| Entrez gene ID | | 1646 |
| Official gene symbol | | AKR1C2 |
| Full name | | aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) |
| Aliases | | ,AKR1C-pseudo,BABP,DD,DD2,DDH2,FLJ53800,HAKRD,HBAB,MCDR2, |
| Gene summary | | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq] |
| Location | | Chromosome: 10 Locus: 10p15-p14 |
| Gene position | | 5060207 - 5031965 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 28243 bp |
| Gene sequence |
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| OMIM ID | | 600450 |
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