| Entrez gene ID | | 1369 |
|
| Official gene symbol | | CPN1 |
|
| Full name | | carboxypeptidase N, polypeptide 1 |
|
| Aliases | | ,CPN,FLJ40792,SCPN, |
|
| Gene summary | | Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq] |
|
| Location | | Chromosome: 10 Locus: 10q24.2 |
|
| Gene position | | 101841642 - 101802065 Map Viewer |
|
| Gene orientation | | minus |
|
| Gene size | | 39578 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 603103 |
|
|
|
