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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SIRT2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 22933 Official gene symbol SIRT2 Full name sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) Aliases ,SIR2,SIR2L,SIR2L2, Gene summary This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13 Gene position 39390502 - 39369195  Map Viewer Gene orientation minus Gene size 21308 bp Gene sequence >SIRT2:complement(11637413..11658720):Length=21308 AGAGTATTCGGGAGGACTACAACTCTCTAGCCGTTCCCACATTTTCCGGGCGCCCTTTAC CAACATGGCTGCTGACGCCACGCCTTCTGGGACTCGTAGTCCGGTCCTCGCGCGCTTTCT TACCTAACTGGGGCGCTCTGGGTGTTGTACGAAAGCGCGTCTGCGGCCGCAATGTCTGCT GAGAGTTGTAGTTCTGTGCCCTATCACGGCCACTCCCATTTCTGGTGCCGTCACGGGACA GAGCAGTCGGTGACAGGACAGAGCAGTCGGTGACGGGACACAGTGGTTGGTGACGGGACA GAGCGGTCGGTGACAGCCTCAAGGGCTTCAGCACCGCGCCCATGGCAGAGCCAGACCGTG AGTCGGGGATCCGGGTAGGAGGGTCGGGCCGCGCCGGGGCCTGGCTGAATGCTGCAGGCC CCGGGGCCCAAGGGTGGCCGCGGTGGGGCGGGAAGTAGGGAGCGCTTCGGGGAGTGGGAT TCTGAGGGCTGTTGCTTAGCGATCTGTATCGCTAGGCTGGTGGGTTTCTGGGTCGCAGTG TGTTCAGGGTTCGTTTACCACATCCACTTGCCAAGTTGCCAATGATCGCGTGTTTCTCGC ACCTTGGTTGCTAAGGTCCCTCGCTGCAAAGAACATAAGTTGCCCCGGTCCCGCTTGCTA TGGGTACCTGATTGTTAGAGGCAACCAGAGGATGCTGAGGGACCCCTGCTGACCCCTCCT ATGGCTTCCCCTTGTTCCGCGCCTCTCCTAAACCTACCGCCTCCACTGCACCACTGCACC TCCCTCCTAAACCTGCCTCCCAGCCAAAGCGTCTCTTCCCTTCTCTTTTCCTTTCTAAAC TTCCCTCTGCCTTGTAAATCTAACCCTCCCCGCACACACACTCACACACTGTCGTGTCCT TCCTAACTCCTCCTGAGTGTTCCTTCATGCCCTGAATCCCCTAGGTAGGAGGAGGAGGAT CGCTTGAGCCCAGGAATTTGAGGCTGCAGTGAGCTATGATCGCACTATTGCACTCCAACC TGGGTGACATGAGCGAGACCCTTTCTCTAAAAAGTAAAAAAGAAAGAAAGTAAGTCAGGG CCAGAAACAATGGCTCATGCTTGTAATCCCAGTACTTTGGGAGGCCAAGGTGGTTGGATC GCTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAAAAGCCCCTACTTTCTCCCTGTCCCC CTAAATCTTCCTCTCCAGCCTCTCTGCCCCTCACTAATCACCTCTCCCGGCATCACTTTG CATGTAGATAAGATCTTTTCTCCGTCCCCTCCCTCCCTCTGCTCCATTTTTACCACCATC CCATCCCAGTGTAACTAGGTTGGTGGGTGTTCTTGCCCCCTCACTGACCATTTGAACCCC TTTATTCCCCCCTTAATCGTTCTCCCCACTGTAACCACCTCTGCTCCCCTCCCCCAGCCT CTCACCCTCTGGAGACCCAGGCAGGGAAGGTGCAGGAGGCTCAGGTGAGATGGGGGAAAG GGTGGAGGGGAGGAGAGAGACGGACTTGTTCCACATCCCACACTGGGGGGAGGTGGCAAA GGGGAAACAGTCACCCCAGGGCCCTCGGCTCATTGCCCCAATCCCTCACACCACCCAGTG CAGCTTTCTGGGGAAAGGCAGATTCTGGGGATTGTCAGAGAAGAGTTTCCAGCCTCAAGT CCAGGCCTGTCCTCCCAAACTTTCCTTCTTCCTTGCCACTGCCTGCCATCCCTTCTGAAC CACATTTGTCCTGGGACTGGAAGAGACAGGTATCCCATTTGGTCTTGGAACGCACAGATC TCGTGGACAAGTGATGGGAAAAAATGATCTCACAGCGTGATGACGAAAGTAACTCAGGGG GCCAGATGCAGTGGCTTATGCCTGTAATTCCAATAACTCAGGAGACTGAGGCGCGAGGAT CGCTTGAGCCCAGGAGTTTGAGGCTGCAGTGAGCTATGATTGCATCACTGCACTCCAGCC GGGGTGAAAGAGCAAGACCCTTTCTCTAAAAAGTAAAAAAGAAAGAAAGTAACTCAGGGC CAGACACAGTGGCTCATGCTTGTAATCCCAGTACTTTGGGAGGCTGAGGTAGGAGGATCG CTTGAGCCCAGGAGTTCCAGACCAGTCTTGGCAACATAGGGAGGCCCCCACCTCTACAAA ATATTTAAAAATTAGCCATGTGTAGTGGTGCATGCCTGCATTGCCAGCTACTCAGGAGGC