAGTCCTTTGCGCATTGTTTAATTGTGTTGTCTTTTTTATTGTTAAGAGAGTCCTTTAT ATATTCTGGAAGCTAGATCCTTATCAGAGACATGATTTGCAAATATTTTCTGTCATTCTG TAGGTTGTCTTTTTTACTTTGTTGATGTCTTTTGATGCATAGAAGTTTTGATTTTGATGA AATCTAGTTTGTCTATTTATTTTCTCACTCTTTTGGAATCATATCTGAGAAATGGTATTG TTTTACTCCTGTTTTCTTATAAGAGTTTTATAGTTTAAAGCTTTTACATTTAGTTCTTTG ATCCATTTTGAGTTAATTTTTGTGTGCGCTGTAAGGTAGGGATCCAGCTTCATTTTCTTT TATGTGGATATGTAATTGTTCCAGCACCATTTGTTTAAAAAAACTGTGGTCTTGGCATTG TTGTTGAAAATCAGTTGGCCATAGGTGTATGGGTTATTTCTAGAGTCTCAATTCTATTCC ATTGTTATCTGTATATCCTTGTGCCTGCACTATAATGTTTTGGTTACTGTAGCTTTGTAG TAAGTTTTGAAATTAGGAAGTGTGAGTCCAGCACATAGTAGAAACTTGATATATACGTAT TATTGTTTTGGTCAACTCATTCATTGAATGACCAATTTATTCAACAAATAGTTTAGTCTC CTCAGTGCCAGGCCCTTTGCTGGGTTCTGTGGATGTGAATAGAAATTAAAATAAGGTGGA GTCATCCAACAGTTACAACTGGGTGCCATACGAATTTTACTATAAATATGTACTGGACAC TACACTGACTCAGCTGTAGGAACAGAGTAGGCTGGGAAGCACCTTTGAGATGAGGCCGTC TGGATGTAAGAGTCTGTTTCTGGCAGCAGAGACCTGGAGTGTGGGAGGCCTGCTTGCTCT GTTAGGGTTTGAACTGTATCCTGACGATCATGGGAGGCATTGGAGGATTTTTAGGCAGGA AAATGATGTGAAGGGATTTGCATTTAAAAGAGATTATTTGGGACTGGGCACAGTGGCTCA CGCCTGTAATTCCAGCACTTTGGGAGGCCTAGACAGGCGGGTCACCTGAGGTGGGAAGCT TGAGAGCAGCCTGCCAAAATGGTGAAATCCCATCTCTACTAAAAATACAAAAATTAGCCA GGTGTGGTGGTGCACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGAAGAATTGCTTG AACCTGGGAGGGGAGGTTGCTGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGGTGA CAGAGTGAGACTCCATCTCAAAACAAAATAAATAAATAAATAAGAGAATAAAATAGATAA TTTGGGCAACAGGTTGATGTTAATTCCCCACCTTTGTTCTTCTCCTTCAGTACTGTGTTG GCTGGTCTGAATCTTTTGGCTTTTCATATAAATTTCTGAAACTGTTGCTATCTGTTCTCT GCCTGTTTTATTTTTGTTGTTGTTGTTTGGATTTTTTGTTTTTTTGAGATAGAGTCTTGC TCTGTTGCCCAGGCTGGAGTGCAGTGGTATGATCTCAGCTCATTGCAACCTCCCCCTCTC AGGTTCAAGCGATTCTCTTGCCTCATCCTCCTGAGTAGCTGGGATTGCAGGCATGCGCCA CCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACTATGTTGGTGAGGC TGGTGTCGAACTCCTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATGA CAGGCATGAGCCACCGTGTCTGGCCTCTCTGCCTGTTTTTTAAGACTTTTGTCTTTGGAG TTTTGCGGTTTCTCCACTGTGGTTTTCCATATGAATTTTCTTTTATTTCTTCTGCTTAAA ATTTGTAGGCCAGTTGGTCATGGTGGCTCACGCCCGTAATCCCAGTACTTTGGGAGGCCG GGTGGGTGGATCGCCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCC CATATCTACTAAAAATACAAAATTAGCCGGGCGTGATGGTGCATGCCTATAATCTCAGAT ACTCGGGAGGCTGAGGCAGGCGAATTGCTTGAACCAGGGAGGCGGAGGTTGCGGTGAGCT GAGATTAGGCCATTGCACTCCAGCCTGGGAAACAAGAGCGAAACTCCATCTCAAAAAAAA AAAAATAATAATAATAATTGTAGGCCTTCCTTAAGAAAAATAAAATAAAATTCTAGGCTG GGCGCGGTGGCTCCTGCCTGTAATCCCAGTACTTTGGGAAGCTGAGGCGGGTGGATCACC TGAGTTAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAAT ACAAAGATGAGCCATTTGTGGTGGCACCCATCTGTAATCCCAGCTACTCGGGAGGCTGAG GCAGGAGAATTGCTGGAACCCAGGAGGCAGAAGTTGTAGTGAACCGAGATCATGCCACTG CACTCCAGCCTGGGTGACAGAGCGAGATGCCATCTCAAAAAAATAAAATATAAAATAAAA TTCTAAGCCCTGCAACCAACTGAATGGAGCCCTCCCCTTGGTCAAGGGAACCCCAGAGAA ACCTTGGAAGCTTGAGTTCCTGGCCGTAGCAGGAGAGGAGGTCAGACGCGCCTCACTGTA CCCCTCCCTCCCCAGCCACCATTAGGCTTCTTCACTAAGGGCTAAACAGAAACCAGCCCT TTTCAAAGACTCTACACTGCTAATGTGGATTACTGGTTTATCTTCCCAGATACAGATTAA AGACAAGATGAGATTAATGGTTCCTTCACCCTTCCCTGAGAGGTCTGCTTAGTTCTCTTC CTCTGTTTCCTTCTATCTTAGGTAAAATGTACATTTACTGGGCACTTACTGAAGTCTCAC AAGTACGTAACCACTCACCTCACAGCCACCCTCCCTCTTTGAAGGACCACATGTAATTAC TAAACCTCCTGAGAACCTCTTGGGACAGAAACAAGCACAGATGTGCCGTGACTCATGTTT TTCCTGTGGGCACCCTCAGGCTGGCTCAGTAGCCCTCACTTGCTTGAGATCCTGAATCTG CGGGTTGGCGTCTTTCATGGTTGCTGGATCATACTCTGCCGTTATCTCTTCGGATATGAG TTGCCCCTAGCCCACTATCTGGCCCCTCTCTTTAGGGACCTCTGATTGAACATACATTAG ACCTTCTCTCTCCTGCTGTTCCTGATCACTCTTCTGTCCTGTAATTGCTGCTTCTTGTGC TGCATTCTGGGTAATTTCTTCTGGTCTTTTTTCCAGTTTACTAATATTGTATTCTGTTAT AAGGTCCTTCCATTGAGTGTTTCTTTCTTTCTTTTTTCCCAAACAGCAACTCAAAACAGA CATTGAGTTTTAATTTTGGTTCCTGTACTTTTTATTTCTAGAAGTTCTATTTGGTTATTT TTCAAGTCTGCTACATTATTACATAATTTTTTAATAATTTTATATCTTTAATAGATAGTT TTTTGTTTTGTTTTGTTTTGTTTTGTTTTTTGAGACAGAGTCTCGCTTTGTTGCCCAGGC TGGAGTGCAGTGGTGCAATCTCAGCTCACAGCAACCTCCGCCTCCCAGGTTCAAGTGATT CCCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACGCATCACCACGCCTGGCTAA TTTTTTGTGTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAAGACAGTCTCGATCTCC TGACCTCGTGATCTGCCCACCTCGGCCTCCCGAAGTCCTGGGATTACAGAGCTGAGCCAC TGCGCCTGGCCTTTGATAGATATTTCAAGTTCATCTTTTTTTTTTGCTTCCTTAATTTTT TTTTTTGCTATACCCCATGCCTCCAAGATAACAGTTTTTTCTTTTTAATTTAAATATAAT