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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NKX2-6 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 137814 Official gene symbol NKX2-6 Full name NK2 transcription factor related, locus 6 (Drosophila) Aliases ,CSX2,NKX2F,NKX4-2, Gene summary Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is essential for development of the heart-like dorsal vessel. NKX2-6 is a vertebrate homolog of 'tinman' (Newman and Krieg, 1998 [PubMed 9621430]).[supplied by OMIM] Location Chromosome: 8   Locus: 8p21.2 Gene position 23563922 - 23559964  Map Viewer Gene orientation minus Gene size 3959 bp Gene sequence >NKX2-6:complement(11418110..11422068):Length=3959 GACAGAAAGCTGGATGGTTCGGAGCCTCCTGGGGGTCCCTGTGAGGCAGTCTTGGAGATG GACGCGGAACGGATGGGGGAGCCACGTGAGTAAGCGCTCAGGTCTTGCCTCCTACGGGGG GAATGTGGGGGCGGGGGCGTGATCCATGGGTGCATGGGGAAAATACGCCTCCTATCTCCT GGGTTCGAGACTCTCTCCATTTTCTCTCGAGGAGTCCAAAAAAAGGCCTCTCGAATCCCA TTCCCATCCTCTCCTGACACCCAGTGTGCTTCACACACCCCTAACGAAAGTAAGGCCCTG AATCTCAAGGATTCACTTTTCCCAAATCCGCTCCTCTGATTCCCACAAACGCATCGCTCA CACTCGCAGCCACAGTGCCCAGAACCTCCACCTTCTCATCTCCACAGCGAAACCCTCCGC AGTGTCTTAGCCGTGCCAGTCACCACCGCCCTTCCCTACCATCACCTGGTGTCTCTCCAC CCCCAAACCGTTTGCAAAAGCGTGTGGCCATCAAAGCAGTGGAACCCTCGTGGCGCTGAG GTCACTCCTAACTGGGCCCTTTCTTGCTGGTCTGGTCGGGGGACCCCCCCATTCCTCCTC ATGGATTTTTCTTCTGGAAGACGAAAGTTGGGGACCGGGTGGCGATTGAGTCTCCCGAAG TGGAAGGCCCCGTTGGCGCAGGATTCTCCGCGTCAGGGAGAACGTTAAAGGTTGCCAGGG TTTTCTCTGCCCTGGGACACGGTTCTGGCCGAGTCCTGTCGCAGGTATCCAAAGGCGCAA CCGTGCGCGCCGGGCTGCGAGGCCCACGCACCTGTGTCCAGCCCGCTGGAAGGGAAGGGG CTGGCGGGGAGTTGTGTTGCGTCGATCCGGGAGTTGTGTTGTGTCGATCCGGAGGCTTCA GCTGGAGAGGCCCGATATTCCAAGGGATGAAAACGCCACCTTTTTCTCTCCAAACCTCAG CACCTCACTCGGCATTCTCAACGCAGGGGCCCTGAGTAGCGCCCGCCAGGGCAGGCCTCC TCTGCCAGACTGTGCCATGGCGCCTCCATTCAAGGCGCGAACGAAAGAAATAAACCAAGG GGCTAGATCGGAGTTATTTACCGGCCTGCAGGCCGGCTACTCACTAACTCCAGAAGCCTA AGAACATTACCTGCTGTGTCCGCGAAGAAGCTGGTAGGTTTTCTGCAGCGGATTCTAAAC TCCCTCGGCGCTGCTCAGCCAACTCGGCGATCACTTCGGCTCCGCTGAGCTGACAAAGGA TCACGTTCCTTCGACCACCACAGTCGCCTCGCAGCCGATGGTATTTGCGGCGCCTTCCTT CTCCCACTGGAAACCAAATCCTGGGAGCGTCTCTTCTGCGGCAGCAGTGGACGCCGCCGA GGAGGGACCCGAGGCCGGACCCGAGGCCGGCTCCAGGAACTGAGCCCAAGGCCGCGGTAG CGATCCGGACAGGGAAGACACCTTCGGTGGGCTTCATGCCTTCCTCCATCGCAGCTAACC ACCTTGCCCTCAAGAACTCCAGGATTGTGAACAGAAGGGCGCAGGGTGCTGGCCCACCCT GCGGTGCTGTGCAGCCCCAGGGCCTGCATGATCTGTGACTTTGAAATGGGGTCCTCCTTG