TGAGTTGGGGGAGGATTGCTTAAGCCCAGGAGGTTAAGGCCGTAGTGTGCCTTGACTGTG CCACTGCACCCCAACCGGGGCGACAGAGCAAAACACGGTCTCAAAAAAAAAAAAAGGAAG AAAAGTAAAGAAACTCAGGGTACTGTGGGAGCACAGAGAAAATTTTCTGGGTCAAAGAAG ATTCTAGCCAGGCCATTCCCTGGAGGAATCCACAGGCTGGTCTAGCTGTCAGACCAAGAT ACAGACACAGCATAAGTGAAGAGTGACTTAGAATTTTCTTAGACAAGGTGAGAAATGGTG ATCCACACAACAGGTATCGCTTGTGCAAAGACCTGGGGGGCATGAAGGGGTGTGATGTGT TCCATAATTGGGTGGCTGGTGGTGGTCAGCTTGTTATAGTCGTGGTTAGCATTTACTGAC GGCTTACTAAAGCTGGGCCCACTGTTTAGTGCCAAACGTGCCTCATCTCAATTTCATCTT CCTGGCATCCCTGTGAAGAGAAACGCCTATCACGGCCATTTTACAGATGCAGAATCTGAG GCAGAGTTGTTAAGTCACTTATCCCCCGTCCCTCGGCTACAGGAGCAGGGAAGGGTTTGA GTCCCCCAGCACTGGGCACGCCACCTGTCAGAGGCTGCCAGGAGAGGTGGACAGGCAGTC TCATAGGAGCTTGAAGGCCCCCGTCAGCACCTCCGGCTCTCCCTTAGGCCAAGCTGCAGA CACATGCTGGGCACAGGCCTTCCACACAGCCTCACTGTGTACAGCCTGAAAGAGTGCCAG CCCACCCACACCCCTGAGATTGCCTTTCAGACGTGGGGTGGTGCAGAAGCGGGCATCAGA ATACCTCACAAATGCACAGTGGAGCTTTGCTAAGGATATAAGAGCCTCCTGTTAGGCTGT GGCAACTCACTCGCCTGGCTCCCAAAGCACGACCACTGTCAGAGAAAAAGGTTGAATGTT AAAAAGGATCCTCAGTCCCAAAGAGAGAGAGGCGAGGATGTAAAATGCAGCATTGTCCGT CACAGGGCAAAACTGGAAACAGTCCAAATGGCTGTCAGTGGATGGGTTAAATGAACTATG GTTCATCCATACAATCCAATACTATGTAGCTGCTCTGAAAAACGAGGTGAGGCCGGGCAC GGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCAGGGGGATCACTTGAGCCCAGGA GTTTTGAGACCAGCCTGGGCAACATAGCAAGATGCCGTCTCTTTTTTAAAAAATTATTTT TTAAATTAGGTGGGTCTGTAGCATATTGTTCTGCCGAAAACTCAAGATGTTGTATTGTAC TATGACCTATTTCTGTAAAAAATATTAGTTTTATGCAGAGAAAACTGGAGTAATTTCCAT TAAGCTTAGCTAACAGTGGTTATCTTTATAAGGGTGGGCTTGGGCAATTACAAGGTGAGT GCCGCAAGTTATATGTTGTTGAAGTATACATGAGTATAATCAAGGTTTTTGCAGAGGTTG TCCAATCTCTCTTTCTCTCTGTCTCTCTCTCTCTCTCATTCTCACTCTCTCTTTCTCTCT CTCTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGGGTGAT CTCGCTGACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGA ATAGCTGGGACTACAGACACGTGCCACCATGCCTGGCTAATTTTTTGTATTTTTATTAGA CACGGGGTTTCATCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCA CCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCGTGCTCAGCCTTTCTCTC TCTTTTTAAATAGAGACAGAGTCTCACTGTGTTGCCCAGGCTGGTCTTGAACTCCTGGCA TCAAGCAACCTTCCTGCCTCAGCCTCCCAAAGTGGTGGGATTACAGGCATGAGCCACCAC GCCCAGCCGGAGTTGCACAGTCTTAAAAAGCAATTTTTTAAATTGTCGTATGTTCGGAAG GGAGGGTCTTATTCAAAAAGACTTGGACGCAGAGCAGTGAGTATCCGGGGAAGGGAGTTG TCTGAGGTGGTGGCTTGGTCAGAACTGCATTTTGGTGAAATCCATTGCAGGGCCCAGCCG TGGTCCAGCCTGAAGCAGGCATTCATTCCAAGGTAGAGGAGCTCCTGGAGCTCCTGCCAG GAGCCAGACCCTGTTCTCAGTGCTGGGCACCCAGACAAAGTCCCTGCCCTTGTGGACATC CTGGCAATTCCATAGATGTCTGGGAAGACTGCAGAAGCCAGAGAGAAGGGCCTTTGAAGT GGAGAGGGGCGAGCTGACCCAGACAGCCTCACATGCAGGGCAGCAGGGTGGATGGGAGGT GGAGACTGAGGCTGGGAGGCTGGGGGAGGAGGCTGGGGCAGGACCCCCGGAGGAGAGGAC AGGCTGGACCAGGTGGAGCGCCGGGGAGGGAAAGGGGGTTGGTGGACAGACCCTTAGGAG GCTCAGCGTACATGCTCTGGAGCTGAAGGGCTGTGGCAGGAGGGCGAGGAGGGAGGCGGG GGCAGGAAACATCTGGCTGATGGGGGGGACAGTACGATCGCATTGAGATGAGGCCTGGGA GGAGGATGGGCTTGGAGGAGATGCCAGGGTCCATTTGGGACATAGTAGGAGTGAGAGGCT GGGGGGCACCTAGGGCAAGGTGTCCAGGAAGCCAGGGAACCCCGGATCTGAGGGCAGAGA