| Entrez gene ID | | 23365 |
| Official gene symbol | | ARHGEF12 |
| Full name | | Rho guanine nucleotide exchange factor (GEF) 12 |
| Aliases | | ,DKFZp686O2372,KIAA0382,LARG,PRO2792, |
| Gene summary | | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| Location | | Chromosome: 11 Locus: 11q23.3 |
| Gene position | | 120207946 - 120360645 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 152700 bp |
| Gene sequence |
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| OMIM ID | | 604763 |