| Entrez gene ID | | 18671 |
| Official gene symbol | | Abcb1a |
| Full name | | ATP-binding cassette, sub-family B (MDR/TAP), member 1A |
| Aliases | | Abcb4,Evi32,Mdr1a,Mdr3,P-gp,Pgp,Pgy-3,Pgy3,mdr-3 |
| Gene summary | | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a p-glycoprotein which actively transports a variety of hydrophobic amphipathic drugs and plays a major role in the blood-brain barrier permeability of certain drugs. [provided by RefSeq] |
| Location | | Chromosome: 5 Locus: 5 A1|5 1.0 cM |
| Gene position | | 8660092 - 8748570 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 88479 bp |
| Gene sequence |
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