GATGGTATCATGAGTGACGAGGCAGAGGTCATTGGCATGGATGAGACAGGTAACCCCAGG AAAGTGGAAAGAGAAAGCAGAGAGGCCCTGGACAGAGTCCCAGAGACCTGCCAGTCTGGA GCTGGGCTGAGGGGAGGCTTCGAGGAAGGAGACAGAGGTTGCTGGAGAGGTGGGCAGAGT GTCTGAGGCCTCGAGCAGGGGGCACATAGGTCCTTGAAGTGAGGGCCAAGGCTTTGCATT GGAATCATTCCCAGAGTGACTTGGGACATTATTCAGAGGCCCCCAGGGCTGCTGGGAAGG GACAGCAGGCCCACGCTCCAGGGGACCCGGGAACGAAGGGAAGACCCCAGGCTGTGATAA TAACAGCAACAGCCAGCGCTTACCAAGCACTTCCCCCGCCCCTGGTGCTGCGCCCAGCAC CCAAGCTCCCTTTCCAAGGTGAGGGACACCAAGACTTAGAAAATCAAAGTCACGACCAGG CACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGAGACTTGCTTG AGCCCAGGAGTTCAAGACCACCCTGGGCAACAGAGGAAGACCTCGTCTCTACAAAGCAAA CAAACAAACAAACAAAAAATGAGCCTGGCATGGTGGCACGTGCCTGTGGTCCCAGCTACT TGGGAGGCTGAGGTGGGAGGATCCCTTGAGCTTGGGAGGTTGAGGCTGCAGCAAGCTGTG ACTGCACCAGTGCACTCCAGCCTGGGCAACAGAGCGAGACACTGTCTCAAAAAAGAAAAG CAAAGCAAAGCCACTCACATGAGGTCTTGCTCCTGGGGACGGGCATGGCCAGGACTCCAA CCCCGGCAGCCTGTCCCAGAGCCCTGGAGCTAGCCCCAGTGCAGTCTCTCCACCACCCCG CACTTCCTCAGGCCACCTTCCTGCCACAGCCTTTTCCCCAAACCTGGTATCACCCCCTCT CCTCCCTCCCTAATCCCACCTCTCGGGCCTGGCCACTCCACCCCACCCCTTCCAGGACTC AGATTCAGACTCTGAGGGAGGAGCCGCTGGTGGAGAAGCAGACAGTGAGTATCTTCCTGG AGGGACAGGGAGCAGGGTTCTGGGGGGCGGGGGGATTTCAGGGCAGGGGTGTGGGTGATA CCTCCTCAACTCCATCAGGAGTGACATCCAAAGTATGTAGCAGTGGGTTGGGTACCAGTG CCAGAGCAGGCTCCTGGAGGCCGCTGGCTGGGCCGGGCCTTGTGCCTTTAGATGTGGGGA GGCCGGGAACCCCAGGGCTGGGGCCAGGGTGCCGGAGACATCCATGCCCCTGGCTGAATG CCCGTCCTGCCGCTGTCTCTCTTCTTTCCGGTCAGTGGACTTCCTGCGGAACTTATTCTC CCAGACGCTCAGCCTGGGCAGCCAGAAGGAGCGTCTGCTGGACGAGCTGACCTTGGAAGG GGTGGCCCGGTACATGCAGAGCGAACGCTGTGAGTCCCCTGTCAGGATTGGGCCACTTTG CCTGGCTCCTGGCCCCAAGTGACCTCCCATCCCCAGCCACTTGAACCATTTATTGAAACC TTTTCTTTATAAGTAGCAAGAAACCCAGCTGGAACTGGCTTAAGCCAAAAAGGAGTGTGT TGGCTCTAATCCAGCTTGAAGCACGGCTGGGTCCAGGTGCTTCCACTTTGTTAAAAATCA TAACTCTCTCTGATGCTGCTTTTCTTGTTTTGGGGTAAAGGTAACTCCTGGCAGCTGCAA ATGCAGGTTCCACTAGCCTAGGAGCTGCCACCGAGAGAGCACCTTTTCCCAGTAGTTCAA ACCAAACAGCAGAGATTGGCTCCCATTGGTCCCGGTTGAGTCAAATGCCTGCCCCCATGC CTCTGATTGGCCAGACCTGGGTCGCTTCTCCATTGCTGAGTGAATTACTGCACTCTGATT GACCAGGCCTGTTTCATAAAATGAGGATAATGATTATAGTATCTAACTCATAAGGTTATT GGCGGGGCTAAATAAATTAATATAGGACCAGGGGCAGTGGCTCATGTATGTAATCTCAGC ACTTTGGGAGGCCATCGTGGGAGGATCACTCAACGCCAGGCGTTCAAGACCAGCCTGGGC AACATAGTGAGACCCCCCCGCCATCTCTACAAGAAAAAAAAAAATAGTCAGATATGGGGG CGTTGCCTGTAGTCTCAGTTACTCAGGAGGCTGAGAAGGGAGGATTGTTTGAGCCCAGGA ATTGGAGGCTGCAGTGAGCTATGATGGCACCACTGCACTGCAGCCTGGGCAACACAGTGA GACTCTGACTCTAAAAAAAAATAAAGTAATAAAATTTAAAAGATAAATAAAAATGCAAAT GCTTAGAGCAGGGCCTGGAACATAGCGAGAGCTGTGGCAGGGTGTGCCGTGGTTATTACT ACAGGAGGCTTATTTCAGATGTGGTGGATAGGTGTCCACTTACTGAGTCAGCATGAAATT TATATTTCTTTTTCTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGA GTGCAGTGGCACAATCTCAGCTCACTGCAACCTCCACCTCCCGGGTTCCAGCAATTCTCC TGCCTCAGCCTCCCGAGTGGCTGGGATTACAGACGCACACCACCACGACTGGCTAATTTT TTGTATTTTAGTAGAGACAGGGTTTCACCATGTTGCCCAGGCTGGTCTTGAACACCTGAG CTCAGGCAATCCACCCTCCTCGGCCTCCCAAAGTGCTAGGATTAGAGGCATGAACCACCC