| Entrez gene ID | | 22821 |
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| Official gene symbol | | RASA3 |
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| Full name | | RAS p21 protein activator 3 |
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| Aliases | | ,GAP1IP4BP,GAPIII,MGC46517,MGC47588, |
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| Gene summary | | The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq] |
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| Location | | Chromosome: 13 Locus: 13q34 |
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| Gene position | | 114898095 - 114747194 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 150902 bp |
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| Gene sequence |
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| OMIM ID | | 605182 |
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