ACAGTTTTACTGTGTATCCAAGAATATCTGAAATCTTTCGTGGGTCTCTTTCTTTTGTCT TTTGTATCTGTTGCTTTTTGCTGGGCTGAGCCTGCTTAAAACAAGCCCCGTTAGCTGTAA AGGTTTACCTTAGAAAGTCAGGTGTCTTCCTCTGTAACTCTCTCCCTTTTCCATCTGCTC CAAGGCATTTATTTATATTAATCTTGACGCAAAGGGAAGTTGTGTCCACTTCACCTTGGC CAGTAAGGAAGCAGTGTTTGGCAGATGTTGTTACTCCTAATAATGCCAGCCAGTGAGTGA AGCTGACCTGAATGCCTCCCAGGGCTGAGGCAATGGCATGATCACCGAAGCTCAAACCAG AGACAGTTTCACCTTTCTGACTGAATAGTGTTCGGTGTAGGCCAAATGCCTGCAGACTAC TGTTTGAGGACTGGTGTGGTCTACCAGGTGTTTCCTTAGCGCCTGGATGTCTCTGGCTGC CATCCCAGGGATAGAGCATGGTGTTAGATACGCTAGATGCCTGCCGAAGTAATTATGGGT GAAACATATGATGTCCAAGATTTGCTTTTAAAGGCTCCAATACCTCCTCCCAGATTCCGG AGGGCTGTGAAACAATTAGCTATGAAAACTGGTAATTCCTGAAGCTGGGTACATGGGGGT TCATGATCCCTCTCTCACCTTTTTTGGGGGAGAATGTTTGAGACTTTAATAAGAACTTGT TGCCTTTTCCTTTTACAGGGTGTTGCAGGCATCTTCCTCAGGCCTGTTTTCTCTGTTTTC CAGGCTGACGTGATGGCAGACAGGGTTCCCCGCTGCCCGGTCTGCACCGGCGTTGTGAAG CCCGACATTGTGTTCTTTGGGGAGCCGCTGCCCCAGAGGTTCTTGCTGCATGTGGTTGAT TTCCCCATGGCAGATCTGCTGCTCATCCTTGGGACCTCCCTGGAGGTTTGTCAGCAGGCC TGTGCAGGGAGGAGGCTGGAGGGCAGGGGAAGGGAGGGGTACAGGAGTCATCTCATGGGC TGTCGGCAGGCCTGTGCAGGGAGGAGTCTGGAGGGCAGGGGAAGGGAGGGGTACAGGAGT CACCTCATGGGCTGTCGGCAGGCCTGTGCAGGGAGGAGGCTGGAGGGCAGGGGAAGGGAG GGGTACAGGAGTCATCTCATGGGCTGTCGGCAGGCCTGTGCAGGGAGGAGGCTGGAGGGC AGGGGAAGGGAGGGGTACAGGAGTCATCTCATGGGCCCTTCCAGGGCTGGTGCCACTTTG GGAAGGTGAATGGATTCAGCTGGGGTTCCAGGCTGAGGGAGCAGCAGCCTGTGCAGGAGA CAGGAAGGTGGGAAGCTGCTGGGCTTTGGAGGTGGTATAGGTGTGGGTGGGGCACCACGT GTGAGGAGAAGGGAGAAGGATGGGGGTGTGGGGGCGAGGTGGAGGGGCAGGGCCTCCCAG GTCAGATCAGGAATACTGATGCTGCAGTGGGAGGAGTGATAAATCCACAGGGACTGGCCC GGGGACGTAGCTGCACCCTTGGGGTCAGGGAGGCCTTTGGGGAGTGGAGAGTGGAGCAAG CAGTGCCAGGAGGCTGGTCCTGGAGAAGGTGGAGCTGTGGTCGCCTGAGGGATGGCGAGG AGGGGGACTGGACTCGCAGTCTGTGATGTTTTGGGGACGTGAGAAGGAGGCGTCTGGCTT GGTCTGTAAGGTCAGGGCACTTGCTGGTGAGGCGTGATTTGGGAGGGAGGATGCCCAGCT CGGTTCTGTGTGTGTCTGAGGTGTCGGGAAACATGCCCTGGATGTGTTCAAGCAGCTGTT CTGCGTCTGCGTCTGCAGCTCAGGAAATTCCTAAAAGCTGTGATGAGAGCAAGAAATGAG ACCATGAAGTCAGTGTGTGCGTGACTGGATGTAGGCACCGAGGACAGAAGGGCCAGAAAG ACCTGTGCTCAGAGGGGCCCAGGGCAGCCACAGGGGCCCAGAGCATGTGTTTGTTCAGGC ATTCATTGTGTGCTGGGCCCTGCTCCAGTGCTTTGGACATACACGGTCAGATGTCAGTGT