GTCCCGGCCTGAAATTTATATTTCTTGCCACAAGTTGAGGTCACCAAAGTCTGAGAAACC AGGCCCTTGGCAGTCCTCAACTAGAACAATCGACCCTTTGTGGTTCCTGAGCAGCCTTTT GTTGAGGACATCTTCTCCTGTGTCCCTGTCCTCCAGCTGCCACTGTCTCCCTCCTCAGGC AGCCAGGCCTGCTGCCCTGAGCCTCCCTCTCCTGCGGCAGGCGAGCAGCTGTCTGCAGCC ATCTTTTAGCCTGGGCAGGCCCCAAAGACAACACAGGCAGTGGCTACAAAGCATTTGTTC CTTGTGTCCTCCTGCACCTGGATTCTGGGGTAATTGGCTCATGAGGGTGCCCAGGAGGAG ATAGTAATGAAAAATAACAATTAGTTGAGGCCGGGAGTGGTGGTTCAGGCCTATAATCCC ACCATTTTGGGAGGCTGAAAGCAGGAGGATCGCTTGAGGCCAGTAGGTCAAGACTAGCCT GGGCAATAAGCGAGACCCCCTCTCTGCAAAAATTTAAAGGTGAGGCTCCAACCCTCACCT CACTGCTCTAAAAATTTATTATTATTATTATTTTGAGACAGAGTCTCACTCTGTTACCCA GGCTGGAGTGCAGTGGCGCTATCATGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCG ATTCTCCTGCTTCAGCCTCCCGAGTAGCTGGGATTACAGGCGCGTGCCACCACGCCCGGC TAATTTTTGTACTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGCTGGTCTTGAAC TCCTGACCTCAGGTGATCTGCCCCCCTCGGCCTCCCAAAGTGCTGGGATTACAGGAGTGA GCCACCGGGCCCGGCCCTAAAAATTTCTTTTTAACCACTTAATTGAGGCTTCACTATTTG CCAGGCACTGGGCTCAGCACTTTACAAGTGCCCTATTATTTGATATTCACATTATACCTG TAAGATCATTATGGAAGTGATCTGAACAGAGGAGGAAAAGGAGGCACAAAAAGGTCACGA CTCAGTGTAGGGTCAAACAGTTGCCAAGTGGCAGAGCCAGGATTTGACCCCAGGTCCCCT GAATCCAGACCACATGTAGCCACCACTGGATTCAACCAGGCCTGGCCTGATGGCATCTCA GAGCTGAAGCTCAGGGCTGAAGCTGTGGCAGGCTTTGTGCTCTGTTCACCTTTGCTGTCC TCCCTTGGACAGGGCATCCCAGAGGCATCTGATCCACAGCATATCACACTTGTGCCTGTC TATCAGCTGATGGGCAGATGCCAGGGTACTATGGCCTGGTGGCTACTCACCAGCCACCAG CTAGCTATTTCTGCTCAGCCCAGGGTTCTTATCCTAAAGTGGCCTTTTCTCAAGTCCAAG TTGGTGTGATTTCCAACAGTGGATTCTCTTTTTTTTTTTTTTTTCCTTTTTTTGAGATGG AGTCTCGCTCTGTCACCCAGGCTAGAGTGCAATGGCATGATCTCGGCTCACTGCAACCTC CGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGAGATTACAGGC ACGTGCCACCACGCCTGGCTAATTTTGTATTTTCAGTAGAGATGAGGTTTTGCCATGTTG GCCAGGCTGGGCTCAAACTCTTGACCTCAGATGACCCGCCTGCCTCAGCCTCCCAAAGTT CTGGGATTACAGGCATGAGCCACTGCACCCAGCCCAACACTGGATTCTTTATCCGCTGGC TGGCTCTTCCGCAGTTGATTGTGTGACTTCTTCCCCTATCTGAGCCCCAGTTTTCTCATT TATAAAATGGGGATGTTAACACCATCCCCGTCTAGATGATTGGAAGGCCCGTCATGCATC TGAGATGCTTGCCCCAGGGCCTGGCATGGAGTAAACGATGTCAGGGGCTGTGATGGGTGG TGCTATCGTAGGGACTGAGCAAACGGTGTCATATGGTGCATAAGTTCCTCTCCTCCAGGT CGCAGAGTCATCTGTTTGGTGGGAGCTGGAATCTCCACATGTAAGTAACCCTTCTCCCCC AGCAGCTACCCCCAGGAACTGGGGAGTCCCTCCCAAGGGCTGGGGAGGAGCCCTATCTGA GCCCTGTCCTGGGAGGGTTAGTATGGTATAGACCAACTGCTCCCTGACCCCCCTTTCCTA GCCGCAGGCATCCCCGACTTTCGCTCTCCATCCACCGGCCTCTATGACAACCTAGAGAAG TACCATCTTCCCTACCCAGAGGCCATCTTTGAGATCAGCTATTTCAAGGTTTGTGCTCCC CCAGGAAGGGGCGTCTGTGAGGGGTGGGGATGGGGTCACCTGGCTCCAACCCTCACGCTA CCTGGGGCATCTGGCCCTCTGGCTGTCTCTCCTACAGAAACATCCGGAACCCTTCTTCGC CCTCGCCAAGGAACTCTATCCTGGGCAGTTCAAGGTGAGATCTTTGTTTTGCAGGGGGCG AAACAGGAAGGGTTGGGGGAGGGCACGCATGAGAAGCCCCGCCAAGGCCCTGCAGACAAA TATTATGTAGCCATTAAGTACATGGGTGCTGGGCCCAGACTGCCTCGGTTCAAGTCCTGG TTCCTCGTGTCTTCATCTTACGACCTTGAGCCTCCGATTTGCCTCCTGTGAAGTGAAGCT AATGGTACTGTCTGAAGAGGGCTGCTGCGAGGCTTAGCTGACTAATGATGCCGTTGAGAG CCCGGGACCCTGCAGCCGGGCTGCCTGGGTGTGAATCTCAGCTCTGCAGCTTACCCACCG