CTCTGCAGCCTGGCTGAAGGTCAGTTGTTACCTTTCGATGCGCTAAGAAAACAAACCCTC CTCAGAATTTTTCCTCTTTGCAAGTGGAGATGGCCTCAGTTTATCTGAGCACAGACGTCT CTGAAGGAAGTTGTTCTGTCCTCAAACTTTACATACCAAACAGCTCCATCCCCCTCCAGG AGATTGTGCCAGTGCCTTGGGTATTAGGAGTCTGGTTCCAATCGCACTGGCTCATTTAGA GTCCTGTCCCGTCTTGCCATGAACTTGCACCCCTTCCATGCTCCTGATTTTCTCCTGGCG TGAGATCCCATGAAAACTCAGCATTTCCCTTCTATCCACCCTTGGGGTAAAACGGGGTTT AAGCCCAGACAGGAGAGAAGTGAGAAGGGAGGAAAACGCTGCATCTTGGTGGGCACAGTC TCAGCTGTAGGGGTCGCCCTGGGTGAAAGGAAGACTTCAGGGTGAAGCCCACACCACCTG CTTGCCAGAAAGACCCCAAAGGAGGGAGAGGCTACTTTTTAAGAAGCCAAATGTGGACCT CAACTTTATGTATCTCTCAAAGAGAACCTCAGTTTCTGAGCCAAAAGTCAGGAGCCAATA AATATTTTGTTTTCATCATATATTGTTAATTTGGATTACAAAGCATCACATCCAAGAAAG CTGGGATGCATCCCTGGTGTTGGTGGAGCGCTGCGTCAAAAAGACAAGAGTGTGCACAAA AGTTGGGTGAAGGTAGGAGACACTCAAGGCTCCCGCTCCTGGACTTACAGCCAAGTTCCC TGCAGTGCGCTTGGGGCTGCGAAGGAAAATGAGGCAGACAGGAGCCTCCTGAGAGCCTGT CACCGAGTTTGCGCCTTCTTGACACCCGGGCTTCTCTCTGTTTTTCCTTCCTTTCCTTCT TCTTCTTCTCCTCCTCCTCTTCCTCCTCCTCTTCCTCTTCCTCTTTCTTCTCCTTCTTTC TCTACTTCCAAGGAGGGTCCAAAGTCTCCTCAATCTGATAGACACCTCCACTCACACTTG TTCCTCACAGCGAAGGTTTACCATGCACACACAGTTTTTTTTTTGTTTGTTTGTTTTTTG TTTGTTTGTTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACG ATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCC CGAGTAGCTGGGACTACAGGCACATGCCACCTCGCCCGGCTAATTTTTTGTATTTTTAGT AGAGACGGGGTTTCATCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGC CCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCGCCCGGCCCATGC ACACACATTCTAAGAAGCAAATGGAGCTGCCTTAACTCTTTATCTAGAGTCTACCTTTAG GAAAAGGACGCACACACGAGGGACCATAGGTTGTCACAATTTATGTTCCAGCAGTAACAT ATAAAGGTGACAGAGCTTGGAGGGAAAAAACATGGAGACAGTCCTGGGACAGGGTTCGTC CTGGGACAGGGTTCGGGGGCAGTAGGAGGGAGGAGGAGCCTGCGCAGAGTGAAGGCTGCC AGGGAGAGGAAAGTCTTGAAAACTAAGTAGGAACCGCTCAGGTGAGCCTTAGGCTGGGCG CTGATGTGTCCCTTCCTGTGCTTTTAGAGCCCGGCCTGAACGCGGCCTCGCCCCTCGGCG GCGGGACCAGGGTGCCAGAGCGCGGCGTTGGCAACAGCGGCGACAGCGTGCGGGGTGGCC GCTCGGAGCAGCCCAAGGCGCGGCAACGACGGAAGCCGCGCGTGCTCTTTTCGCAGGCGC AGGTGCTGGCCCTGGAGCGGCGCTTCAAGCAGCAGCGGTACCTGTCAGCGCCCGAGCGCG AGCACCTGGCCAGCGCGCTGCAGCTCACGTCCACGCAGGTCAAGATCTGGTTCCAGAACC GACGCTACAAATGCAAGAGACAGCGCCAGGACAAGTCGCTGGAACTGGCTGGCCACCCTC TAACGCCGCGCCGAGTAGCTGTGCCCGTCCTGGTGCGCGATGGCAAGCCCTGCCTGGGCC CCGGGCCCGGCGCACCTGCCTTCCCCAGCCCCTACAGTGCAGCAGTGTCGCCCTACTCTT GCTACGGAGGCTACAGCGGAGCACCCTACGGCGCAGGCTACGGCACCTGCTACGCGGGCG CGCCCTCGGGTCCTGCGCCACACACACCACTGGCCAGCGCGGGCTTCGGACACGGTGGCC AGAATGCCACCCCGCAGGGCCATCTGGCAGCCACGCTGCAGGGTGTCAGGGCCTGGTGA OMIM ID 611770