AAGAAGTTATATAGTTTGTTAGGAGATGATTGATGTTATGAGAAAGATAACAAGTAGGAT AGAAAGGCTAGAAGGGTTGGGAACCAGCTGCAGTGTCAAGTCAGGCAGGTGGAGTTGGAT CTAAGAGTTTACCGAGGTGAGGAGGGTCTGGCAGGGGACACTGCACAGGTGACAAGCAGC AAGGAGGGTGGGGCGAAGTCAGCATTGATGGCCACGGGGCTGGAGCAGAGAAGAAGGTGG GGCACAAGTGTCATCTCATGGGAGGCTGGCGCCACCTCAGAAGGTGAATGGGTTCAGCTT GGGTTCCAGGCCAGAGTCTGAAGTTGAGAGGACTCCGTTGGGTGCTGGGCTGTGAGCCCA CCATGGGGGCAAGACTGGGAGCAGCAGACCCAGCAGGGCCCTTGTAGGTAATCACCGGCT GGCACTGGCTGGGGGCCAGGTAAAGCCAGCAGAGGCTGAGGGGTGCTGGAGTCTGGGTGT GTGTGAACGCAGAGTGGGTACGCTGGCACAGTGCATGGGAGGCCGTGGATTCCCAAGGAC CCCAGGGCTGTGGCTGGAGCAGCTGGAAAGACGGAGCCGCCGCTTCCTGAGATGGAGAAG CCTGGTAGGTGGGTTTGGGGGAGCTCAGGAACTCAGCCTTGTTTCCACGGATTTGAGGAT GTGCTGCGGACTGGAGGTGTTGAGCAGGTGGACATGAGTCTGGAGTCCAGGAAGGCCCAG AGGCAGGAGCTGGGGTGCTGGAGTGAGCAGACAGGAGAGCCCAGGGTGTGGACAGACATG AGAATGCCATGCTAGGCCTAGGATGGAGGGACAGACACAGGAGGAGCAGTCAGAGGGGCC ATGGTGGTCAGCACAGTGTGGGCTGAGACCAGCTGACCGTGCTGGCCACCAGGTGTGGAC ACTTGGGCCACCAGCCATCTTTATTGTTGAAGTGAAATGAAAATGGCCTTTTTCCTGATT ATAAGTGTATCATGTGTGTCTTTGAAAAGATTCGTACATTATATAAAGATATAAAGCAAA GGATCAACTTTTTAATCCCACCAACTGTTAGCATTTTATTCTGTGTCCTCTCAGCTTTCT TTTTTTTGTACAAATGCATACGTACAGATGGTAATTTTAAACTAAAAGTTGGACAGCACT GTACATTCTATTCTGCAGCCTGCTGTTTTCACGTAACAATGTGAGTCCATGGAGATGTGC TGCGTTGTTAATGCCAACAGTTTCCCTTACACGGATATGAGGTCCCAACTGAGAAACCCA TGTCTGTAAGGCTGGTGCCATCATGAACTGAATGAGCTGGTGTCACGCACAGACTCTATC TCATGTGCTTTGTGGACGAAATGTTAATGTGTTTGACTGTGGAGTACCACTCCAGATCCC CTTTAGGTGTGACATAACGTGGGATGTAAACCATATGATCTTTTCTAAAATCTCAAAAAT TCTGAAACATATTCAGCCACAAGAGCTTTAACATAGATTTTGTGGATTTAATACAAAATT TATGTAAGCAATTTCTTACTGATGGACAATGATAATAAATAGTATATAATTTTTACATTA AAAGTAATGCTGGGCCAGGCACCGTGGCTCACACCTGTTATCCCAGCACTCTGGGAGGCC AAGGCAGGAAGATTGCCTGAAGCTAGGCATTTGAGACCAGCCTGGGCAGTATAGTCAGAC CTCGTCTCTACAAAAAATAAAAAGATAGCCAGGCATGGTCTGTGTAGTTGCAGCTATTTG AGAGGCTGAGGAAGGAGGATTGCTTGAGCCCAGGAATTTGAGGTTATAGTGAACTATGAT CATGCCACTGCATTCCAGCCTGGGTAACAGAATGAGATCCCGTGCTGTAGTGAATATCCC TGTGTATCATCCTTATCTACTCATGCAAGTACTCCTGAAGGGTAAATGCTGTAGTGAATA TCCCTGTGTATCATCCTTATCTACCCATGCAAGTACTCTGGAAGGGTAAATGCTGATAAA