| Entrez gene ID | | 199713 |
| Official gene symbol | | NLRP7 |
| Full name | | NLR family, pyrin domain containing 7 |
| Aliases | | ,CLR19.4,FLJ94610,HYDM,MGC126470,MGC126471,NALP7,NOD12,PAN7,PYPAF3, |
| Gene summary | | This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] |
| Location | | Chromosome: 19 Locus: 19q13.42 |
| Gene position | | 55458873 - 55434877 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 23997 bp |
| Gene sequence |
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| OMIM ID | | 609661 |
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