TGTGACTTTGGCAACACAATCCCCTTCCCTGTCCTTCAGTTTCCTCATCTGTGATCTGGG GATAGCAGTGGTCTCTCCCCGACGCGGCTGCTGTGACGGTTCCCTGGGGGTAAAACAGTC ACAGTGCCTAGAACAGTTCCTGGCATGCGGCAGTGGCCTGTGGCTGTTCCCTGCAGTCGT CAGCAGTGCTGTCGCTCTTCCCTGCAGCCAACCATCTGTCACTACTTCATGCGCCTGCTG AAGGACAAGGGGCTACTCCTGCGCTGCTACACGCAGGTAGGCGGATGCGAGCATCCTGGG AGGAGGATGGGCGGGTGGAACGGGCATGGTGTCCTCAGCAGAGGAGCAGAGCTGCGTGCC CAAGAGCTCAGGCGGGGACTCCAGCAATGCGGGGCCAGGGCTTGGCCTACTGCCTCCTTG CTGCATGACCTGCCGTGAGTCACGTCTTCTCTGCCTCAGTTTCCCCTTCCGTCAAACAGG GGCCAGAAAAGGTTTGCCCTCTCAGGTCTGCCCTCTCAGGTCTGCAGTGCGGTGGCAGTG ACCTCCTCTCAGGGCCATCCCATGTGTGATGTGGAAGGAGCCTATGGCTGAAGGGACTCT GTGTGCACTATAGGCACCCCAGATTTCACATTGGTTATGAGCGAGTTTCCAAAGTGACTT CATCTAACAAAATCCATACACTATGACACGTGTCCAACAAGTAGATGTTGTGCCTTAAGG AAGGGGCACCTTTTTATAGTTTTTTGTGCTTTGCCCAATTATAAACATGTCTCGTACACG TCAGGTGCTTAGCCAAGGGCCTCTCCCTGGGGCATTCAAGCAAGGATGGCTCACATTGTT GGCTTCTGGTTTGGAGAGTCTCACACCCCTAACAGTAAAAAAATCTTGATGGGCTGGGCA CAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAAGCGAGAGATAGCTCGAGC CCAGGCGTTTGGGACCCGCCTGGGCAACATAGGGAGACCCTGTCTCTACAAGAAATACAA AAATTAGCTGGGCAGGGTGGCGTGTGCCTGTAGCCCCAGCTACTCAGGAGGCTGAGGTAG GGGGATTGCTTGAGTTCAGGAAGTCAAGACTGCAGTGAGCTATGATGGTGCCACTGTACT GTAGCCTGGGAGACCTGGTTTCAAAGAAACAAAAAACAAATCAAAACAACAACAAAATGT TGCTGCCTCTACCTGTTTTATGAATATGTATAGAAATGACATGATGCACTACAACAGTAT TAATTCAAGCTCTAGATCACACCTCAGAACCCCGAATTATAAAACAGGTGGCCGGGCGCG GTGGCTCACGCCTGTAATCCCAGCACTTTGGGACACCGAGGTGGGCAGATCACGAGGTCA GGAGTTCAAGACCAGCCTGTCCAACATCATGAAATCTGGTCTCTACTAAAAATACAAAAA TTAGCCAGGTGTGGTGGTGCCTGTAACCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATC GCTTGAACCTGGGAGGCAGAGGTTGTAGTGAGTCAAGATTGTGCCACTGCACTCCAGCCT GGGTGACAGAGCAAGACTCCATCTCAATTTAAAAAAACAAACAAACAAACAAAAAAGAGT GGTAACATTGAAAATAAATAAGTGTTCTAGTGTTTTCTCCCTGTACCTGCAGTTTGGCAC CTGCAGCCCCAAAAGCTACCGCCAGGGGGAGGAACAACTGGCTTTAAGTTCAGATTTCTC AGGTGGGCGAGGTGTTCCCACCTGGGGCTGGTAGGAGGCAGAGGGCAGCGGAGGCCTCCT TCTTCCAAGAGGAGGAGTCCTGTGATCCCCACACTTTGGGAGGCCAAAGTGGGAGATCGC TTGAGCCCATGAGTTCAAGACCAGCCTGGGCAACATAGGGAGACTCCGGGCTCAGAATAA ACCTTCTGCCCAGAGAGTCACCATTATTCCAGGACGTGGCTCAGATATGATAACAGCTTG CTTGAAGCCAAGTGCTTTTTGTGGTTGATGTCATGACACTCACCCCAAGACCCCGCTGGC CCTTGTTTGTCAGCTTCTGTCAAAGTAAATGTTCACTGAGTTGATTCCCTACAGCAGGGA GGGAGATGATGGACAAGATGGAGACACCATATACTGAGCATATAAGATGGTCATGGGTCC CTGGAACACAGTTAAGCTGGAAGGGGAGTCAGAAACGGTGTATGTGTTCGGGAAAGGGGG TGCTGTTGTAAACCCCATCTCTACGAAAAATACAAAAATTAGCCAGGCGTGGTGGCACAT GCCTGTAGTCCTAGTTACTCAGGAGGCTGAGGCATGAGAGTTGCTTGAACCTGGGAGGTG GAGGTTGCCCTGAGCTGAGATTGCCCCACTGCACTCCAGCCTGGGTGACAGAGAGAGACT CCGTCTCAAAAAAAGAAAAAAAATGACACATCACATACAAACTATTATATAAAGGCCAGG CGCGGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCCAAAGTCAACGTCAGGAGTT TAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCT GGGTGTGGTGGTGCGTGCCTGTAATCCCAGCTACTCAGGATGCTGAGGCAGGAGAATCAC TTAAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTCCGCCATTGCACTCCAACCTGG GCAACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTAGT GCACACCTGTAGTCCCAGCTACTTGGGAGCTTGAGAGAGGAGGATTGCTTGAGCCCAGGA TTTCAAGGCTACAGTGAGCTATGATCAAGCTACTGTACTCCAGCCTGGACCAGTAGAGCA AAATCCTGTCAAAAGAAAAAAAAAAAAAAACCATGTTGTCAAAGAATAACAGAACGCAGA GGTATTTCGGTGGTTCTTTTCCACGCTGTTCAGTTATTTGCTTACTGTTCAGTTATTTGC AAATTGCTCACTCACATGTGAGGGAGTCAGTGGGTAGACTGAGTCAAGTACCAAAGGCAA AACCAAGATTTAGAATAGTGGGCAAGGGAGGAAAGTTACAGGGCGTGTGGGAACAGTGAC AGTGACTCTTGTCTGTAGGCTTTGGAGATAAGGTGGTTGCTGGTAGGGAGCCCAGAAGGC AGTTAGAGCATTCTTTCTGCCCTTGAAGGGAAACAAACCCTTCCCGTTGTTTCTGGAGTC CCTGGGAAACGCTGTCAGTTTGGCCCTGGGCCACACATGCGAGCCATCTCTGCGTAACCT CTGCCAGTGTCCTCTGTCAGCACCTGTTTTAGCGGCATTCCTCACAGGCAAACAACAGCT GCTCCAAAGGGGGTGGTTGTTTTAAGAAAAATGAGCGCGCACAAATGTCTGTGCAGAAAA GAACATTCCCACCTGTTTAATATGGAAAGTCTCACTGTCTTAAAAGAAAACAGTGGCCGG GCGCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACGA GGTCAGGAGATCGAGACCATCCTGACCAACATGGTGAAACCCCGTCTCTACTAAAAATAC AAAAATTAGCTAGGCATGGTGGCGCGTGCCTGTGTTCCCAGCTACCTGGAAGGCTGAGGC AGGAGAATCACTTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCAAGATTGCGCCACTGCA CTCCAGCCTGGCAACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAATAGCCACGCA TGGTGGCGGGTGCCTGTAATCTCAGCTACTTGAGAGGCGGAGGCAGGGAGAATTGCTTGA ACTCAGGAGGCAGTGGTTGCAGTGAGCCGAGATAGCGCCATTGTACTCCAGCCTGGGCAA CAAGAGTGAAACTCCATCTGAAAAAAAAAAAAAAGAAAAGAAAAGAAAAGAAAACAGTGG CTGGGCATGGTGTCTCACGCCTGTAATCCCAACGCTTTGGGAGGCTGAAGTGGGAGGATC ACTTGAGCCCAGGAGTTCAAGACCAGCCCGGGCAAATAGGGAGACCACCCCACCCCCCAT CTCTACAAAAATAATTAAAAAGATAAAAAATTAGCCGGGCATGGTGGCATTTGCCTGTAG TCCCAGCTACTCAGTGGGCTGAGGTGGGAGGATGGCTTGAGCCCAGGAGGTGAAGGCTAC AGTGAGCTGTGATCAGACCACTACACTCCAGCCTGAGTGACAGAGCAAGACCCTGCCTCC AAAAAAAGAAAAGAACACAGGTGAATATGCCATCTATGAAACAGGCCATAGTAAGAAAGG ACCCTGGCTACTAAAGGGGAAGATAGTGATTAAAGCCAAGGAAGGGCCAGGCATGATGAC TCACACTGTAATCCCAGCACATTGGGAGGCTGAGGCAGAAGGCTCGCTGACCAGCCTGGG CAACATAGTGAGACCCCATCTCTACAGAAAATTTTAAAAATCAGCCAGATGTGGAGGCTG AGGTGGGAGGATTGCTTGAGCCCAGGAGTTGGAGGCTGCAGTGAGCTATGATTGTACCAC TGCACTATAGCCTGGGCGACAGAGTGAGACCTTGTCTCAAATACATAAAAAAACATGGCT AGGCACAGTGGCTCATGTCTATAATCCCAGCACTTTGGGAGGCCGAGGCAAGCAAATCAC GAGGTCCAGAGTTCGAGACCAGCCTAGCCAACATGGTGAAACCCCATCTCTACTAAAAAT ACAAAAATTAGCCAGTCATGGTGGTGCGTGCCTGTAATCCCAGCTACTTGGGAGACTGAG GCAGGAAAATCTCTTGAACCTGGGAGTCAGAGGTTGCAGTGAGCCGAGATTGTGCCACTG CACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAACAAACAAACAAACAAACA AACAAACCACACCTAGTAAGCCCTCCTGATTCATTTATGTTAATGCTTGCCTAGAGCTGC CACATGCAGCTGTGCAGGGTGCGCACTGCACAAGGATGCCACATCTGAGGGGGCTCCATT AATAACAGAGACATTGTAAATGTATGTTAATTTCAGCAATTAATGACAGGTGGAAATAAA GCATCTGGCTCTAATAAAACAACATTTTTTTTCTGAAAAATGAAAGCAAATGGCCTGAAT TTGCAGAATAAAAGCCACACAGGCTGTGGAGTGGCTGTGGGCCTGGCCTCATAGATATTT AGGTTTGGGCCCCTTTTTTTTTTTTTTTTTTTTTAATTTTTTGTAGAGACAAGCGTCTTG ATATGTTGCTCAGGCAGGTCTTGAACTCCTGGCCTCAAGTGATCCTCCCACCTCAGCCTC CCAAAGTGCTGGGATTATAGGCGTGAGCCGCCATGCCCAGCCTGGCCCCTGCCTTTAAGC