TACTGAGAACTTGCCTTCCGGTGAATATCCCTGTGTGTCATCCTTATCTACCCATGCAAG TACTCCTGAAGGGTAAATGCTGTAGTGAATATCCCTGTGTATCATCCTTATCTACCCATG CAAGTACTCTGGAAGGGTAAATGCTGATAAATACTGAGAACTTGCCTTCCGGTGAATATC CCTGTGTGTCATCCTTATCTACCCATGCAAGTACTCCTGAAGGGTAAATGCTGTGGTGAA TATCCCTGTGTATCATCCTTATCTACCCATGCAAGAACTCCTGAAGGGTAAATGCTGATA AATATTGAGAACTTGCCTTCCAGAAAGATGTAACAATTACACTGCCACAAACTGTGTTTT TATGTAGCCATTTTATCACATCCTCACCAAAACCAAAATCACACAAATCAAATTGGTTAA AAAATGCATGTGTGTGTGTGGAGGGGGGTGCGGATTTTGCCTTTCTGTAGTAAAGAATGA AGTTCATCTTTTCATGTTTATTGCCAGTTGTGTTTCTTCTCTTTGGATTGTATATTTGTA CCTCTTGACCATTTTTCATTGGGTCATTATAAATTAGCAATATAAATTAGTTTTAATTTT AGTATAAATTAAATAATATAATTACATTTTAATGTTAATATAAACTTCTTTCTTTTTTTT TTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGGTTCAGTGGCGCGA TCTCGGCTCACTGCAACCTCCACCTCCCAGGCTCAAGCCATTCTCCTGCCTCAACCTCCC GAGTAGCTCGGATTATAGGTGCGTGCCACCACGCCCAGCTAAGTTTTGTATTTTTAGTAG AGACGTGGTTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGCTGATCTGC CCGCCTCGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAACCACCATGCCCAGCTGTTAA TATAAATTTCATTATAAATTAGCATTATAAATTAGTTCATAAATTATATGTTTATAAATG AGTTTATCAATTAGCAATATAAACTATTGTCATATGTTGTAAATATTTTTGCAGTTTATG ATGATGAGAGGTTTTTAAAAATTTTAAATTTTCTACATAGTAGTTTTATGTAGATACCGA GATAATAGTATTTACATAGTCAGATCTGTCATTTTCCTTTGCCTTATCTGACTTCAGTTT TTACGCCTAGAACGTTCTTCCCTATCCTTACTTGTAAATCCTTAGTTTTCTTCAAGAACT GTTTTGTTTACATTGAAACCTTTAATCCATTTGAATTTTTTTCAGTGGGAGGTAGGAATG GAGTATTTTCCTCCCAGATAATGAGCCAGTTTTAATGCCATTTATTAATGTATCCATTTT TTTACCTTGTTCCTCTTAAAAGAAGCTTTGAGAGCTGTATGAAGAAGCCTGATGGCACCG AGCTAGGCCTCTCTAGAGGCTGGGTGGGGAAGACCATGGAGAGACGTAACAGTAACTCCT GCTCGGGGGCACCAGCTCGTCTGGGTGCCCGATGCTGGTGGTGGCTGTCAGAGCAAGCAG GGCTAGCCAGAGGAGATGGACGAGTCTGTGCTGTTGTCCCTCTGCGTCATGCTGGGAGAC AGCGAGGTGGGGAGGACAGGGAGAACAGAACGTGCTCACAAAGAGGAGGCAGGAAGGTTG GATCCCTGATGAGCCTTGGAACGGAGGTGGGGAAAAGCAAGGATGTGTGGAAACAGCAAG AAGTGGGAGAGAGAGAGAGAGGCGGAGGGGAGAAAACCGTCACGGAGGCCAAGCGGCAGG AGCTCAGCTGAAGAAATGAGATTGGTGGTGGGTTTTCCCTATATCGCAGGCTCTGACTGC CAATCTGCTGCTCCTCCAAGGCCTCGGTGGCTGTGGCATGAAACATCCTGAGGAGCTTGT AAAGTGGACACTGTGCCCCTCACGTTTGGCCCATTTTTCAGGTGGAGCCTTTTGCCAGCT