| Entrez gene ID | | 204801 |
| Official gene symbol | | NLRP11 |
| Full name | | NLR family, pyrin domain containing 11 |
| Aliases | | ,CLR19.6,FLJ26273,NALP11,NOD17,PAN10,PYPAF6,PYPAF7, |
| Gene summary | | NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM] |
| Location | | Chromosome: 19 Locus: 19q13.42-q13.43 |
| Gene position | | 56348128 - 56296763 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 51366 bp |
| Gene sequence |
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| OMIM ID | | 609664 |
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