| Entrez gene ID | | 22601 |
| Official gene symbol | | Yap1 |
| Full name | | yes-associated protein 1 |
| Aliases | | AI325207,Yap65,Yki,Yorkie |
| Gene summary | | This gene encodes a protein which binds to the SH3 domain of the Yes proto-oncogene product, a tyrosine kinase. This protein contains a WW domain, consisting of four conserved aromatic amino acids including two tryptophan residues. This conserved WW domain is found in various structural, regulatory and signaling molecules in various species, and may play a role in protein-protein interaction. Following cellular damage, phosphorylation of this encoded protein may suppress apoptosis. This protein may be involved in malignant transformation in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
| Location | | Chromosome: 9 Locus: 9 A1 |
| Gene position | | 8004596 - 7931999 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 72598 bp |
| Gene sequence |
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