TGACCGAGGCCGTGCGGAGCTCAGTTCCCCGACTGCTCATCAACCGGGACTTGGTGGGGC CCTTGGCTTGGCATCCTCGCAGCAGGGACGTGGCCCAGCTGGGGGACGTGGTTCACGGCG TGGAAAGCCTAGTGGAGCTTCTGGGCTGGACAGAAGAGATGCGGGACCTTGTGCAGCGGG AAACTGGGAAGGTACAGACTGCTGAGGAGGACCATCCAAGGGGCTGCCCTTCTCACTGCT CTAGGGTATGGTCCACCTGATATGGAGCCCCGTTGGTTAACACAGTAACAGTAATAGCTG ATGATGCTGTGAATCCTGCACCAGGCACTACCTGGACCTGACTGGGTGTTACTTTCAATA CCTCCATTTAGAGATGAGGAAACAGATGCTAACAGGCCAAGCAGGGACACGGTCCAGACA CTCAGGGCTGATGAGTCTGTATTCTTAACAGACTATAGGCGTTACCTTCACTCCCTAAAA TAAAGCAGCCAACAGTGTCCCTCTAAGGCCTGGTATGTGATTCTAAGATGATACGGGTTA AAGAACTTTGAGAAGCTAAAGTTCTCTGCATCTATGTGGGATGAAGGCTACATGAGTGAT GCTTTTCGGAAGTAATTGGTATGAGAGCCATTGATCAATTATAATCCGCTGAGGAAAGCC AAAGAGCCTTGATGCTTTCTAAGAGATTTCAAACCGCCTATAAACAAGTGAAGTTACAGA AAATGCAGTTTCCCATAAGAATCATGTAGCATGTGTAGCCTTGATATTAAGGGTTTTCAA TGGGAGGTGGTAGCATTAAGCATTTAAAGTCCAGTGTCATGATTACAGGCAGGTGTAACA CTGTCCAAAGGGGATTTCACCAGTGTATTAGTCTGTTCTCTGGCTGCTCATAAAGGCATA CCTGAGACTGGGTAATTTATAAAGGAAAGAGGTTTAATGGACTCACAGTTCCATATGGCT GTGGGGGCCTCACAATCATAGTGGAAGGCAAAGCAGGAGCAAAGTACTGTCTTACAAGGT GGCAGGCAAGAGGACGTGTGCGGGGGAACTGCCCTTTATAAAACTATCAGATCTTGTGAG ACTTATTCACTATCAGAAGAAGAGTGTGGGAAAGACCCGCCCCCATGATTCAGTTACTTC CACTTGGCCCCACCCTTGACACATGGGGATGATTACAATTCAAGGTGAGATTTGGGTGGG GACACAGCCAAACCATATCAACTACAATATATCACAGTTGATGCTCCTCTTGCCTTCCAA GGCAGATGTCTTAGGAAATCCTGATCCTTTTTCCTTGTCCACAGCTGTGGCTGCCTCATG GCTCAGGGCCATGGGGTCAGCACTCTCCTCACCTCCACCAGTCCAAGACCTCCAACCTCT GGTTGCAGGCTGATTTTTTACCAATCATGGTCACTTCATTATGGAGGCAGGGAACCCAGC TAACAATGAGGCTTAAACGCTGAGAGGCGAGTGCCTCCTGGCCAGCTCACAAGGCAGCGG AGATCTTAGATCAGCCCAGCAGGCTTTTTTGAGGGATCCTTTTCCTGCTCCAACTTCATA TTTTCTTTTTTTTGTAATGGAGTTTCACTCTTGTTGCCCAAGCTGGAGTGCAATGGCACG ATTTTGGCTCACTGCAGCCCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCT GAGCAGCTGGGATTACAGGCATGTGCCACCATGCCTGGCTAATTTCTGTACTTTTATTAG AGATGGGATTTCATCATGTTAGTCAGGCTGGTCTCAAACTCCTGACCTCGGGTGATCCAC CTGCCTCAGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCAGCAGGCCCGGCCCAACT TCCTGTTTTCATAGAAAAGCAGATTGTAACTCTGGTAGCTCCTGTGGAGTTTTGGAAGTG GCTTAATAGGATTTGAACTGTATAATCTAGTTTCAGAGAAATGTATGTAAAATGGGTTAT