| Entrez gene ID | | 2052 |
| Official gene symbol | | EPHX1 |
| Full name | | epoxide hydrolase 1, microsomal (xenobiotic) |
| Aliases | | ,EPHX,EPOX,MEH, |
| Gene summary | | Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Location | | Chromosome: 1 Locus: 1q42.1 |
| Gene position | | 225997797 - 226033264 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 35468 bp |
| Gene sequence |
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| OMIM ID | | 132810 |
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