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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SNX13 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23161
Official gene symbolSNX13
Full namesorting nexin 13
Aliases,KIAA0713,RGS-PX1,
Gene summaryThis gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p21.1
Gene position17980131 - 17830385  Map Viewer
Gene orientationminus
Gene size149747 bp
Gene sequence
OMIM ID606589