GATTTCATTTTCTGTTTTTTACAGCATTACTATCCAAGGGGTTACTTTTCCAAATAGTGA ATGCTTTTAAGCACATGAGCATCAGTACATATTGATTTGGGTACTTTAAGACCCATAGAA TGAGGCTCTCCATTTAGCCACCCTGTTCTGCCCAGGCCTGCTGGGATCCTCTTAGCCCAG CACAGCAGCAGCAGTATTTGCAGAAAGCAGCTTGTTTTGTGAAATATTTTGCATGTCTGC AGCTAGAGCTGTTTGAACAGAGATCTGCTGGCCTGCCTGGGTGTGTAAACAGATAGCTGA TACCCTCTGTCTTCTGTATTCCAGCTTGATGGACCAGACAAATAGGATGATGGCTGCCCC CACACAATAAATGGTAACATAGGAGACATCCACATCCCAATTCTGACAAGACCTCATGCC TGAAGACAGCTTGGGCAGGTGAAACCAGAATATGTGAACTGAGTGGACACCCGAGGCTGC CACTGGAATGTCTTCTCAGGCCATGAGCTGCAGTGACTGGTAGGGCTGTGTTTACAGTCA GGGCCACCCCGTCACATATACAAAGGAGCTGCCTGCCTGTTTGCTGTGTTGAACTCTTCA CTCTGCTGAAGCTCCTAATGGAAAAAGCTTTCTTCTGACTGTGACCCTCTTGAACTGAAT CAGACCAACTGGAATCCCAGACCGAGTCTGCTTTCTGTGCCTAGTTGAACGGCAAGCTCG GCATCTGTTGGTTACAAGATCCAGACTTGGGCCGAGCGGTCCCCAGCCCTCTTCATGTTC CGAAGTGTAGTCTTGAGGCCCTGGTGCCGCACTTCTAGCATGTTGGTCTCCTTTAGTGGG GCTATTTTTAATGAGAGAAAATCTGTTCTTTCCAGCATGAAATACATTTAGTCTCCTCAA AGGGACTGCAGGTGTTGACATGAGTTGGAAAGGGAACCCTGGGATACGTGGCGTCCCCTC TATTGGAACAGTCTGAGGACTGAAGGCATTTGTCCCTGGATTTATTGGAGACGGCCCAGC TCCTCCCTCTGAAGGTGGTCACATTCTGTTGACTCTCCATACTCAGCCTCTCCTCCAGAA ACAGATCTGTTCCAGAACATTCCAGCACTTTCTATCTGGCCTCCTTGTCCCCACACTACG CCCCCCCACCCTCGCCAGGGCTTCCTCTAGTGACACTGTTAGAGCTAATCTCTGAGACAG GGAAGGCATTACTCACTTAAAACCCAGGCTGAGTCCTGGCCACCTGCTGGATTGTGACAT AGGAGGTGGAATCCACTGAACTGCTACTTCTGCACAGGCTCCTTCTCCTGGGGCTGTACC CAGGCCCAGCCCTGATGGCTCACCCTGTCAGGCACCAGCTGCTCCCTCCTGGGCTCTCAC CCACCTGCACATCCTCCTTCCTAGCATCACATTACCTGCGTGTTTCCCCAGACAAAAGCA CTTCCCATTCTTGAACCTTGCCTACCCTGGGCTGAGCTGACGGCAATAGATTTAATGACA GTGACTCCCAGGAAGGGGGTCCTGTGACTTTGCGCCTTAATAAGAACAAAAGGTGGAATT GGTGACCTAGGAAAACTGTTGAATTCTAAAAAGAATGAAGTTAGTTTCTAACCCTAGTTA ATGTTCCTTTTTTATTTTTTGAGTCTTGCCCTGTCACTCAGGGTGGAGTGCGGTGTTATG ATCTCAGCTCACTGCAACTTCCGCCTCCCGGGTTTAAGCGATTCTCCTGGGTAGCTGGGA TTACAGGTGTGTCCCACCACACCTAGCACATGGGCATATTTGTAATAGAGACAAGGTTTT GCTATGTTGGCCAGGCTGGTCTCGAACTCCTGGCTTCAAGTGATCCACCCACCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCTGGCCCCTTTATTTGATAATTT ACACATACATTTTTGTCCAAAACTCTTCTTTATTTCAAGATGATGTTTCTGTGGCTATGT GTGGTATGTGGTATAAATCTCAATCTATGGTCA OMIM ID 604481