AGCCTTGACTGTCACCCTTTAAGTGGCACCATTGGGATGAACAGAAGAGTCTTCAGATAA ACCCTGCCACTTGCTTCTCCTCCCTCCCTTCTCCACCTGTCCCCACCACCTCACTGCTCC TCGTGGCCCTCAACTCCCTACTGTGCCTTCTGGCCTACAAGGGGTGGCTCACTCCTCACC CCTCTTCCCTCCATCTCTCCCTCTAGAACATAGATACCCTGGAGCGAATAGCCGGGCTGG AACAGGAGGACTTGGTGGAGGCGCACGGCACCTTCTACACATCACACTGCGTCAGCGCCA GCTGCCGGCACGAATACCCGCTAAGCTGGATGAAAGGTGAGGCTGGAGGGCATCCTGAGG GCAGGCCTCCTCTCAGCACCAGGAGCAGTGTCTCCATGCAGTGGGCACCCATTCTGTCCT GCTCAATTCTTTGGGGTTTTTTTGTTTTGTTTGTTTGTTTTTGAGACAGAGTCTCACTCT GTCGCCCACGCGGGGAGTTCAGTGGGTGATCATGGCTCACTGCAGCCCAACTGCCTGATT TCCTGTCTTTGGCTGTTTTTAATATATGATAGTAGGCCAGGAGCAGTGGCTCACACCTGT AATCCTAGCACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCAGGAGTTCAAGACC AGCCTGGCTAACATGGTGAAACCCCGTTTCTACTAGAAATACAAAAAAAAAAAAATTAGC CTGGTGTGGTGGCATGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCG CTTGAACCTGGGAGGCGGAGGCTGCAGTGAGCTGAGTTCGCACCATTGCACTCCAGCTTG GGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAACAAGAAGTCACTT ATTCCACTCATGGAAAGCCATTTCTGACATTCTTTATGCTGATTTAACAAAGCCTCTGGT GTCCCTGTGAGATAAGGACAGCTGCAGCATTTGCAGAAGGGCCTCTGGAGTGTGGCTGTT CTGATAAAATGCCAGCTGAGTGCCCCTGGGCTGAGGATTCCTGAATAGCCCAACTGCAAG CAGCTGGGGGCAGTGTACAATTCACATTACCCCCATTATGTGTCATTGACAGCAGCGTCA CAGGCAGCACCCACGGTGTCATGCTGTCCATGCAGAAATATTTTAAAGAAAATTACCGAC TACTGACATTGAAACAATGCTTTATAAATGTGTGCTGAATGAATGAATGGACAGTTGAGC AAATGACTTAGAATTCAGTGGGTTGCAAGTGACAGAAATGCTTTCTTTCTTTCTTTTTTT TTTTTTTGAGATGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCAATCTCGG CTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCCTGCCTCGGCCTCCCAAGTA GCTGGGATTACAGGCACGTGCTACAACCCCTGGCTAATTTTTATATTTTTAGTAGAGACG GGGTTTCACCACGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAACGATCCACTCGCC TCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCGGCCAGAAATGCTT TCAAGCTTCCTAAATCAATAAGAAATAAGGCCAGGCACAGTGGCTCATGCCTGTAATCCC AACACTTTTGGACGTCGAGGTGGGTGGATCACTTGAGCCCAGGAGTTTGAGAACAGCCTG GGCAACATAGGGAGATCCCATCTCTAAAAAAAATAAAATGTAGCCAGGTGCGATGGTGGA TGCCTGTGAGCCCAGCTACTCGGGAGGCTAAGGCAGGAGGATCACTTGAGCCTGGGAAGT CGGTGGTGCAGTAAGCTATGATCACACCACTGCACTCAACCATGATTGCACCACCACACT CCAGCCTGGGCAACAGAGTGAGAACCTGTCTCAAAAAAACAAACAAACCAATAAGGCCGG GCGCAGTGGCTCACACCTGTAATTGCAGCTCTTTGAGAAGCCAAAGTGGGCAGATTTGCT TGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATGGCGAAACCCTGTCTCTACAAAAAA TACAAAATTTAGCCGGGCGTGCTGGCATGCACCTGTAATCCCAGCTACTCAGGAGGCTGA GGCAGGAGGATCACTTGAAGCTGGGAGGTTGAGGCTACAGTAAGCCATGATCGTGCCACT GCATTCCAGCCCGGGCAACAGAGTGAGACCTTATCTCAAAAAAAAAAAGAAAGAAAAAAA CAAAAAAAATGCAACAACAAGAAGAGAGGTCTTTTCTGAGCAGAGTGGACACCTCAGGAG ACACCCATCACACTCCAAGTGATGGAGGTGTGTTCATGTTAACAGTGGAAGAGGGGTGGG GGTGCTGCACCTCCAGACTCCGGCCCAGATCCTCTTACTGCCTTCTCTTTCTTCCCCTTC CCCATACCCAGAGAAGATCTTCTCTGAGGTGACGCCCAAGTGTGAAGACTGTCAGAGCCT GGTGAAGCCTGGTGAGCCTCTGGCCAGGGACCTGCCCAGGTGGATTTGGGTGGGGGTCCC CTCCTCCCCCTGACCCCCTCCCAAAGGCCACACCCGCACACATCTGGCCACCTCTGTCTC