| Entrez gene ID | | 1951 |
| Official gene symbol | | CELSR3 |
| Full name | | cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) |
| Aliases | | ,CDHF11,EGFL1,FMI1,HFMI1,MEGF2,RESDA1, |
| Gene summary | | The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq] |
| Location | | Chromosome: 3 Locus: 3p24.1-p21.2 |
| Gene position | | 48700348 - 48673896 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 26453 bp |
| Gene sequence |
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| OMIM ID | | 604264 |
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