Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Abcb1a (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID18671
Official gene symbolAbcb1a
Full nameATP-binding cassette, sub-family B (MDR/TAP), member 1A
AliasesAbcb4,Evi32,Mdr1a,Mdr3,P-gp,Pgp,Pgy-3,Pgy3,mdr-3
Gene summaryThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a p-glycoprotein which actively transports a variety of hydrophobic amphipathic drugs and plays a major role in the blood-brain barrier permeability of certain drugs. [provided by RefSeq]
LocationChromosome: 5   Locus: 5 A1|5 1.0 cM
Gene position8660092 - 8748570  Map Viewer
Gene orientationplus
Gene size88479 bp
Gene sequence