TCTGAACAGTGCCCCAGATCCATCCTGGGGAGAATGGGGTCTGTGCCCCTGGCCGGTCCC CACTGCTCCCAACTCCCACTGTGGCCTCCGGGTCTGCCATTGCTCCCACCTGTCCTCTCT GCCTCCCCATGTCACTGTCTCTGTCCGTCCATCTGTCTCCACCTCAGATATCGTCTTTTT TGGTGAGAGCCTCCCAGCGCGTTTCTTCTCCTGTATGCAGTCAGTAAGTGGCCCCCCAGC CTCCCCGCATCCCCAACCGCCGCCTCCACCTGTGCTGGGCCCCATGGGGGCAGCCTGGGC CCTGCCTCAGGAAAGGTCACCTCCCCAGCTATGGGGGGCGGCAGGGAGGTTTGCTGCTGG GGGCGGGGGAGGGAGCGGTGGCGCAGCCTGGGCGGAGGCTCCCAAGCTCACGCCCCTCCC CGCAGGACTTCCTGAAGGTGGACCTCCTCCTGGTCATGGGTACCTCCTTGCAGGTGCAGC CCTTTGCCTCCCTCATCAGCAAGTAGGTTGGGGGCTGTGGCTGGGAGGACGGCTGGGCAC CCAGGGCCAGGACAGACCCTGACCCCTTAGCTCCCCCTCCCCACAGGGCACCCCTCTCCA CCCCTCGCCTGCTCATCAACAAGGAGAAAGCTGGCCAGGTAAGAGCCCTTCTTCAAGCCC CCGTCGTCACAGGCTCCCCCTTCCCTCTCACCCTTTTCCTCAGAGGGAACCCCCACTGTG GAACCCCAGCACTTTGCATTCCTCAGCTCAGAACCTGGGGCTCTAGAATCCAGAGGGGTC GGGTTCCAGGCCTCTGGGACATTCACTGCCCTTTTGAGCAAGTGATAGAATTCCAACTCA AACCAGCTGAAGCCAGATAGGAAGGCCGGGCTTCCAGGGACTGAGGAGGTGGGAGGGGGT GCAGGGGTCAGGAGAGACAGTGCGGGGGGCGGGGTTGGGTCCACGCTCTGGGTCTCTCAG GTCTGTTTTTCCTGGGCAGCCTCACTCTAGGGCAGGTGCTCCCTCCTAGGTGTTCCCCTC AGGGGAAGTAGGCAGGGTCACCGGGCAAGCAGCGCACGCTGTGGGCAGACACTGTCCCAA GTCTTAGCCTGCGTGAACTCACTGGCGCCACAACCCCATCGCGGTTTTGTGATCACCCCT ATTCTACAGGAAACTAAGACACAGAGAGGACAAGTCACTTGACCAAAGTCACTGAGCTGG CTGGGCGCAATGGCTCACGCCTGTAATTCCAGCACTTTGGGAGGCCGAGGCGGGTGGATC ACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAA TAATACAAAATTAGCCGGGCATGGTGCTGGGCACCTGTCATCCAGGCTACTCGGGAGGTT GAGGCGGGAGAATCACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATCACATCA TTGCACTCCAGCCTGGGCAACAAGAGTGAAACTTTGTCTCAAAAAAAACCAAAAAAACAA CAACAAAAAAAAAACAAAGTCACAGAGCTAGGATACAAACCCAGGCCACCTGGCTCCAGG GTCTGTGCTCTTAGCTCTCCCTTCCCTGCTCCTGCCCCTGACCCACCCCCTCCCTGACAG TCGGACCCTTTCCTGGGGATGATTATGGGCCTCGGAGGAGGCATGGACTTTGACTCCAAG AAGGCCTACAGGTGAGGCCCCGCCGGGGGTTGGGGCAGCCTGGAAGGGACAGGGTGAGGT GGGAGCGGGGGCACGAAGGCAGATGAGAGGAGCAGGCAGGGGCGAGCCCGCCTGGGAACT CTGATCTCCTGCTGCACCGCAGGGACGTGGCCTGGCTGGGTGAATGCGACCAGGGCTGCC TGGCCCTTGCTGAGCTCCTTGGATGGAAGGTGAGGAGCTGAGCAACCCCAGCCTGTCCTG AGCCCCATCCCTGGACCCTCTCCCCACCCCATGGGTCCTCTGACCCCATGATGCACAGTG ACCTTTGACTTCTGTGACCTTTGCTCCTGCAGAAGGAGCTGGAGGACCTTGTCCGGAGGG AGCACGCCAGCATAGATGCCCAGTCGGGGGCGGGGGTCCCCAACCCCAGCACTTCAGCTT CCCCCAAGAAGTCCCCGCCACCTGCCAAGGACGAGGCCAGGACAACAGAGAGGGAGAAAC CCCAGTGACAGCTGCATCTCCCAGGCGGGATGCCGAGCTCCTCAGGGACAGCTGAGCCCC AACCGGGCCTGGCCCCCTCTTAACCAGCAGTTCTTGTCTGGGGAGCTCAGAACATCCCCC AATCTCTTACAGCTCCCTCCCCAAAACTGGGGTCCCAGCAACCCTGGCCCCCAACCCCAG CAAATCTCTAACACCTCCTAGAGGCCAAGGCTTAAACAGGCATCTCTACCAGCCCCACTG TCTCTAACCACTCCTGGGCTAAGGAGTAACCTCCCTCATCTCTAACTGCCCCCACGGGGC CAGGGCTACCCCAGAACTTTTAACTCTTCCAGGACAGGGAGCTTCGGGCCCCCACTCTGT CTCCTGCCCCCGGGGGCCTGTGGCTAAGTAAACCATACCTAACCTACCCCAGTGTGGGTG TGGGCCTCTGAATATAACCCACACCCAGCGTAGGGGGAGTCTGAGCCGGGAGGGCTCCCG AGTCTCTGCCTTCAGCTCCCAAAGTGGGTGGTGGGCCCCCTTCACGTGGGACCCACTTCC CATGCTGGATGGGCAGAAGACATTGCTTATTGGAGACAAATTAAAAACAAAAACAACTAA CAATCCGG OMIM ID 604480